研究文章
预后和治疗意义的循环肿瘤细胞表型检测基于年初Epithelial-Mesenchymal过渡标记和Midstage结直肠癌的一线化疗
|
| 变量 |
PFS |
| 意思是(个月) |
95%置信区间 |
卡方 |
Log-rank价值 |
| 下界 |
上界 |
|
| 年龄 |
|
|
|
0.038 |
0.845 |
| ≤55 |
18.21 |
13.725 |
22.685 |
| > 55 |
17.75 |
10.770 |
24.730 |
| 性别 |
|
|
|
0.022 |
0.881 |
| 男性 |
18.51 |
13.342 |
23.683 |
| 女 |
15.06 |
12.016 |
18.095 |
| 淋巴结转移 |
|
|
|
3.218 |
0.073 |
| N0 |
| N1 |
| 程度的肿瘤 |
|
|
|
3.126 |
0.077 |
| 低 |
14.58 |
9.357 |
19.803 |
| 中/高 |
21.88 |
17.979 |
25.771 |
| 肿瘤大小(cm) |
|
|
|
1.126 |
0.289 |
| ≤4 |
14.58 |
11.447 |
22.286 |
| > 4 |
21.88 |
15.988 |
24.699 |
| Total-CTCs -1/5毫升 |
|
|
|
0.177 |
0.674 |
| ≤3 |
18.735 |
14.011 |
23.459 |
| > 3 |
17.500 |
11.682 |
23.318 |
| E-CTCs-1/5毫升 |
|
|
|
0.614 |
0.433 |
| 0 |
17.18 |
12.588 |
21.762 |
| ≥1 |
21.17 |
16.097 |
26.236 |
| E / M-CTCs-1/5毫升 |
|
|
|
1.154 |
0.283 |
| < 2 |
10.45 |
8.088 |
12.818 |
| ≥2 |
19.67 |
15.488 |
23.858 |
| M-CTCs-1/5毫升 |
|
|
|
0.987 |
0.320 |
| 0 |
16.66 |
11.923 |
21.399 |
| ≥1 |
21.17 |
16.097 |
26.236 |
| Total-CTCs -2/5毫升 |
|
|
|
7.354 |
0.007 |
| ≤3 |
22.60 |
19.997 |
25.203 |
| > 3 |
11.07 |
6.835 |
15.311 |
| E-CTCs-2/5毫升 |
|
|
|
4.591 |
0.032 |
| 0 |
20.41 |
16.802 |
24.017 |
| ≥1 |
11.25 |
4.232 |
18.268 |
| E / M-CTCs-2/5毫升 |
|
|
|
2.181 |
0.140 |
| < 2 |
21.78 |
17.671 |
25.884 |
| ≥2 |
15.42 |
10.216 |
20.628 |
| M-CTCs-2/5毫升 |
|
|
|
2.718 |
0.099 |
| 0 |
20.73 |
16.678 |
24.772 |
| ≥1 |
12.75 |
8.317 |
17.183 |
| 总ctc的动态 |
|
|
|
8.116 |
0.004 |
| 减少或不变的 |
| 增加 |
| 动态的E-CTCs |
|
|
|
1.659 |
0.198 |
| 减少或不变的 |
19.41 |
15.573 |
23.254 |
| 增加 |
12.67 |
2.859 |
22.474 |
| E / M-CTCs的动力 |
|
|
|
0.549 |
0.459 |
| 减少或不变的 |
19.11 |
14.484 |
23.743 |
| 增加 |
12.95 |
8.821 |
17.084 |
| 动态的M-CTCs |
|
|
|
5.937 |
0.015 |
| 减少或不变的 |
21.30 |
17.887 |
24.713 |
| 增加 |
11.33 |
6.035 |
16.632 |
|
|
|
|
