|
|
单剂研究 |
|
|
|
价值 |
|
FCM
|
SMC
|
|
|
|
|
|
|
| ≥1事件 |
132 (36.0) |
128 (34.6) |
|
| 恶心想吐 |
15 (4.1) |
18 (4.9) |
0.722 |
| 头疼 |
11 (3.0) |
5 (1.4) |
0.138 |
| 腹泻 |
10 (2.7) |
8 (2.2) |
0.642 |
| 乏力 |
10 (2.7) |
7 (1.9) |
0.474 |
| 便秘 |
7 (1.9) |
13 (3.5) |
0.257 |
| 呕吐 |
4 (1.1) |
14 (3.8) |
0.029 * |
| 腹部疼痛 |
2 (< 1) |
8 (2.2) |
0.107 |
| 尿路感染 |
1 (< 1) |
8 (2.2) |
0.038 * |
|
|
使用研究 |
|
|
|
|
|
FCM |
SMC |
|
|
|
|
|
|
| ≥1事件 |
185 (54.4) |
198 (55.0) |
|
| 降低血磷 |
25 (7.3) |
0 |
< 0.001 * * |
| 头疼 |
16 (4.7) |
18 (5.0) |
0.862 |
| 恶心想吐 |
14 (4.1) |
27日(7.5) |
0.055 |
| 便秘 |
12 (3.5) |
26日(7.2) |
0.031 * |
| 腹泻 |
10 (2.9) |
14 (3.9) |
0.537 |
| 头晕 |
10 (2.9) |
17 (4.7) |
0.242 |
| 上呼吸道感染 |
9 (2.6) |
6 (1.7) |
0.440 |
| 关节痛 |
8 (2.3) |
8 (2.2) |
1.000 |
| 肌痛 |
8 (2.3) |
2 (0.06) |
0.058 |
| 肢体疼痛 |
9 (2.6) |
4 (1.1) |
0.167 |
| 乏力 |
9 (2.6) |
5 (1.4) |
0.287 |
| 增加丙氨酸aminotrasferase |
7 (2.0) |
5 (1/4) |
0.570 |
| 背部疼痛 |
7 (2.0) |
6 (1.7) |
0.784 |
| 鼻咽炎 |
7 (2.0) |
6 (1.7) |
0.784 |
| 尿路感染 |
7 (2.0) |
6 (1.7) |
0.784 |
| 呕吐 |
6 (1.7) |
13 (3.6) |
0.164 |
| 外周水肿 |
3 (< 1) |
8 (2.2) |
0.224 |
| 咳嗽 |
2 (< 1) |
8 (2.2) |
0.108 |
|
|
