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间充质干细胞对急性肾损伤Secretomes:可能的异质性

表1

溶性因素从msc。

细胞因子 趋化因子
il - 1α CCL1
il - 1β CCL2
- 2 CCL5
IL-3 CCL8
il - 6 CCL11
IL-7 CCL15
il - 10 CCL16
IL-11 CCL18
il - 12 CCL22
IL-13 CCL23
IL-16 CCL24
干扰素-γ CCL26
肿瘤坏死因子-α 处于受控
生活 CXCL2
TGF -β CXCL3
MIF CXCL5
OSM CXCL6
g - csf CXCL8
csf CXCL11
gm - csf CXCL12
FLT3LG CXCL13
自洽场 CX3CL1
促血小板生成素 XCL1
TSG-6
其他因素
血管生成因子 CXCR3
血管生成素 PGE2
检验 PAI-1
VEGF MMP1
MMP3
生长因子 MMP9
HGF MMP10
表皮生长因子 MMP13
igf - 1 TIMP-1
FGF-2 TIMP-2
FGF-4 TIMP-3
FGF-7 TIMP-4
FGF-9 瘦素
BMP-7 IGFBP-1
BDGF IGFBP-2
GDNF IGFBP-3
神经生长因子 IGFBP-4
PIGF 脂联素
PDGF Adrenomedullin
Osteoprotegerin

IL:白介素;干扰素:干扰素;肿瘤坏死因子:肿瘤坏死因子;生活:白血病抑制因子;TGF:转化生长因子;MIF:巨噬细胞迁移抑制因子;OSM:制瘤素M;g - csf:粒细胞集落刺激因子;csf:巨噬细胞集落刺激因子;gm - csf:粒细胞巨噬细胞集落刺激因子; FLT3LG: Fms-related tyrosine kinase 3 ligand; SCF: stem cell factor; TSG-6: TNF-stimulated gene 6; VEGF: vascular endothelial growth factors; HGF: hepatocyte growth factor; EGF: epidermal growth factor; IGF: insulin-like growth factor; FGF: fibroblast growth factor; BMP: bone morphogenetic protein; BDNF: brain-derived neurotrophic factor; GDNF: glial cell-derived neurotrophic factor; NGF: nerve growth factor; PIGF: placenta growth factor; PDGF: platelet-derived growth factor; CCL: C-C motif chemokine ligand; CXCL: C-X-C motif chemokine ligand; CX3CL: C-X3-C motif chemokine ligand; XCL: X-C motif chemokine ligand; CXCR: C-X-C motif chemokine receptor; PGE2; prostaglandin E2; PAI: plasminogen activator inhibitor; MMP: matric metalloproteinase; TIMP: tissue inhibitor of metalloproteinase; IGFBP: insulin-like growth factor-binding protein.