研究文章
海藻酸的制备方法在某些特征的影响/壳聚糖/洛伐他汀复合材料
表6
发布常数(k)和回归系数(R
2)获得动能方程反映lv释放D-LSD和ID-LSD样本在pH值7.4解决方案。
|
| 样本 |
佐薇 |
佛 |
HG |
HC |
KP |
| k |
R2 |
k |
R2 |
k |
R2 |
k |
R2 |
k |
n |
R2 |
|
| D-LSD1 |
快的阶段 |
3.10−5 |
0.9281 |
-0.1457 |
0.8359 |
0.0001 |
0.9774 |
-1.10−5 |
0.9281 |
0.6521 |
0.2276 |
0.9825 |
| 缓慢的阶段 |
6.10−7 |
0.9286 |
-0.0016 |
0.9315 |
5.10−6 |
0.8963 |
-2.10−7 |
0.9286 |
0.0307 |
0.8620 |
0.8654 |
|
| D-LSD2 |
快的阶段 |
4.10−5 |
0.8506 |
-0.0898 |
0.7988 |
0.0002 |
0.9275 |
-1.10−5 |
0.8506 |
0.4051 |
0.3820 |
0.9537 |
| 缓慢的阶段 |
9.10−7 |
0.9938 |
-0.0013 |
0.9939 |
8.10−6 |
0.9888 |
-3.10−7 |
0.9938 |
0.0256 |
0.8668 |
0.9785 |
|
| D-LSD3 |
快的阶段 |
7.10−5 |
0.9278 |
-0.1336 |
0.8698 |
0.0003 |
0.9659 |
-2.10−5 |
0.9278 |
0.5851 |
0.2287 |
0.9821 |
| 缓慢的阶段 |
2.10−6 |
0.9740 |
-0.0026 |
0.9729 |
2.10−5 |
0.9855 |
-8.10−7 |
0.9740 |
0.0517 |
0.7411 |
0.9215 |
|
| ID-LSD1 |
快的阶段 |
0.0001 |
0.8039 |
-0.2226 |
0.8487 |
0.0004 |
0.8783 |
-3.10−5 |
0.8039 |
0.8007 |
0.0652 |
0.9876 |
| 缓慢的阶段 |
2.10−6 |
0.9821 |
-0.0044 |
0.5808 |
2.10−5 |
0.982 |
-7.10−7 |
0.9821 |
0.1477 |
0.2593 |
0.8233 |
|
| ID-LSD2 |
快的阶段 |
0.0001 |
0.9446 |
-0.1847 |
0.9016 |
0.0004 |
0.987 |
-4.10−5 |
0.9446 |
0.7243 |
0.1013 |
0.9963 |
| 缓慢的阶段 |
1.10−6 |
0.9551 |
-0.0053 |
0.6684 |
10−5 |
0.9576 |
-4.10−7 |
0.9551 |
0.1549 |
0.4023 |
0.8447 |
|
| ID-LSD3 |
快的阶段 |
7.10−5 |
0.9865 |
-0.1751 |
0.8396 |
0.0003 |
0.9894 |
-2.10−5 |
0.9700 |
0.7865 |
0.1743 |
0.9916 |
| 缓慢的阶段 |
2.10−6 |
0.9618 |
0.0014 |
0.8254 |
2.10−5 |
0.9548 |
-6.10−7 |
0.9618 |
0.0497 |
0.8201 |
0.9460 |
|
| ID-LSD4 |
快的阶段 |
0.0002 |
0.9283 |
-0.1805 |
0.8938 |
0.0007 |
0.9830 |
-5.10−5 |
0.9283 |
0.7779 |
0.0713 |
0.9994 |
| 缓慢的阶段 |
4.10−6 |
0.9929 |
-0.0033 |
0.7872 |
4.10−5 |
0.9843 |
-1.10−6 |
0.9929 |
0.1160 |
0.3259 |
0.9135 |
|
|
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佐薇:零级动力学;佛:一阶动力学;HG: Higuchi模型;HC: Hixson-Croswell模型;KP: Korsmeyer-Peppas模型。
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