研究文章
每天一次的功效Darunavir /例如PI-Naive, NNRTI-Experienced病人欧丁神的审判
表4
hiv - 1 RNA抑制在48周,由活跃种转录和基准CD4细胞计数。
|
|
内/例如
800/100毫克每天一次 |
内/例如
600/100毫克每日两次 |
|
|
|
|
| hiv - 1 RNA < 50拷贝/毫升 |
|
|
| 活跃种转录 |
|
|
| 0 |
6/7 (86%) |
8/9 (89%) |
| 1 |
30/34 (88%) |
32/35 (91%) |
| ≥2 |
64/85 (75%) |
69/88 (78%) |
|
| hiv - 1 RNA < 400拷贝/毫升 |
|
|
| 活跃种转录 |
|
|
| 0 |
6/7 (86%) |
9/9 (100%) |
| 1 |
31/34 (91%) |
32/35 (91%) |
| ≥2 |
64/85 (75%) |
74/88 (84%) |
|
| hiv - 1 RNA < 50拷贝/毫升 |
|
|
| 基准CD4细胞计数 |
|
|
| < 200个细胞/µl |
49/59 (83%) |
41/54 (76%) |
| ≥200细胞/µl |
62/76 (82%) |
68/83 (82%) |
|
| hiv - 1 RNA < 400拷贝/毫升 |
|
|
| 基准CD4细胞计数 |
|
|
| < 200个细胞/µl |
51/59 (86%) |
44/54 (82%) |
| ≥200细胞/µl |
67/76 (88%) |
71/83 (86%) |
|
|
