研究文章
分子拥挤的影响的结构和稳定性G-Quadruplexes步行不能的网站
表2
美联社的热力学参数系列G-quadruplex的形成一个。
|
|
PEG200 (wt %) |
b (°C) |
(千卡摩尔−1) |
(千卡摩尔−1) |
(千卡摩尔−1) |
c (千卡摩尔−1) |
d (千卡摩尔−1) |
|
| AP-0 |
0 |
58.1 |
−47.9±0.3 |
−44.8±0.3 |
−3.1±0.4 |
−2.3±1.0 |
- - - - - - |
| 40 |
66.9 |
−62.1±1.0 |
−56.6±0.8 |
−5.5±1.0 |
- - - - - - |
- - - - - - |
| AP-1 |
0 |
52.2 |
−41.3±0.4 |
−39.4±0.5 |
−1.9±0.6 |
−1.6±1.0 |
1.2±0.7 |
| 40 |
61.9 |
−46.5±0.6 |
−43.0±0.6 |
−3.5±0.8 |
- - - - - - |
1.9±1.2 |
| AP-2 |
0 |
44.2 |
−40.8±0.5 |
−39.9±0.5 |
−0.9±0.3 |
−1.5±1.0 |
2.2±0.5 |
| 40 |
53.2 |
−48.2±0.8 |
−45.8±0.7 |
−2.4±0.8 |
- - - - - - |
3.0±1.3 |
| AP-3 |
0 |
50.0 |
−42.1±0.6 |
−40.4±0.6 |
−1.7±0.7 |
−1.2±1.5 |
1.4±0.8 |
| 40 |
57.2 |
−47.9±1.0 |
−45.0±0.9 |
−2.9±1.4 |
- - - - - - |
2.5±1.7 |
| AP-4 |
0 |
39.1 |
−38.6±0.3 |
−38.3±0.3 |
−0.3±0.3 |
−1.1±0.3 |
2.8±0.5 |
| 40 |
46.2 |
−47.9±0.4 |
−46.3±0.3 |
−1.4±0.3 |
- - - - - - |
4.0±1.0 |
| AP-5 |
0 |
30.9 |
−32.6±0.3 |
−33.3±0.3 |
0.7±0.3 |
−1.7±0.6 |
3.8±0.5 |
| 40 |
43.8 |
−46.1±0.4 |
−45.1±0.4 |
−1.0±0.5 |
- - - - - - |
4.4±1.1 |
| 厄运 |
0 |
47.0 |
−40.7±0.4 |
−39.4±0.4 |
−1.3±0.6 |
−1.5±0.9 |
1.8±0.7 |
| 40 |
56.1 |
−48.1±0.6 |
−45.3±0.6 |
−2.8±0.7 |
- - - - - - |
2.6±1.2 |
| AP-7 |
0 |
43.5 |
−45.1±0.4 |
−44.2±0.4 |
−0.9±0.5 |
−1.3±0.9 |
2.2±0.6 |
| 40 |
51.3 |
−48.4±0.4 |
−46.1±0.4 |
−2.2±0.5 |
- - - - - - |
3.2±1.1 |
| AP-8 |
0 |
33.5 |
−31.3±0.3 |
−31.7±0.3 |
0.4±0.3 |
−1.8±0.6 |
3.5±0.5 |
| 40 |
46.7 |
−46.4±0.3 |
−45.0±0.3 |
−1.4±0.3 |
- - - - - - |
4.0±1.0 |
| AP-9 |
0 |
41.1 |
−35.2±0.2 |
−33.3±0.3 |
−0.5±0.3 |
−1.4±0.4 |
2.6±0.5 |
| 40 |
49.5 |
−47.5±0.4 |
−45.6±0.3 |
−1.9±0.3 |
- - - - - - |
3.5±1.0 |
| AP-10 |
0 |
38.8 |
−37.5±0.4 |
−37.3±0.4 |
−0.2±0.5 |
−1.3±0.6 |
2.9±0.6 |
| 40 |
48.0 |
−44.8±0.3 |
−43.3±0.3 |
−1.5±0.4 |
- - - - - - |
3.9±1.1 |
| AP-11 |
0 |
36.4 |
−33.3±0.7 |
−33.5±0.7 |
0.2±0.7 |
−1.9±1.1 |
3.3±0.9 |
| 40 |
48.1 |
−42.8±0.7 |
−41.1±0.6 |
−1.7±0.7 |
- - - - - - |
3.7±1.2 |
|
|
一个所示的错误值计算(44]。 b
熔化温度在20吗μ米总链浓度。 c
。 d
(显示的数字从1到11)。
|