研究文章
多态性在干扰素γ、il - 10和TGFβ基因可能与hiv - 1感染有关
表2
等位基因和基因型频率分布在干扰素的基因γ,肿瘤坏死因子α、il - 10、il - 6、TGFβ细胞因子在组织研究。
|
| 基因型和等位基因 |
hiv - 1 (%) |
控制(%) |
|
或 |
|
|
= 216 |
= 294 |
(95%置信区间) |
|
| 干扰素γ |
|
|
|
|
|
| AA |
111 (51.39) |
117 (39.79) |
0.0336 |
1.5776 |
0.0198 |
| 在 |
89 (41.20) |
148 (50.35) |
|
(1.09 - -2.28) |
|
| TT |
16 (7.41) |
29 (9.86) |
|
|
|
| 一个 |
311 (71) |
382 (65) |
0.0172 |
1.3860 |
0.0210 |
| T |
121 (29) |
206 (35) |
|
(1.05 - -1.81) |
|
| 肿瘤坏死因子α |
|
|
|
|
|
| AA |
4 (1.86) |
6 (2.04) |
0.9887 |
0.9922 |
0.9416 |
| AG) |
42 (19.44) |
57 (19.39) |
|
(0.25 - -3.26) |
|
| GG |
170 (78.70) |
231 (78.57) |
|
|
|
| 一个 |
50 (12) |
69 (12) |
0.9372 |
0.9845 |
0.9843 |
| G |
382 (88) |
519 (88) |
|
(0.66 - -1.45) |
|
| il - 10 |
|
|
|
|
|
| AA |
123 (56.94) |
159 (54.09) |
0.7645 |
1.3261 |
0.5368 |
| AG) |
79 (36.58) |
111 (37.75) |
|
(0.65 - -2.67) |
|
| GG |
14 (6.48) |
24 (8.16) |
|
|
|
| 一个 |
325 (75) |
429 (73) |
0.4139 |
1.1257 |
0.4565 |
| G |
107 (25) |
159 (27) |
|
(0.84 - -1.49) |
|
| il - 6 |
|
|
|
|
|
| GG |
142 (65.74) |
184 (62.59) |
0.1856 |
2.7011 |
0.1241 |
| GC |
70 (32.41) |
96 (32.65) |
|
(0.87 - -8.38) |
|
| CC |
4 (1.85) |
14 (4.76) |
|
|
|
| G |
354 (82) |
464 (79) |
0.2288 |
1.2129 |
0.2621 |
| C |
78 (18) |
124 (21) |
|
(0.88 - -1.66) |
|
| TGFβ |
|
|
|
|
|
| TT |
43 (19.91) |
59 (20.07) |
0.2136 |
0.7959 |
0.4439 |
| TC |
97 (44.91) |
152 (51.70) |
|
(0.48 - -1.31) |
|
| CC |
76 (35.18) |
83 (28.23) |
|
|
|
| T |
183 (42) |
270 (46) |
0.2587 |
0.8656 |
0.2864 |
| C |
249 (58) |
318 (54) |
|
(0.67 - -1.11) |
|
|
|
:分析两组之间(确切概率法或卡方检验)。:优势比。
|
