|
|
内源性配体 |
TLR |
NLR |
其他人 |
引用 |
|
| 蛋白质、多肽 |
淀粉样蛋白- |
TRL2, TLR4/6 |
NLRP3 |
|
(19- - - - - -21] |
| 补膜攻击复杂 |
|
NLRP3 |
|
(22] |
| α和βdefensins |
TLR4 |
NLRP3 |
|
(23,24] |
| Eosinophil-derived神经毒素 |
TLR2 |
|
|
(25] |
| 胎球蛋白一 |
TLR4 |
|
|
(26] |
| 纤维蛋白原 |
TLR4 |
|
|
(27] |
| Fibronectin-EDA |
TLR2 TLR4 |
|
|
(11,28- - - - - -30.] |
| HMGB1 |
TLR2、TLR4和TLR9识别 |
|
愤怒 |
(31日- - - - - -34] |
| HSP60 |
TLR2 TLR4 |
|
|
(35- - - - - -37] |
| HSP70 |
TRL2, TLR4/6 |
|
|
(38] |
| 骨桥蛋白 |
TLR9识别(MyD88) |
|
|
(39] |
| S100A8 / A9 |
TLR4 |
NLRP3 |
愤怒 |
(40- - - - - -42] |
| Tenascin-C |
TLR4 |
|
|
(43] |
| 肿瘤坏死因子- |
NLRP3 |
|
|
(44] |
|
| 蛋白聚糖、葡糖氨基葡聚糖 |
实验 |
TLR2 TLR4 |
NLRP3 |
|
(45,46] |
| 透明质酸的碎片 |
TLR2 TLR4 |
|
|
(47,48] |
| Versican |
TLR2/6 |
|
|
(49] |
|
| 脂肪酸,脂蛋白 |
胆固醇晶体 |
|
NLRP3 |
|
(50] |
| 氧化低密度脂蛋白 |
TLR2、TLR4和TLR4/6 |
|
|
(20.,51] |
| 饱和脂肪酸 |
TLR4 |
|
|
(52] |
| 血清淀粉样蛋白一 |
TLR2 TLR4 |
NLRP3 |
|
(53- - - - - -55] |
|
| 核酸 |
线粒体DNA |
TLR9识别 |
AIM2, NLRP3 |
|
(54,56,57] |
| 信使核糖核酸 |
TLR3 |
|
|
(58] |
| 党卫军RNA |
TLR7, TLR8 |
|
|
(59] |
|
| Protein-nucleotide复合物 |
IgG-chromatin复合物 |
TLR9识别 |
|
|
(60] |
| HMGB1-nucleosome复杂 |
TLR2 |
|
|
(61年] |
|
| 嘌呤代谢产物 |
三磷酸腺苷 |
|
NLRP1b, NLRP3 |
|
(62年,63年] |
| 尿酸 |
TLR2 TLR4 |
NLRP3 |
|
(64年,65年] |
|
|
