研究文章
小变化在盐水中血浆肾素活性测试提供一个辅助为原发性醛固酮增多症的诊断价值
|
| 标准 |
一个 |
B |
C |
D |
E |
|
| Post-SIT PRA < 0.36 (ng / ml / h) |
√ |
|
|
|
|
| ΔPRA≤0.5 (ng / ml / h) |
|
√ |
|
|
√ |
| Post-SIT ARR > 34 (ng / dl) / (ng / ml / h) |
|
|
√ |
|
√ |
| Post-SIT PAC /ΔPRA > 21 (ng / dl) / (ng / ml / h) |
|
|
|
√ |
|
| 预测措施:Est。%(95%置信区间) |
|
|
|
|
|
| 灵敏度 |
85.4% |
90.3% |
89.2% |
90.6% |
81.6% |
| (79.5 - -90.2) |
(85.1 - -94.1) |
(83.8 - -93.3) |
(85.3 - -94.6) |
(75.3 - -86.9) |
| 特异性 |
74.8% |
75.6% |
90.7% |
84.3% |
97.0% |
| (70.2 - -79.1) |
(71.0 - -79.8) |
(87.3 - -93.4) |
(80.3 - -87.8) |
(94.6 - -98.4) |
| PPV |
62% |
64.0% |
82.1% |
72.1% |
92.6% |
| (55.7 - -67.9) |
(57.8 - -69.8) |
(76.1 - -87.1) |
(65.6 - -78.0) |
(88.5 - -94.1) |
| 净现值 |
91.4% |
94.2% |
94.6% |
95.3% |
91.6% |
| (87.8 - -94.3) |
(90.9 - -96.5) |
(91.8 - -96.7) |
(92.4 - -97.3) |
(88.5 - -94.1) |
| + L |
3.90 |
3.70 |
9.54 |
5.79 |
26.19 |
| −L |
0.20 |
0.13 |
0.12 |
0.11 |
0.15 |
| Youden |
0.602 |
0.659 |
0.798 |
0.749 |
0.785 |
| AUC |
0.855 |
0.897 |
0.973 |
0.893 |
0.951 |
| (0.823 - -0.882) |
(0.869 - -0.920) |
(0.960 - -0.982) |
(0.864 - -0.917) |
(0.930 - -0.967) |
|
|
|
Post-SIT加勒比海盗,aldosterone-to-renin比盐水后测试;Post-SIT PRA、血浆肾素活性后,盐水测试;PPV,积极预测价值;NPV, negative-predictive价值;AUC,曲线下的面积;+ L、阳性似然比;−L -似然比。ΔPRA = PRA pre-SIT−PRA post-SIT;PAC post-SIT /ΔPRA = PAC post-SIT / (PRA pre-SIT−PRA post-SIT)。
|
