.0001). The control group showed less edema in fat tissue than the
ischemia-alone group (P<.05). All of the flaps in the
ischemia-only group showed significantly less bleeding and edema
than I-R group (P< .001). The ratio of MDA/GSH was 33 in
control, 37 in ischemia alone, and 82 in ischemia-reperfusion
groups, respectively. This study confirms that significant
histologic and biochemical alteration occurs after ischemia and
ischemia-reperfusion events in adipose tissue. Marked drop in
adipose tissue antioxidant levels after I-R suggested that
preemptive measures to this decrease should be undertaken in
clinical settings.">
脂肪膜组织缺血再灌注损伤：一种评估大鼠早期组织学和生化改变的实验研究据/title>
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</a>那据sup>1据/sup></span>
<span class="">ergul belge kurutas.据!-- -->那据sup>2据/sup>
<!-- -->和据/span>
<span class="">Harun Ciralik.据sup>3.据/sup></span>
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<p><sup>1据/sup><span>萨特科米姆大学医学系，医学系，Kahramanmaras 46050，土耳其据/span></p>
<p><sup>2据/sup><span>生物化学系，医学院，萨特科姆大学，Kahramanmaras 46050，土耳其据/span></p>
<p><sup>3.据/sup><span>医学系，医学系，Sutcuimam University，Kahramanmaras 46050，土耳其据/span></p>
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<span class="articleContent__PublicationField-sc-2yl9jy-6 cIribm">收到据/span>
<span class="articleContent__PublicationValue-sc-2yl9jy-7 khHUcu">2005年5月17日据/span>
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<span class="articleContent__PublicationField-sc-2yl9jy-6 cIribm">接受据/span>
<span class="articleContent__PublicationValue-sc-2yl9jy-7 khHUcu">2005年6月02日据/span>
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<article class="sc-jtRlXQ hkyIvx article_body ">
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<h4 class="header" id="abstract">摘要据/h4>
<p>脂肪坏死仍然是重建襟翼的严重并发症。在临床环境中，众所周知，脂肪组织更容易受到缺血事件的影响。我们的旨在评估脂质模型中脂肪血管组织的早期组织学和生化变化。大鼠中的椎骨瓣模型用于评估缺血再灌注（I-R）损伤对脂肪组织的影响。两组动物（单独缺血和其他缺血再灌注组的动物）用于评估组织学水肿，充血和血管外出血的程度，以及腺毛瓣内的早期生物化学改变。生物化学参数包括谷胱甘肽（GSH）和丙二醛（MDA）。在每组中，对侧腹股肌皮下脂肪组织用作对照。将这些评估与正常的非肿瘤腹部皮下脂肪组织进行比较。缺血再灌注瓣组在组织学上显示出比对照组的显着大量水肿充血和出血（据mml:math alttext="$P<$" id="E1" xmlns:mml="http://www.w3.org/1998/Math/MathML">
<mml:mi>
P.据/mml:mi>
<mml:mo>
据据/mml:mo>
</mml:math>.0001）。对照组在脂肪组织中显示出比缺血组群体更少的水肿（据mml:math alttext="$P < .05$" id="E2" xmlns:mml="http://www.w3.org/1998/Math/MathML">
<mml:mi>
P.据/mml:mi>
<mml:mo>
据据/mml:mo>
<mml:mn>
.05据/mml:mn>
</mml:math>）。只有缺血的组中的所有襟翼显示出明显较少的出血和水肿而不是I-R组（据mml:math alttext="$P<$" id="E3" xmlns:mml="http://www.w3.org/1998/Math/MathML">
<mml:mi>
P.据/mml:mi>
<mml:mo>
据据/mml:mo>
</mml:math>.001）。MDA / GSH的比例为33，单独缺血37例，分别为82个缺血再灌注组。该研究证实，在脂肪组织中缺血和缺血再灌注事件发生后发生显着的组织学和生化改变。I-R后脂肪组织抗氧化水平的标记下降表明在临床环境中应进行对此减少的先发制人措施。据/p>
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<h4 class="copyright" id="copyright">版权所有据/h4>
<p>版权所有©2005 Hindwi Publishing Corporation。这是分布下的开放式访问文章据a rel="license" href="http://creativecommons.org/licenses/by/3.0/">创意公共归因许可证据/a>如果正确引用了原始工作，则允许在任何媒体中的不受限制使用，分发和再现。据/p>
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意见据span>131.据/span>
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下载据span>614.据/span>
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