研究文章
临床特征和预后的伴随原发性胆汁胆管炎和自身免疫性疾病:一项回顾性研究
表2
患者的临床特征和实验室结果原发性胆汁胆管炎和原发性胆汁胆管炎复杂与干燥综合征。
|
| 参数 |
中国人民银行集团(n= 328) |
PBC-SS集团(n= 133) |
价值 |
|
| ALT (U / L) |
56.60 (28.70 - -111.10) |
54.20 (30.20 - -90.10) |
0.419 |
| AST (U / L) |
70.30 (41.55 - -114.90) |
74.20 (49.30 - -107.80) |
0.714 |
| 治疗组(μ摩尔/升) |
27.80 (14.90 - -75.30) |
27.90 (18.30 - -64.30) |
0.585 |
| DBIL (μ摩尔/升) |
15.00 (5.80 - -53.35) |
13.50 (8.80 - -52.20) |
0.512 |
| TP (g / L) |
70.60 (63.60 - -76.70) |
70.20 (63.90 - -81.50) |
0.313 |
| 铝青铜(g / L) |
34.80 (29.60 - -38.80) |
33.30 (29.70 - -36.80) |
0.008
|
| GGT (U / L) |
168.5 (76.9 - -358.8) |
156.3 (118 - 305.6) |
0.284 |
| 高山(U / L) |
189.30 (114.40 - -340.80)(114.40∼340.80) |
245.8 (162.4 - -454.7) |
0.558 |
| 白细胞计数(109 / L) |
4.63 (3.42 - -6.30) |
3.22 (2.58 - -4.22) |
0.013
|
| NE百分比(%) |
59.06 (50.38 - -68.90) |
58.8 (49.85 - -65.74) |
0.682 |
| Hb (g / L) |
114.6 (98.60 - -128.00) |
112.9 (79.8 - -121.8) |
0.003
|
| PLT (109 / L) |
129.90 (77.30 - -196.20) |
84.40 (76.00 - -124.00) |
0.118 |
| PT (s) |
12.30 (11.10 - -14.10) |
12.60 (11.50 - -13.80) |
0.128 |
| APTT (s) |
34.30 (30.83 - -37.75) |
36.25 (34.00 - -37.68) |
0.321 |
| 尿素(更易/ L) |
4.85 (3.82 - -6.58) |
4.82 (3.76 - -6.23) |
0.102 |
| 克雷亚(更易/ L) |
57.00 (50.00 - -67.95) |
56.00 (47.00 - -75.00) |
0.374 |
| IgM (g / L) |
2.79 (1.58 - -4.25) |
2.62 (1.47 - -5.10) |
0.541 |
| 免疫球蛋白g (g / L) |
15.40 (12.50 - -19.00) |
17.70 (11.33 - -22.65) |
0.111 |
| 法新社(ng / mL) |
3.70 (2.58 - -5.50) |
3.70 (2.00 - -5.40) |
0.139 |
| TC(更易/ L) |
4.29 (3.39 - -5.49) |
4.32 (3.29 - -5.13) |
0.391 |
| TG(更易/ L) |
1.05 (0.66 - -1.58) |
1.02 (0.66 - -1.54) |
0.241 |
| 高密度脂蛋白胆固醇(更易/ L |
1.08 (0.60 - -1.51) |
1.02 (0.46 - -1.27) |
0.015
|
| 低密度(更易/ L) |
2.32 (1.69 - -3.04) |
2.44 (1.74 - -2.83) |
0.177 |
| Ca2 +(更易/ L) |
2.18 (2.06 - -2.27) |
2.15 (2.08 - -2.25) |
0.004
|
| 无机磷(更易/ L) |
1.08 (0.96 - -1.20) |
1.11 (0.95 - -1.19) |
0.116 |
| 安娜+ |
164/280 (58.6%) |
76/125 (60.80%) |
0.673 |
| ACA + |
60/319 (18.81%) |
25/126 (19.84%) |
0.803 |
| SS-A / Ro-52kD + |
95/287 (33.10%) |
57/118 (48.31%) |
0.004
|
| AMA + |
218/312 (69.9%) |
107/130 (82.3%) |
0.007
|
| AMA-M2 + |
191/314 (60.80%) |
101/129 (78.3%) |
< 0.001
|
| 疲劳 |
132/328 (40.24%) |
44/133 (33.08%) |
0.152 |
| 瘙痒 |
44/328 (40.24%) |
12/133 (9.02%) |
0.191 |
| 肝硬化 |
219/328 (66.77%) |
107/133 (80.45%) |
0.003
|
| 儿童得分 |
6.00 (5.00 - -8.00) |
6.00 (6.00 - -8.00) |
0.263 |
| 儿童得分≥7 |
141/328 (42.99%) |
66/133 (49.62%) |
0.194 |
| Fibrosis-4 |
4.79 (2.37 - -8.93) |
5.50 (2.99 - -9.29) |
0.303 |
| 全球得分 |
1.83±1.49 |
1.96±1.52 |
0.507 |
|
|
中国人民银行:原发性胆汁胆管炎;PBC-SS:原发性胆汁胆管炎复杂与干燥综合征;ALT:丙氨酸转氨酶;AST:天冬氨酸转氨酶;治疗组:总胆红素;DBIL:直接胆红素;TP:血清总蛋白;铝青铜:白蛋白;GGT: gamma-glutamyl转移酶;高山:碱性磷酸酶; WBC count: white blood cell count; NE%: neutrophil percentage; Hb: hemoglobin; PLT: platelet count; PT: prothrombin time; APTT: activated partial thromboplastin time; CREA: creatinine; IgM: immunoglobulin M; IgG: immunoglobulin G; AFP: alpha-1-fetoprotein; TC: Total cholesterol; TG: triglycerides; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; Ca 2 +:血清钙;磷酸盐:血清磷;安娜+:抗核抗体阳性;ACA +: anticentromere抗体阳性;SS-A / Ro-52kD: anti-SSA / Ro-52kD抗体阳性;AMA:抗线粒体抗体阳性;AMA-M2 +:抗线粒体antibody-M2线粒体subfraction-positive; 值< 0.05被认为是显著的。
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