氧化医学和细胞寿命
研究文章

PGC-1α诱导肺动脉高血压

表2

多元回归分析的临床、分子和生化特性IPAH患者。
PGC-1α 6 MWT 年龄 人民行动党 CI PVR CYTC 草皮 助教 GPX PaO2
PGC-1α 0.15585 0.03470 0.00041 0.04289 0.00625 0.00012 0.00277 0.00206 0.00010 0.00618 值
6 MWT 0.15585 0.00451 0.07089 0.70377 0.55674 0.06251 0.12445 0.01532 0.09516 0.01279
年龄 0.03470 0.00451 0.04786 0.35841 0.31914 0.03581 0.04786 0.03317 0.01683 0.01097
人民行动党 0.00041 0.07089 0.04786 0.00791 0.00824 0.00000 0.00033 0.00136 0.00095 0.00705
CI 0.04289 0.70377 0.35841 0.00791 0.00053 0.01155 0.01412 0.26858 0.10484 0.06642
PVR 0.00625 0.55674 0.31914 0.00824 0.00053 0.00136 0.04461 0.05484 0.01025 0.07415
CYTC 0.00012 0.06251 0.03581 0.00000 0.01155 0.00136 0.00136 0.00015 0.00008 0.00209
草皮 0.00277 0.12445 0.04786 0.00033 0.01412 0.04461 0.00136 0.01391 0.00736 0.00038
助教 0.00206 0.01532 0.03317 0.00136 0.26858 0.05484 0.00015 0.01391 0.00033 0.00401
GPX 0.00010 0.09516 0.01683 0.00095 0.10484 0.01025 0.00008 0.00736 0.00033 0.00554
PaO2 0.00618 0.01279 0.01097 0.00705 0.06642 0.07415 0.00209 0.00038 0.00401 0.00554
PGC-1α 0.43663 −0.61973 −0.87326 0.60071 −0.75354 0.92960 0.78171 0.79579 0.95073 0.73852 相关系数
6 MWT 0.43663 −0.75524 −0.53846 0.12281 −0.18881 0.55245 0.46853 0.67832 0.50350 0.69123
年龄 −0.61973 −0.75524 0.58042 −0.29123 0.31469 −0.60839 −0.58042 −0.61538 −0.67133 −0.70176
人民行动党 −0.87326 −0.53846 0.58042 −0.72281 0.72028 −0.94406 −0.86014 −0.81119 −0.82517 −0.72983
CI 0.60071 0.12281 −0.29123 −0.72281 −0.84562 0.69825 0.68421 0.34737 0.49123 0.54577
PVR −0.75354 −0.18881 0.31469 0.72028 −0.84562 −0.81119 −0.58741 −0.56643 −0.70629 −0.53334
CYTC 0.92960 0.55245 −0.60839 −0.94406 0.69825 −0.81119 0.81119 0.88112 0.89510 0.79299
草皮 0.78171 0.46853 −0.58042 −0.86014 0.68421 −0.58741 0.81119 0.68531 0.72727 0.85615
助教 0.79579 0.67832 −0.61538 −0.81119 0.34737 −0.56643 0.88112 0.68531 0.86014 0.76141
GPX 0.95073 0.50350 −0.67133 −0.82517 0.49123 −0.70629 0.89510 0.72727 0.86014 0.74386
PaO2 0.73852 0.69123 −0.70176 −0.72983 0.54577 −0.53334 0.79299 0.85615 0.76141 0.74386
PaO2:动脉血液中氧的分压、6 MWT: 6分钟步行试验,行动党:肺动脉压力,CI:心脏指数,PVR:肺血管阻力、VR: vasoreactivity PGC-1α:过氧物酶体proliferator-activated受体γ共激活剂1 -α再保险:相对mRNA表达,CYTC:细胞色素c, SOD:超氧化物歧化酶,助教:总抗氧化状态、GPX:谷胱甘肽过氧化物酶。