表1
协会的分析MTIF3 rs7669基因型和等位基因频率在帕金森病(PD)。
|
| MTIF3 |
家族性帕金森病(n =90) |
零星的PD (n =291) |
结合样本(n =381) |
控制(n =322) |
|
| 基因型 |
|
|
|
|
| CC (%) |
59 (65.6) |
168 (57.7) |
227 (59.6) |
211 (65.5) |
| CT (%) |
28日(31.1) |
108 (37.1) |
136 (35.7) |
96 (29.8) |
| TT (%) |
3 (3.3) |
15 (5.2) |
18 (4.7) |
15 (4.7) |
|
|
|
|
|
|
| 等位基因 |
|
|
|
|
| C (%) |
146 (81.1) |
444 (76.3) |
590 (77.4) |
518 (80.4) |
| T (%) |
34 (18.9) |
138 (23.7) |
172 (22.6) |
126 (19.6) |
|
|
|
|
|
|
| 优势比 |
1.045 (0.686 - -1.59) |
0.783 (0.596 - -1.03) |
0.834 (0.644 - -1.08) |
|
| 结合基因型 |
|
|
|
|
| CC / CT (%) |
87 (96.7) |
276 (94.8) |
363 (95.3) |
307 (95.3) |
| TT (%) |
3 (3.3) |
15 (5.2) |
18 (4.7) |
15 (4.7) |
|
|
|
|
|
|
| 优势比 |
1.42 (0.401 - -5.01) |
0.899 (0.432 - -1.87) |
0.985 (0.488 - -1.99) |
|
| TT / CT (%) |
31 (34.4) |
123 (42.3) |
154 (40.4) |
111 (34.5) |
| CC (%) |
59 (65.6) |
168 (57.7) |
227 (59.6) |
211 (65.5) |
|
|
|
P= .0473 |
|
|
| 优势比 |
0.999 (0.612 - -1.63) |
1.39 (1.01 - -1.93) |
1.29 (0.948 - -1.75) |
|
|
|
一个卡方检验(χ22)(df)列联表,(1 df)列联表。
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