VCAM-1 ICAM-1 希利 il - 6 引发 促炎表型HG / thrombin-stimulated HAECs被mir - 146减毒——模仿。使用炎症细胞因子(a)分析工具显示,HG /凝血酶引发的刺激效应和il - 6蛋白表达条件媒介是保存在miR-control-transfected HAECs,同时刺激效应在mir - 146 a mimic-transfected减毒,HG / thrombin-stimulated HAECs。显示的图像代表三个独立实验的结果。(b)的刺激效果HG /凝血酶THP-1粘附HAECs是保存在miR-control-transfected HAECs,虽然THP-1粘性在mir - 146 a mimic-transfected减毒,HG / thrombin-stimulated HAECs miR-control-transfected中34%的工厂。酒吧代表意味着从4±SEM实验。,如与miR-control相比。(c)的刺激效果HG /凝血酶的基因表达,,,,显著降低mir - 146 a mimic-transfected, HG / thrombin-stimulated HAECs至42%,51%,71%,40%,和34%的miR-control-transfected, HG / thrombin-stimulated HAECs。酒吧代表±SEM手段从3实验。和,如与miR-control相比。