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no-repeat 6px;background-position:center;margin-top:10px;min-width:55px;display:none;} @media (min-width:768px){.gvEcCq .floats-partial-section .floats-partial-footer .floats-partial-caption .expand_btn{display:none;}} .gvEcCq .floats-partial-section .floats-partial-footer .floats-partial-caption .caption-text{-webkit-flex:9;-ms-flex:9;flex:9;text-align:left;padding:21px 37px 10px 0px;font-size:16px;font-weight:700;} @media (min-width:768px){.gvEcCq .floats-partial-section .floats-partial-footer .floats-partial-caption .caption-text{padding:19px 18px 10px 18px;}} @media (min-width:992px){.gvEcCq .floats-partial-section .floats-partial-footer .floats-partial-caption .caption-text{padding:19px 21px 10px 21px;}} .gvEcCq .floats-partial-section .floats-partial-footer .floats-partial-caption 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no-repeat 6px;background-position:center;padding:16px 0 16px 0;min-width:62px;max-width:62px;} @media (min-width:768px){.gvEcCq .floats-partial-section .floats-partial-footer .floats-partial-caption .caption-partial-url{padding:16px 0 17px 0;min-width:52px;max-width:52px;}} @media (min-width:992px){.gvEcCq .floats-partial-section .floats-partial-footer .floats-partial-caption .caption-partial-url{padding:15px 0 17px 0;min-width:60px;max-width:60px;}} .gvEcCq .floats-partial-section .floats-partial-footer .floats-partial-caption .caption-partial-url:hover{-webkit-text-decoration:none;text-decoration:none;} .gvEcCq .floats-partial-section .floats-partial-footer .floats-partial-caption-text{font-size:14px;padding:0px 18px 17px 22px;} @media (min-width:768px){.gvEcCq .floats-partial-section .floats-partial-footer .floats-partial-caption-text{padding:0px 15px 15px 18px;}} @media (min-width:992px){.gvEcCq .floats-partial-section .floats-partial-footer .floats-partial-caption-text{padding:0px 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class="threeColumn__ContentWrapper-sc-1bf4078-3 bbzREB contentWrapper"> <div class="threeColumn__Content-sc-1bf4078-4 jknsZc content"> <div class="articleContent__ArticleContentsWrapper-sc-2yl9jy-0 eSvjPB article_contents"> <div class="articleContent__ArticleContentsSectionsWrapper-sc-2yl9jy-1 jntdRu article_contents__sections_wrapper"> <div class="articleContent__ArticleWrapper-sc-2yl9jy-2 hAzjHP"> <div class="sc-chbbiW mBGSe article_header_class"> <p class="sc-kZmsYB bkiEfx article_type">研究文章|开放获取</p> <div class="sc-RcBXQ ztvYg article_citation"> 体积 2011年 <span class="sc-fZwumE cUsFHx">|</span>文章的ID 325470年 <span class="sc-fZwumE cUsFHx">|</span> <a class="sc-htpNat bUhGXt link sc-fQejPQ duuwge" href="https://doi.org/10.1155/2011/325470" aria-label="Doi-link">https://doi.org/10.1155/2011/325470</一个></d我v><d我vclass="sc-LKuAh lcOiDF article_full_citation"> <div class="sc-hzNEM gsmOCv isHide"> <p>j . Alavez-Ramirez j·l·Fuentes-Allen j . Lopez-Estrada, ”<span class="adjust-article-svg-size">无创监测丙型肝炎病毒感染的肝损害</span>”,<i>计算和数学方法在医学</我>, 卷。2011年, 文章的ID325470年, 13   页面, 2011年。 https://doi.org/10.1155/2011/325470</p> </div> <button class="sc-hSdWYo etauus sc-iBEsjs kPshFw" color="">显示引用</button> </div> <h1 class="sc-iRbamj jZOxOO sc-iSDuPN kEVvRd article_title adjust-article-svg-size heading-title">无创监测丙型肝炎病毒感染的肝损害</h1> </div> <div class="sc-jrIrqw eHMFfo article_authors"> <hr class="sc-cEvuZC XkrFe hr__author"> <span class=""><b>j . Alavez-Ramirez</b><a class="sc-htpNat bUhGXt link" href="mailto:" aria-label="Mail Option"><span class="sc-htoDjs kNoiZu sc-hjRWVT irNWJI icon-colored _2zt-1j0LmaF8UjTQAM413G icon-themeable" title="" font-size="16"></span></a>,<sup>1</sup></span> <span class="">j·l·Fuentes-Allen,<sup>2</sup> 和</span> <span class="">j . Lopez-Estrada<sup>3</sup></span> <div class="sc-fHxwqH dMuGGA isHide"> <p><sup>1</sup><span>部门Academica de Ciencias Basicas,大学自治华雷斯德塔巴斯科Cunduacan, 86690年墨西哥、选项卡中,墨西哥</span></p> <p><sup>2</sup><span>la Raza医院de Infectologia Centro医生(Instituto Mexicano del全民社会01200墨西哥,DF、墨西哥</span></p> <p><sup>3</sup><span>Departamento de Matematicas Facultad de Ciencias大学根据墨西哥,04510年墨西哥,DF、墨西哥</span></p> </div> <button class="sc-hSdWYo etauus sc-iQtOjA kfDwZY" color="">显示更多</button> </div> <div class="articleContent__EditorWrapper-sc-2yl9jy-3 evMkvU"> <div class="articleContent__TextWrapper-sc-2yl9jy-8 fYrLtk"> <b>学术编辑器:</b>布莱恩·d·Sleeman</d我v><d我vclass="articleContent__PublicationTimeLineWrapper-sc-2yl9jy-4 fjviok"> <div class="articleContent__PublcationCol-sc-2yl9jy-5 hgKieC notPublished"> <span class="articleContent__PublicationField-sc-2yl9jy-6 cIribm">收到了</span> <span class="articleContent__PublicationValue-sc-2yl9jy-7 khHUcu">2009年11月27日</span> </div> <div class="articleContent__PublcationCol-sc-2yl9jy-5 hgKieC notPublished"> <span class="articleContent__PublicationField-sc-2yl9jy-6 cIribm">接受</span> <span class="articleContent__PublicationValue-sc-2yl9jy-7 khHUcu">2010年12月16日</span> </div> <div class="articleContent__PublcationCol-sc-2yl9jy-5 hgKieC isPublished"> <span class="articleContent__PublicationField-sc-2yl9jy-6 cIribm">发表</span> <span class="articleContent__PublicationValue-sc-2yl9jy-7 khHUcu">2011年2月06</span> </div> </div> </div> <article class="sc-jtRlXQ gvEcCq article_body "> <div> <div class="xml-content"> <h4 class="header" id="abstract">文摘</h4> <p>丙型肝炎的动态的数学模型提出了阿根廷et al .(2002),有四个种群(健康的和不健康的肝细胞,丙型肝炎病毒的病毒载量,和T杀伤细胞),修订。表明减少模型只考虑前三获得的这些数量,称为基本模型中,有两个可能的平衡状态:未感染的病毒是不存在的个体,和流行的病毒和感染细胞。一个阈值参数(基本生殖病毒数量),并在这方面,两两种可能的平衡态的全局稳定性。其他中央在于显示结果,通过模型数值模拟,丙肝病毒造成的肝损伤监测的可行性,避免不必要的活检和不良相关不便/揣摩患者;另一个结果给出了一个数学模型的基础上,最近开发的技术疾病评估本质上基于病毒载量测量。</p> <span class="end-abs"></span> <h4 id="introduction">1。介绍</h4> <p>丙型肝炎病毒(HCV)感染是一个严重的公共卫生问题,并有很强的临床和经济影响。致命的后果可能出现从亚临床急性感染后潜伏期,并最终肝硬化(从20%到30%的情况下)或肝细胞癌(比例小得多)<一个href="#B6">1</一个>),最终事件慢性肝病的最后阶段。并不是在1989年之前,传染性病毒代理被确认为丙肝病毒肝炎患者不是一个而不是B (<一个href="#B21">2</一个>]。目前,六个不同基因型的丙肝病毒已确定不同的生物和临床行为。例如,它已经被观察到的基因型1反应治疗效果低于一个基因型2和3 (<一个href="#B10">3</一个>]。</p> <p>丙肝病毒传播最常见的方式是输血、使用静脉注射药物,血液透析,纹身,高危性行为,医疗和辅助医疗人员的职业博览会,母婴垂直传播给她的产品,并从受感染的器官移植捐赠者。重要的是说,丙肝病毒传播机制是身份不明的很大一部分患者(从20%到40%)<一个href="#B12">4</一个>]。</p> <p>丙肝病毒的潜伏期平均为50天,从15到150天(<一个href="#B21">2</一个>]。影响因素从慢性肝炎向肝硬化进展的速度出现在曝光时间包括年龄,感染持续时间,前度肝损伤,免疫系统状态和丙肝病毒基因型。疾病进展阴险;进化的临床上大量的时间不同:诊断为慢性肝炎,肝硬化,和肝细胞癌约为10,20年,30年,分别为(<一个href="#B6">1</一个>,<一个href="#B26">5</一个>]。大多数病人显示增加的转氨酶水平以及肝细胞损害。食管静脉曲张出血,ascitis、凝血障碍和脑病,等等,可以观察到高级阶段的进化。疾病的进展是变量,而不是总是有序和顺序。病人可以直接从慢性肝炎肝细胞癌不先发展肝硬化,特别是那些与基因型1 b (<一个href="#B26">5</一个>]。</p> <p>丙肝病毒的复制和持久性机制在细胞水平上尚未完全特征。然而,众所周知,它发生在肝,和在肝外没有复制网站报道最新的。由于丙肝病毒的高突变率,大量的不同的免疫变异出现;这种差异在一定程度上解释了病毒能够逃避宿主的免疫控制,感染并最终成为慢性疾病在大多数情况下。此外,强大的病毒的突变使其很难发展一种有效的疫苗。</p> <p>如今,慢性丙型肝炎治疗批准,美国食品和药物管理局(FDA)和欧洲药品局(EMEA),包括管理<svg height="10.85" id="M1" style="vertical-align:-0.1254pt;width:42.25px;" version="1.1" viewbox="0 0 42.25 10.85" width="42.25" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.85)"> <g transform="translate(72,-63.32)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="9.8273582" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="21.16758" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="27.419079" y="0"> ? ?</tspan> </text> </g> </g> </svg>或<svg height="10.8625" id="M2" style="vertical-align:-0.13794pt;width:41.75px;" version="1.1" viewbox="0 0 41.75 10.8625" width="41.75" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.8625)"> <g transform="translate(72,-63.31)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="9.8273582" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="21.16758" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="27.419079" y="0"> ? ?</tspan> </text> </g> </g> </svg>聚乙二醇干扰素联合利巴韦林(<一个href="#B13">6</一个>,<一个href="#B24">7</一个>]。重要的是观察,治疗的中心目标是大幅降低病毒载量(<一个href="#B11">8</一个>- - - - - -- - - - - -- - - - - -- - - - - -- - - - - -- - - - - -<一个href="#B29">10</一个>]。</p> <p>hcv感染患者的治疗基本上取决于他/她的肝损伤的程度。经皮肝活检是一种侵入性的工具,已被广泛用于评估肝损伤的程度,尽管严重的不便。这造成了显著影响医学相关问题提出一个非侵入性程序监测肝损害。</p> <p>在下一节中我们将讨论使用,重要性,不便的经皮肝脏活检。节<一个href="#sec3">3</一个>我们提出一个模型的四个种群(健康的和不健康的肝细胞、病毒载量、和<svg height="10.325" id="M3" style="vertical-align:-0.0pt;width:11.225px;" version="1.1" viewbox="0 0 11.225 10.325" width="11.225" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.325)"> <g transform="translate(72,-63.74)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>致命的细胞),最初提出的阿根廷et al。<一个href="#B4">11</一个>]。节<一个href="#sec4">4</一个>之后,阿根廷,我们发展减少模型的定性分析前三个数量以上。节<一个href="#sec5">5</一个>,我们表明,健康的和不健康的肝细胞群体的进化和病毒载量为模型3和4的数量,几乎是相同的。节<一个href="#sec6">6</一个>,我们提出本研究的主要结果。我们表明,数值减少模型中的参数估计丙型肝炎疾病动态,只使用足够数量的病毒载量测量和种群初始值的合理建议,给我们提供了一种非侵入性技术的基础驴肝损伤。最后,在节<一个href="#sec7">7</一个>我们讨论的结果和他们的影响。</p> <h4 id="liver-biopsies-and-motivation-for-an-alternative">2。肝活检和动机的选择</h4> <p>病人的临床研究开始时他/她的感染状况通过血清学检测丙肝病毒抗体测试。在丙肝病毒阳性患者,病毒载量应该量化为了建立病毒复制的强度。丙肝病毒基因型的鉴定是由分子程序的可检测病毒载量患者;这是必要定义时间的治疗和预后的目的。最后,肝活检,通常由一个经皮穿刺,测量肝组织损伤的程度和范围。</p> <p>经皮肝穿刺活检是一种侵入性的方法,已经被广泛地用于评估的程度(坏死炎性组织活性强度),和舞台(纤维化或肝硬化的存在的程度)的肝损伤。这个方法由提取的一小块肝组织由一根针插入肝脏,它提供了有用的信息对病人进行分类根据疾病的阶段。肝活检被认为是最好的工具来诊断和评估治疗效果<一个href="#B19">12</一个>];然而,它可能是危险的,甚至产生疼痛和时间残疾病人(<一个href="#B16">13</一个>]。另一方面,由于这种方法获得的组织样本很小,它是有争议的,如果他们是代表整个肝脏的状态(<一个href="#B5">14</一个>- - - - - -- - - - - -- - - - - -- - - - - -- - - - - -- - - - - -<一个href="#B25">16</一个>]。</p> <p>由于其不一致性和不便(一些严重),肝脏活组织检查的有效性目前被认为是比以前更重要;它的一些问题点如下。(我)<我>组织的代表性:</我>经皮肝活检获得的组织样本是否真的代表整个肝脏吗?(2)<我>找到reproductiveness。</我>调查结果从不同的样本可以改变不同的病理学家或非常轻微或重大程度,和这种差异似乎是规则,而不是例外。(3)<我>活检的用途:</我>最重要的一点是,活检被认为是有用的分类患者根据疾病的阶段,并确定病人已经开发了肝硬化。在这两个提案,活检似乎并没有真正有用的。(iv)<我>活检徒劳:</我>鉴于患者感染了满意的治疗反应基因型2或3,活检被认为是不必要的。关于基因型1或4,只在50%的情况下,响应执行活检仍在辩论(<一个href="#B10">3</一个>]。</p> <p>恐惧、痛苦和暂时性残疾的病人,是严重的和消极的方面。尽管如此,肝活检仍然是强制性评估阶段和程度的肝脏疾病。另外,现在我们处理的一种新方法来评估肝脏组织的地位,尤其是纤维化阶段,叫弹性成像(Fibroscan),最近才被引入临床实践和尚未在低收入国家/地区。</p> <p>除了血液标记的面板,在另一个非侵入性的工具进展评估肝纤维化的程度(<一个href="#B23">17</一个>]。这些标记可用于建立纤维化的两极(最小的肝纤维化、肝硬化),但更有助于中期评估其范围。特别是,弹性成像是提高结合标记(详情,请参阅[<一个href="#B10">3</一个>])。</p> <p>在过去的年里,病毒载量数被用来作为非侵入性技术,提供了有用的信息在病毒复制的强度,使不必要的肝活检的性能取决于它的病毒基因型(<一个href="#B10">3</一个>]。这种技术也很可靠,已被用于比较前后的感染程度决定一个特定的治疗。</p> <h4 id="dynamics-of-the-hepatitis-c:-model-i">3所示。丙型肝炎:模型的动力学</h4> <p>在本节中,出于完整性的考虑,我们提出简要概括原始模型的动力学丙型肝炎提出(<一个href="#B4">11</一个>),特别注意那些方面与我们的研究目标之间的关系。模型由以下给出系统的常微分方程(ODE):<span class="equation" id="EEq3.1"> <svg height="124.9375" id="M4" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 124.9375" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,124.9375)"> <g transform="translate(72,27.95)"> <text transform="matrix(1,0,0,-1,154.96,64.17)"> <tspan style="font-size: 12.50px; " x="0" y="0"></tspan> <tspan style="font-size: 12.50px; " x="-10.51" y="2.53"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,155.37,58.51)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,163.19,61.64)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,182.21,58.51)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,189.33,61.64)"> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="18.116846" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,218.37,58.51)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,222.72,61.64)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; 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" x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,274.33,35.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,277.55,38.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="-102.91" y="20.49"></tspan> <tspan style="font-size: 12.50px; " x="-110.79" y="23.030001"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="-97.324272" y="23.030001"> =</tspan> <tspan style="font-size: 12.50px; " x="-85.283882" y="23.030001"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="-79.169914" y="23.030001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,209.3,12.44)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,215.3,15.57)"> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,234.26,12.44)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,241.76,15.57)"> <tspan style="font-size: 12.50px; " x="-101.68" y="28.68"></tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="7.1892252" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="-109" y="31.219999"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="-96.647034" y="31.219999"> =</tspan> <tspan style="font-size: 12.50px; " x="-84.619148" y="31.219999"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,164.13,-18.78)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,172.92,-22.98)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="38.459999" y="-14.58"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="9.3800001" y="-7.3299999"> 1</tspan> <tspan style="font-size: 12.50px; " x="18.407166" y="-7.3299999"> - - - - - -</tspan> </text> <g> <path d="m 203.87,-12.53 23.91,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,203.87,-24.4)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,210.75,-27.53)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 米</tspan> <tspan style="font-size: 8.75px; " x="6.8090558" y="0"> 一个</tspan> <tspan style="font-size: 8.75px; " x="10.694944" y="0"> x</tspan> </text> <text transform="matrix(1,0,0,-1,228.97,-22.98)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="11.46" y="-7.3299999"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="21.424891" y="-7.3299999"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="32.765114" y="-7.3299999"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,269.36,-18.78)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,276.07,-15.65)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="6.8766499" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="198.05" y="-34.549999"> (</tspan> <tspan style="font-size: 12.50px; " x="202.2135" y="-34.549999"> 1</tspan> <tspan style="font-size: 12.50px; " x="208.465" y="-34.549999"> )</tspan> </text> </g> </g> </svg></span>在哪里<svg height="14.7125" id="M5" style="vertical-align:-3.2316pt;width:34.5px;" version="1.1" viewbox="0 0 34.5 14.7125" width="34.5" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.7125)"> <g transform="translate(72,-60.23)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-56.69,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="4.1634989" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="8.0769377" y="0"> )</tspan> </text> </g> </g> </svg>健康的肝脏细胞群在时间吗<svg height="9.125" id="M6" style="vertical-align:-0.11285pt;width:5.0124998px;" version="1.1" viewbox="0 0 5.0124998 9.125" width="5.0124998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,9.125)"> <g transform="translate(72,-64.7)"> <text transform="matrix(1,0,0,-1,-71.95,64.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,假设这些细胞复制速度常数<svg height="14.5875" id="M7" style="vertical-align:-3.2316pt;width:14.2875px;" version="1.1" viewbox="0 0 14.2875 14.5875" width="14.2875" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.5875)"> <g transform="translate(72,-60.33)"> <text transform="matrix(1,0,0,-1,-71.95,63.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.97,60.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>人均率和死亡<svg height="10.8375" id="M8" style="vertical-align:-3.2316pt;width:15.075px;" version="1.1" viewbox="0 0 15.075 10.8375" width="15.075" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.8375)"> <g transform="translate(72,-63.33)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,而<svg height="14.7125" id="M9" style="vertical-align:-3.2316pt;width:33.099998px;" version="1.1" viewbox="0 0 33.099998 14.7125" width="33.099998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.7125)"> <g transform="translate(72,-60.23)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-57.81,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="4.1634989" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="8.0769377" y="0"> )</tspan> </text> </g> </g> </svg>受感染的肝细胞群在时间吗<svg height="9.125" id="M10" style="vertical-align:-0.11285pt;width:5.0124998px;" version="1.1" viewbox="0 0 5.0124998 9.125" width="5.0124998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,9.125)"> <g transform="translate(72,-64.7)"> <text transform="matrix(1,0,0,-1,-71.95,64.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>。健康的肝细胞被感染速度的乘积成正比<svg height="14.3625" id="M11" style="vertical-align:-3.2316pt;width:19.200001px;" version="1.1" viewbox="0 0 19.200001 14.3625" width="19.200001" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3625)"> <g transform="translate(72,-60.51)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>和<svg height="10.575" id="M12" style="vertical-align:-0.20064pt;width:12.625px;" version="1.1" viewbox="0 0 12.625 10.575" width="12.625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.575)"> <g transform="translate(72,-63.54)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,比例常数<svg height="10.7375" id="M13" style="vertical-align:-0.13794pt;width:8.6000004px;" version="1.1" viewbox="0 0 8.6000004 10.7375" width="8.6000004" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.7375)"> <g transform="translate(72,-63.41)"> <text transform="matrix(1,0,0,-1,-71.95,63.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,死亡和感染的人均率<svg height="10.8375" id="M14" style="vertical-align:-3.2316pt;width:13.6625px;" version="1.1" viewbox="0 0 13.6625 10.8375" width="13.6625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.8375)"> <g transform="translate(72,-63.33)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>。<svg height="13.45" id="M15" style="vertical-align:-2.21957pt;width:24.4125px;" version="1.1" viewbox="0 0 24.4125 13.45" width="24.4125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,13.45)"> <g transform="translate(72,-61.24)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="7.1892252" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="11.352724" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="15.266163" y="0"> )</tspan> </text> </g> </g> </svg>HCV病毒载量在时间吗<svg height="9.125" id="M16" style="vertical-align:-0.11285pt;width:5.0124998px;" version="1.1" viewbox="0 0 5.0124998 9.125" width="5.0124998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,9.125)"> <g transform="translate(72,-64.7)"> <text transform="matrix(1,0,0,-1,-71.95,64.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>。丙型肝炎病毒感染细胞产生的速度<svg height="9.875" id="M17" style="vertical-align:-2.29482pt;width:7.7624998px;" version="1.1" viewbox="0 0 7.7624998 9.875" width="7.7624998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,9.875)"> <g transform="translate(72,-64.1)"> <text transform="matrix(1,0,0,-1,-71.95,66.44)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>每天每感染细胞病毒粒子。另一方面,病毒与人均恒速死<svg height="10.9" id="M18" style="vertical-align:-3.27548pt;width:19.012501px;" version="1.1" viewbox="0 0 19.012501 10.9" width="19.012501" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.9)"> <g transform="translate(72,-63.28)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>。<svg height="13.45" id="M19" style="vertical-align:-2.21957pt;width:24.025px;" version="1.1" viewbox="0 0 24.025 13.45" width="24.025" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,13.45)"> <g transform="translate(72,-61.24)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="6.8766499" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="11.040149" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="14.953588" y="0"> )</tspan> </text> </g> </g> </svg>的人口吗<svg height="10.325" id="M20" style="vertical-align:-0.0pt;width:11.225px;" version="1.1" viewbox="0 0 11.225 10.325" width="11.225" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.325)"> <g transform="translate(72,-63.74)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>杀伤细胞(CD8<sup>+</sup>细胞毒性细胞)<svg height="9.125" id="M21" style="vertical-align:-0.11285pt;width:5.0124998px;" version="1.1" viewbox="0 0 5.0124998 9.125" width="5.0124998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,9.125)"> <g transform="translate(72,-64.7)"> <text transform="matrix(1,0,0,-1,-71.95,64.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>。这些细胞杀死被感染的速度的乘积成正比<svg height="14.3625" id="M22" style="vertical-align:-3.2316pt;width:17.7875px;" version="1.1" viewbox="0 0 17.7875 14.3625" width="17.7875" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3625)"> <g transform="translate(72,-60.51)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>和<svg height="10.325" id="M23" style="vertical-align:-0.0pt;width:11.225px;" version="1.1" viewbox="0 0 11.225 10.325" width="11.225" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.325)"> <g transform="translate(72,-63.74)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,比例常数<svg height="10.7375" id="M24" style="vertical-align:-0.13794pt;width:7.9875002px;" version="1.1" viewbox="0 0 7.9875002 10.7375" width="7.9875002" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.7375)"> <g transform="translate(72,-63.41)"> <text transform="matrix(1,0,0,-1,-71.95,63.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>。在丙肝病毒的存在<svg height="10.325" id="M25" style="vertical-align:-0.0pt;width:11.225px;" version="1.1" viewbox="0 0 11.225 10.325" width="11.225" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.325)"> <g transform="translate(72,-63.74)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>杀伤细胞繁殖病毒载量成正比<svg height="10.575" id="M26" style="vertical-align:-0.20064pt;width:12.625px;" version="1.1" viewbox="0 0 12.625 10.575" width="12.625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.575)"> <g transform="translate(72,-63.54)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>饱和率<svg height="14.7125" id="M27" style="vertical-align:-3.22282pt;width:97.75px;" version="1.1" viewbox="0 0 97.75 14.7125" width="97.75" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.7125)"> <g transform="translate(72,-60.23)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.97,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-58.26,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="4.1634989" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="13.190665" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="24.530886" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="31.407536" y="0"> /</tspan> <tspan style="font-size: 12.50px; " x="34.883369" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-16.5,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 米</tspan> <tspan style="font-size: 8.75px; " x="6.8090558" y="0"> 一个</tspan> <tspan style="font-size: 8.75px; " x="10.694944" y="0"> x</tspan> </text> <text transform="matrix(1,0,0,-1,1.99,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> )</tspan> </text> </g> </g> </svg>,在那里<svg height="14.475" id="M28" style="vertical-align:-3.13504pt;width:17.237499px;" version="1.1" viewbox="0 0 17.237499 14.475" width="17.237499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.475)"> <g transform="translate(72,-60.42)"> <text transform="matrix(1,0,0,-1,-71.95,63.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.97,60.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>是<svg height="10.325" id="M29" style="vertical-align:-0.0pt;width:11.225px;" version="1.1" viewbox="0 0 11.225 10.325" width="11.225" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.325)"> <g transform="translate(72,-63.74)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>细胞生长速度<svg height="14.35" id="M30" style="vertical-align:-3.22282pt;width:31.825001px;" version="1.1" viewbox="0 0 31.825001 14.35" width="31.825001" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.35)"> <g transform="translate(72,-60.52)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.07,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 米</tspan> <tspan style="font-size: 8.75px; " x="6.8090558" y="0"> 一个</tspan> <tspan style="font-size: 8.75px; " x="10.694944" y="0"> x</tspan> </text> </g> </g> </svg>可能的最大级别的吗<svg height="10.325" id="M31" style="vertical-align:-0.0pt;width:11.225px;" version="1.1" viewbox="0 0 11.225 10.325" width="11.225" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.325)"> <g transform="translate(72,-63.74)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>细胞群。此外,<svg height="10.325" id="M32" style="vertical-align:-0.0pt;width:11.225px;" version="1.1" viewbox="0 0 11.225 10.325" width="11.225" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.325)"> <g transform="translate(72,-63.74)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>细胞死亡在一个人均恒定速率<svg height="10.725" id="M33" style="vertical-align:-3.13504pt;width:18.0375px;" version="1.1" viewbox="0 0 18.0375 10.725" width="18.0375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.725)"> <g transform="translate(72,-63.42)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>。</p> <p>注意该地区<span class="equation" id="eq1"> <svg height="70.737503" id="M34" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 70.737503" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,70.7375)"> <g transform="translate(72,-15.41)"> <text transform="matrix(1,0,0,-1,50.8,40.58)"> <tspan style="font-size: 12.50px; " x="24.809999" y="-16.309999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="24.809999" y="-7.8499999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="24.809999" y="3.1900001"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="24.809999" y="14.23"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="24.809999" y="22.629999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="32.810001" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="38.66" y="-7.1054274e-015"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> <tspan style="font-size: 12.50px; " x="12.765563" y="0"> =</tspan> </text> <text transform="matrix(1,0,0,-1,100.38,37.45)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,104.73,40.58)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,120.85,37.45)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,124.07,40.58)"> <tspan style="font-size: 12.50px; " x="26.49" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.390473" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="17.604223" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="35.810001" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="47.837887" y="0"> R</tspan> </text> <text transform="matrix(1,0,0,-1,181.26,45.58)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 4</tspan> <tspan style="font-size: 8.75px; " x="0" y="8.1300001"> +</tspan> </text> <text transform="matrix(1,0,0,-1,189.84,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> |</tspan> <tspan style="font-size: 12.50px; " x="0" y="10.67"> |</tspan> <tspan style="font-size: 12.50px; " x="0" y="21.33"> |</tspan> <tspan style="font-size: 12.50px; " x="0" y="32"> |</tspan> <tspan style="font-size: 12.50px; " x="0" y="42.66"> |</tspan> <tspan style="font-size: 12.50px; " x="0" y="45.830002"> |</tspan> <tspan style="font-size: 12.50px; " x="5.4899998" y="4.8099999"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.204831" y="4.8099999"> =</tspan> <tspan style="font-size: 12.50px; " x="27.24522" y="4.8099999"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,228,55.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,235.83,58.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,258.78,55.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,268.86,58.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="19.092081" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="31.132469" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,310.92,55.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,317.61,58.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,340.56,55.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,195.33,41.21)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,206.24,38.08)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,213.37,41.21)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,235.63,38.08)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,242.32,41.21)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,265.27,38.08)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,275.36,41.21)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="9.364747" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="19.092081" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="31.132469" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="41.785027" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="53.825417" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,336.38,38.08)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,195.33,23.72)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="9.7148314" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="21.75522" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="32.107704" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="44.13559" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,246.35,20.59)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,354.83,56.89)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="8.46"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="19.5"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="30.540001"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="39"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="8" y="16.309999"> ,</tspan> <tspan style="font-size: 12.50px; " x="119.29" y="16.309999"> (</tspan> <tspan style="font-size: 12.50px; " x="123.4535" y="16.309999"> 2</tspan> <tspan style="font-size: 12.50px; " x="129.705" y="16.309999"> )</tspan> </text> </g> </g> </svg></span>在哪里<svg height="14.7125" id="M35" style="vertical-align:-3.2316pt;width:79.212502px;" version="1.1" viewbox="0 0 79.212502 14.7125" width="79.212502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.7125)"> <g transform="translate(72,-60.23)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-47.48,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-28.47,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-24.12,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> /</tspan> <tspan style="font-size: 12.50px; " x="3.4758339" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-13.03,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,<svg height="14.775" id="M36" style="vertical-align:-3.27548pt;width:108.6375px;" version="1.1" viewbox="0 0 108.6375 14.775" width="108.6375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.775)"> <g transform="translate(72,-60.18)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-51.21,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.040389" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="16.203888" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="22.317856" y="0"> /</tspan> <tspan style="font-size: 12.50px; " x="25.79369" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-17.8,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-10.3,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> )</tspan> <tspan style="font-size: 12.50px; " x="4.1634989" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,4.78,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,<svg height="16.549999" id="M37" style="vertical-align:-4.02643pt;width:112.075px;" version="1.1" viewbox="0 0 112.075 16.549999" width="112.075" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,16.55)"> <g transform="translate(72,-58.76)"> <text transform="matrix(1,0,0,-1,-71.95,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.07,59.7)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-51.52,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="16.191385" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-28.34,59.7)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-21.63,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> /</tspan> <tspan style="font-size: 12.50px; " x="3.4758339" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-10.54,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="0" y="9.0200005"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-3.83,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> )</tspan> <tspan style="font-size: 12.50px; " x="4.1634989" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,7.53,59.7)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,<svg height="16.549999" id="M38" style="vertical-align:-4.02643pt;width:158.1375px;" version="1.1" viewbox="0 0 158.1375 16.549999" width="158.1375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,16.55)"> <g transform="translate(72,-58.76)"> <text transform="matrix(1,0,0,-1,-71.95,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="0" y="9.0200005"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-54.15,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-34.5,59.7)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-25.01,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="15.50372" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-2.52,59.7)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,4.19,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> /</tspan> <tspan style="font-size: 12.50px; " x="3.4758339" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,14.54,59.7)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 米</tspan> <tspan style="font-size: 8.75px; " x="6.8090558" y="0"> 一个</tspan> <tspan style="font-size: 8.75px; " x="10.694944" y="0"> x</tspan> </text> <text transform="matrix(1,0,0,-1,33.03,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> )</tspan> <tspan style="font-size: 12.50px; " x="4.1634989" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,44.38,59.7)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>是积极不变子集系统(<一个href="#EEq3.1">1</一个>)。也就是说,每个解决方案的路径系统的初始条件<svg height="10.6875" id="M39" style="vertical-align:-0.0pt;width:11.75px;" version="1.1" viewbox="0 0 11.75 10.6875" width="11.75" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.6875)"> <g transform="translate(72,-63.45)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> </g> </g> </svg>将继续留在<svg height="10.6875" id="M40" style="vertical-align:-0.0pt;width:11.75px;" version="1.1" viewbox="0 0 11.75 10.6875" width="11.75" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.6875)"> <g transform="translate(72,-63.45)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> </g> </g> </svg>未来所有的时间。</p> <p>阈值参数的值<span class="equation" id="EEq3.2"> <svg height="37.137501" id="M41" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 37.137501" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,37.1375)"> <g transform="translate(72,-42.29)"> <text transform="matrix(1,0,0,-1,173.41,54.36)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,182.66,51.24)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,191.01,54.36)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="20.08" y="-9.2399998"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="26.856627" y="-9.2399998"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="32.970592" y="-9.2399998"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,230.95,60.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 204.24,57.49 37.91,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,204.24,45.61)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,211.85,42.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,215.07,45.61)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,222.69,42.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,227.04,45.61)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,234.65,42.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,474.12,54.02)"> <tspan style="font-size: 12.50px; " x="0" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="4.1634989" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="10.414999" y="0"> )</tspan> </text> </g> </g> </svg></span>这是名字<我>基本生殖病毒数量</我>过程中扮演着重要的角色,在全球的行为定性的分析系统的解决方案(<一个href="#EEq3.1">1</一个>)(即。,the disease evolution to the cure, or either to the chronic illness), clearly with relevant implications for the treatment of the hepatitis C.</p> <p>中央的结果如下。<span class="list"><span class="list-item"><span class="list-label">(1)</span><span class="list-content">如果<svg height="14.75" id="M42" style="vertical-align:-3.25793pt;width:44.987499px;" version="1.1" viewbox="0 0 44.987499 14.75" width="44.987499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>,那么系统(<一个href="#EEq3.1">1</一个>)有一个只容许平衡状态<svg height="10.6875" id="M43" style="vertical-align:-0.0pt;width:11.75px;" version="1.1" viewbox="0 0 11.75 10.6875" width="11.75" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.6875)"> <g transform="translate(72,-63.45)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> </g> </g> </svg>,微不足道的一个<svg height="14.75" id="M44" style="vertical-align:-3.25793pt;width:119.95px;" version="1.1" viewbox="0 0 119.95 14.75" width="119.95" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-57.6,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="16.191385" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-34.42,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-30.07,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> /</tspan> <tspan style="font-size: 12.50px; " x="3.4758339" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-18.98,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-14.63,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="11.452748" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="16.653996" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="22.905497" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="28.119247" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="34.370747" y="0"> )</tspan> </text> </g> </g> </svg>,这是全局渐近稳定的。该模型预测,没有感染的强度(即进口。,只是的价值<svg height="14.3875" id="M45" style="vertical-align:-3.25793pt;width:56.174999px;" version="1.1" viewbox="0 0 56.174999 14.3875" width="56.174999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-56.41,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-37.19,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>),受感染的个体,最终,永远都是健康的。</span></span><span class="list-item"><span class="list-label">(2)</span><span class="list-content">如果<svg height="14.75" id="M46" style="vertical-align:-3.25793pt;width:44.987499px;" version="1.1" viewbox="0 0 44.987499 14.75" width="44.987499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>,那么系统(<一个href="#EEq3.1">1</一个>)有两个容许平衡态:<span class="list"><span class="list-item"><span class="list-label">(我)</span><span class="list-content">微不足道的一个<svg height="14.75" id="M47" style="vertical-align:-3.25793pt;width:119.95px;" version="1.1" viewbox="0 0 119.95 14.75" width="119.95" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-57.6,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="16.191385" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-34.42,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-30.07,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> /</tspan> <tspan style="font-size: 12.50px; " x="3.4758339" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-18.98,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-14.63,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="11.452748" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="16.653996" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="22.905497" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="28.119247" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="34.370747" y="0"> )</tspan> </text> </g> </g> </svg>现在,这是不稳定的;</span></span><span class="list-item"><span class="list-label">(2)</span><span class="list-content">流行的(<svg height="11.9" id="M48" style="vertical-align:-0.30096pt;width:46.174999px;" version="1.1" viewbox="0 0 46.174999 11.9" width="46.174999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,11.9)"> <g transform="translate(72,-62.48)"> <text transform="matrix(1,0,0,-1,-71.95,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.95,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,-53.4,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> </text> </g> </g> </svg>)<span class="equation" id="eq2"> <svg height="38.575001" id="M49" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 38.575001" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,38.575)"> <g transform="translate(72,-41.14)"> <text transform="matrix(1,0,0,-1,87.24,53.45)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,93.24,50.32)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> <text transform="matrix(1,0,0,-1,101.59,53.45)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.04" y="7.3299999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="40.919998" y="-9.2299995"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,149.48,59.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 124.2,56.57 47.94,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,124.2,44.68)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="6.7766261" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,140.98,49.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,148.83,44.68)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,167.79,41.55)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,173.33,53.45)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="6.4099998" y="-9.2799997"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,187.35,59.6)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,194.85,62.73)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,204.86,67.73)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <g> <path d="m 179.74,56.57 30.19,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,191.78,44.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="19.35" y="-8.7600002"> ,</tspan> <tspan style="font-size: 12.50px; " x="24.551249" y="-8.7600002"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,226.34,58.45)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,231.41,53.45)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="20.629999" y="-9.2200003"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,259.02,59.55)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,265.73,62.67)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,272.61,59.55)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 米</tspan> <tspan style="font-size: 8.75px; " x="6.8090558" y="0"> 一个</tspan> <tspan style="font-size: 8.75px; " x="10.694944" y="0"> x</tspan> </text> <text transform="matrix(1,0,0,-1,289.64,62.67)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,299.64,67.67)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <g> <path d="m 237.82,56.57 81.12,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,237.82,44.68)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,244.8,41.55)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,251.51,44.68)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,261.51,49.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,269.36,44.68)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,288.32,41.55)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,295.03,44.68)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,301.91,41.55)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 米</tspan> <tspan style="font-size: 8.75px; " x="6.8090558" y="0"> 一个</tspan> <tspan style="font-size: 8.75px; " x="10.694944" y="0"> x</tspan> </text> <text transform="matrix(1,0,0,-1,320.13,46.12)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="153.99001" y="-7.3299999"> (</tspan> <tspan style="font-size: 12.50px; " x="158.1535" y="-7.3299999"> 4</tspan> <tspan style="font-size: 12.50px; " x="164.405" y="-7.3299999"> )</tspan> </text> </g> </g> </svg></span>全局渐近稳定和对应于丙型肝炎的流行病人此外,<svg height="14.7125" id="M50" style="vertical-align:-3.13504pt;width:80.400002px;" version="1.1" viewbox="0 0 80.400002 14.7125" width="80.400002" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.7125)"> <g transform="translate(72,-60.23)"> <text transform="matrix(1,0,0,-1,-71.95,63.41)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.28)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> <text transform="matrix(1,0,0,-1,-57.6,63.41)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="14.115887" y="0"> 我</tspan> <tspan style="font-size: 12.50px; " x="17.591721" y="0"> n</tspan> <tspan style="font-size: 12.50px; " x="23.843222" y="0"> t</tspan> <tspan style="font-size: 12.50px; " x="32.232735" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="36.396233" y="0"> O</tspan> <tspan style="font-size: 12.50px; " x="45.698463" y="0"> )</tspan> </text> </g> </g> </svg>如果<svg height="12.5" id="M51" style="vertical-align:-3.2316pt;width:48.012501px;" version="1.1" viewbox="0 0 48.012501 12.5" width="48.012501" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,12.5)"> <g transform="translate(72,-62)"> <text transform="matrix(1,0,0,-1,-71.95,65.27)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,62.15)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-57.64,65.27)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-37.99,62.15)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>。</span></span></span></span></span></span></p> <p>最后,它是非常重要的观察到免疫反应(即相关的参数。,<svg height="10.325" id="M52" style="vertical-align:-0.0pt;width:11.225px;" version="1.1" viewbox="0 0 11.225 10.325" width="11.225" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.325)"> <g transform="translate(72,-63.74)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>杀伤细胞)不存在阈值参数<svg height="14.3875" id="M53" style="vertical-align:-3.25793pt;width:17.7875px;" version="1.1" viewbox="0 0 17.7875 14.3875" width="17.7875" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>。出于这个原因,在接下来我们抑制我们的研究基本模型只有三个人口(健康的和不健康的肝细胞,病毒载量的丙肝病毒)。</p> <h4 id="dynamics-of-the-hepatitis-c:-reduced-model">4所示。丙型肝炎的动力学:减少模型</h4> <p>因为它只是上面提到的,只有六个十个参数的模型(<一个href="#EEq3.1">1</一个>)存在于阈值参数<svg height="14.3875" id="M54" style="vertical-align:-3.25793pt;width:17.7875px;" version="1.1" viewbox="0 0 17.7875 14.3875" width="17.7875" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>。另一方面,众所周知,免疫反应,原则上,在丙肝病毒感染的存在是低效的。然后,在下面,<svg height="10.325" id="M55" style="vertical-align:-0.0pt;width:11.225px;" version="1.1" viewbox="0 0 11.225 10.325" width="11.225" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.325)"> <g transform="translate(72,-63.74)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>杀手细胞群将不被考虑。因此,模型(<一个href="#EEq3.1">1</一个>)简化为以下之一:<span class="equation" id="EEq4.1"> <svg height="75.287498" id="M56" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 75.287498" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,75.2875)"> <g transform="translate(72,-11.77)"> <text transform="matrix(1,0,0,-1,154.96,64.17)"> <tspan style="font-size: 12.50px; " x="0" y="0"></tspan> <tspan style="font-size: 12.50px; " x="-10.51" y="2.53"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,155.37,58.51)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,163.19,61.64)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,182.21,58.51)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,189.33,61.64)"> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="18.116846" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,218.37,58.51)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,222.72,61.64)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="9.9523878" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="21.305113" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,251.64,58.51)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,255.99,61.64)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,266.91,58.51)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,271.26,61.64)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="-103.62" y="20.5"></tspan> <tspan style="font-size: 12.50px; " x="-114.15" y="23.040001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,168.03,35.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,175.89,38.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.040389" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="18.817015" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,205.62,35.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,209.97,38.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="9.9648914" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="21.305113" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,238.9,35.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,243.29,38.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,254.2,35.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,258.6,38.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="-84.550003" y="20.49"></tspan> <tspan style="font-size: 12.50px; " x="-92.43" y="23.030001"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="-78.951767" y="23.030001"> =</tspan> <tspan style="font-size: 12.50px; " x="-66.923882" y="23.030001"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="-60.809914" y="23.030001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,208.72,12.44)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,215.89,15.57)"> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,234.85,12.44)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,242.35,15.57)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="7.1892252" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="231.77" y="-23.190001"> (</tspan> <tspan style="font-size: 12.50px; " x="235.9335" y="-23.190001"> 5</tspan> <tspan style="font-size: 12.50px; " x="242.185" y="-23.190001"> )</tspan> </text> </g> </g> </svg></span></p> <p>这个基本模型,报道了丙型肝炎动力学(<一个href="#B17">9</一个>,<一个href="#B18">18</一个>- - - - - -- - - - - -- - - - - -- - - - - -- - - - - -- - - - - -<一个href="#B28">21</一个>),等等。在模型中所有参数都是正的。这是一个简单的问题来验证任何微分方程系统初值问题(<一个href="#EEq4.1">5</一个>)满足本地存在和唯一性定理的条件。</p> <p>在[<一个href="#B4">11</一个>),我们首先对集<span class="equation" id="eq3"> <svg height="48.1875" id="M57" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 48.1875" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,48.1875)"> <g transform="translate(72,-33.45)"> <text transform="matrix(1,0,0,-1,47.2,49.6)"> <tspan style="font-size: 12.50px; " x="24.82" y="9.7299995"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="38.27" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="44.119999" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> <tspan style="font-size: 12.50px; " x="12.778066" y="0"> =</tspan> </text> <text transform="matrix(1,0,0,-1,102.24,46.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,106.59,49.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,122.71,46.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,127.1,49.6)"> <tspan style="font-size: 12.50px; " x="15.22" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="24.540001" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="36.567886" y="0"> R</tspan> </text> <text transform="matrix(1,0,0,-1,173.02,54.6)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> <tspan style="font-size: 8.75px; " x="0" y="8.21"> +</tspan> </text> <text transform="matrix(1,0,0,-1,181.6,61.85)"> <tspan style="font-size: 12.50px; " x="0" y="0"> |</tspan> <tspan style="font-size: 12.50px; " x="0" y="10.66"> |</tspan> <tspan style="font-size: 12.50px; " x="0" y="21.33"> |</tspan> <tspan style="font-size: 12.50px; " x="0" y="24.49"> |</tspan> <tspan style="font-size: 12.50px; " x="5.48" y="2.8800001"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.207334" y="2.8800001"> =</tspan> <tspan style="font-size: 12.50px; " x="27.23522" y="2.8800001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,219.76,55.84)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,227.58,58.97)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.040389" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,250.54,55.84)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,260.62,58.97)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="9.364747" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="19.092081" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="31.132469" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,302.67,55.84)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,310.54,58.97)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,333.49,55.84)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,343.57,58.97)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="-156.49001" y="17.49"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,198,38.36)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,205.13,41.48)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,227.39,38.36)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,235.25,41.48)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,258.2,38.36)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,268.29,41.48)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="9.364747" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="19.092081" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="31.132469" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="41.797527" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="53.825417" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,329.32,38.36)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,350.88,39.87)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="15.54" y="-9.7299995"> ,</tspan> <tspan style="font-size: 12.50px; " x="123.24" y="-9.7299995"> (</tspan> <tspan style="font-size: 12.50px; " x="127.4035" y="-9.7299995"> 6</tspan> <tspan style="font-size: 12.50px; " x="133.655" y="-9.7299995"> )</tspan> </text> </g> </g> </svg></span>在哪里<svg height="14.7125" id="M58" style="vertical-align:-3.2316pt;width:79.212502px;" version="1.1" viewbox="0 0 79.212502 14.7125" width="79.212502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.7125)"> <g transform="translate(72,-60.23)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-47.48,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-28.47,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-24.12,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> /</tspan> <tspan style="font-size: 12.50px; " x="3.4758339" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-13.03,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>和<svg height="14.775" id="M59" style="vertical-align:-3.27548pt;width:108.6375px;" version="1.1" viewbox="0 0 108.6375 14.775" width="108.6375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.775)"> <g transform="translate(72,-60.18)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-51.21,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.040389" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="16.203888" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="22.317856" y="0"> /</tspan> <tspan style="font-size: 12.50px; " x="25.79369" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-17.8,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-10.3,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> )</tspan> <tspan style="font-size: 12.50px; " x="4.1634989" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,4.78,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>(见图<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig1/" target="_blank">1</一个>)。在这里,<svg height="14.2375" id="M60" style="vertical-align:-3.13504pt;width:26.375px;" version="1.1" viewbox="0 0 26.375 14.2375" width="26.375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.2375)"> <g transform="translate(72,-60.61)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>是可能的最大大小的人口健康的肝细胞在肝脏的健康个体,然后呢<svg height="14.2375" id="M61" style="vertical-align:-3.13504pt;width:21.7125px;" version="1.1" viewbox="0 0 21.7125 14.2375" width="21.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.2375)"> <g transform="translate(72,-60.61)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>是由病毒粒子最大数量在整个生命周期(即所有的肝细胞。,它是病毒最大负载,可以支持个人)。</p> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig1"> <div class="floats-partial-content fig-content-fig1"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.001" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.001.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图1</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig1/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="10.6875" id="M62" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 11.75 10.6875" width="11.75" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.6875)"> <g transform="translate(72,-63.45)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 我©</tspan> </text> </g> </g> </svg> <table> 集不变的是正的。</t一个ble> </div> </div> </div> <p><span class="statement" id="lem4.1"><span class="statement-title">引理1。</span><i>如果<svg height="13.675" id="M63" style="vertical-align:-3.2316pt;width:49.474998px;" version="1.1" viewbox="0 0 49.474998 13.675" width="49.474998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,13.675)"> <g transform="translate(72,-61.06)"> <text transform="matrix(1,0,0,-1,-71.95,64.34)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,61.21)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-56.47,64.34)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-36.82,61.21)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,然后<svg height="10.6875" id="M64" style="vertical-align:-0.0pt;width:11.75px;" version="1.1" viewbox="0 0 11.75 10.6875" width="11.75" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.6875)"> <g transform="translate(72,-63.45)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> </g> </g> </svg>是一个积极的不变子集<svg height="18.237499" id="M65" style="vertical-align:-3.57875pt;width:19.9125px;" version="1.1" viewbox="0 0 19.9125 18.237499" width="19.9125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,18.2375)"> <g transform="translate(72,-57.41)"> <text transform="matrix(1,0,0,-1,-71.95,61.03)"> <tspan style="font-size: 12.50px; " x="0" y="0"> R</tspan> </text> <text transform="matrix(1,0,0,-1,-62.61,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> <tspan style="font-size: 8.75px; " x="0" y="8.21"> +</tspan> </text> </g> </g> </svg>系统(<一个href="#EEq4.1">5</一个>)。</我></span></p> <p><span class="statement" id="proof1"><span class="statement-title"><i class="statement-title">证明。</我></span>是直接的验证向量场定义的系统(<一个href="#EEq4.1">5</一个>)不指向的外观<svg height="10.6875" id="M66" style="vertical-align:-0.0pt;width:11.75px;" version="1.1" viewbox="0 0 11.75 10.6875" width="11.75" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.6875)"> <g transform="translate(72,-63.45)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> </g> </g> </svg>,在其边界<svg height="10.8625" id="M67" style="vertical-align:-0.13794pt;width:19.737499px;" version="1.1" viewbox="0 0 19.737499 10.8625" width="19.737499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.8625)"> <g transform="translate(72,-63.31)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="6.3765302" y="0"> O</tspan> </text> </g> </g> </svg>。</span></p> <h5 id="sec4.1">4.1。平衡态</h5> <p>在本节中,我们表明,该系统(<一个href="#EEq4.1">5</一个>),两种可能的平衡态。其中一个没有病毒现在和对应于未受感染的平衡态(即。,the healthy individual), and another one has a positive constant virus load and corresponds to the endemically infected equilibrium state (i.e., to the chronic illness).</p> <p>系统的平衡态(<一个href="#EEq4.1">5</一个>)获得了解决代数方程系统:<span class="equation" id="EEq4.2"> <svg height="66.9375" id="M68" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 66.9375" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,66.9375)"> <g transform="translate(72,-18.45)"> <text transform="matrix(1,0,0,-1,148.96,63.2)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="9.7148314" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="21.75522" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,177.7,60.07)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,184.83,63.2)"> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.327718" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="18.104343" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,213.86,60.07)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,218.21,63.2)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="9.9648914" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="21.305113" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,247.14,60.07)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,251.49,63.2)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,262.4,60.07)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,266.75,63.2)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="-105.11" y="20.48"> 0</tspan> <tspan style="font-size: 12.50px; " x="-95.395172" y="20.48"> =</tspan> <tspan style="font-size: 12.50px; " x="-83.354782" y="20.48"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="-76.578156" y="20.48"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,201.09,39.6)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,205.44,42.72)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="9.9648914" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="21.305113" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,234.37,39.6)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,238.76,42.72)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,249.68,39.6)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,254.07,42.72)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="-86.019997" y="20.469999"> 0</tspan> <tspan style="font-size: 12.50px; " x="-76.305168" y="20.469999"> =</tspan> <tspan style="font-size: 12.50px; " x="-64.264778" y="20.469999"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="-58.150814" y="20.469999"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,206.84,19.13)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,214.01,22.25)"> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,232.97,19.13)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,240.47,22.25)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="7.1892252" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="233.64999" y="-19.85"> (</tspan> <tspan style="font-size: 12.50px; " x="237.81349" y="-19.85"> 7</tspan> <tspan style="font-size: 12.50px; " x="244.065" y="-19.85"> )</tspan> </text> </g> </g> </svg></span></p> <p>对于一个给定的<svg height="11.775" id="M69" style="vertical-align:-0.20064pt;width:18.975px;" version="1.1" viewbox="0 0 18.975 11.775" width="18.975" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,11.775)"> <g transform="translate(72,-62.58)"> <text transform="matrix(1,0,0,-1,-71.95,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.95,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> </g> </g> </svg>从第三个方程(<一个href="#EEq4.2">7</一个>),它遵循<span class="equation" id="EEq4.3"> <svg height="32.212502" id="M70" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 32.212502" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,32.2125)"> <g transform="translate(72,-46.23)"> <text transform="matrix(1,0,0,-1,174.21,57.32)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,186.25,62.32)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.13" y="8.1300001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,194.8,57.32)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="13.23" y="-9.2799997"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,215.64,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 208.03,60.44 15.11,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,212.53,48.57)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="11.81" y="-8.75"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,234.34,62.32)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,239.42,57.32)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="234.7" y="1.33"> (</tspan> <tspan style="font-size: 12.50px; " x="238.86349" y="1.33"> 8</tspan> <tspan style="font-size: 12.50px; " x="245.11501" y="1.33"> )</tspan> </text> </g> </g> </svg></span></p> <p>从第一个方程(<一个href="#EEq4.2">7</一个>),我们有<span class="equation" id="EEq4.4"> <svg height="37.099998" id="M71" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 37.099998" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,37.1)"> <g transform="translate(72,-42.32)"> <text transform="matrix(1,0,0,-1,165.33,54.36)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,177.37,59.36)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.12" y="8.1199999"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,185.92,54.36)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="31.540001" y="-9.2399998"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,224.44,60.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 199.16,57.49 47.94,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,199.16,45.59)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,206.77,42.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,213.9,45.59)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="18.116846" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,242.02,50.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,248.29,54.36)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="225.83" y="0.31999999"> (</tspan> <tspan style="font-size: 12.50px; " x="229.9935" y="0.31999999"> 9</tspan> <tspan style="font-size: 12.50px; " x="236.245" y="0.31999999"> )</tspan> </text> </g> </g> </svg></span></p> <p>用(<一个href="#EEq4.4">9</一个>)和(<一个href="#EEq4.3">8</一个>在第二个方程()<一个href="#EEq4.2">7</一个>),我们得到<span class="equation" id="EEq4.5"> <svg height="19.35" id="M72" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 19.35" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,19.35)"> <g transform="translate(72,-56.52)"> <text transform="matrix(1,0,0,-1,111.24,58.62)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="5.8499999" y="-2.51"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="11.963967" y="-2.51"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="18.740593" y="-2.51"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,136.96,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,144.09,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.327718" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,163.04,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,167.39,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,175.01,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,179.4,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,187.01,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,197.29,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="18.116846" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,223.03,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,227.42,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,235.03,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,242.53,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,252.54,66.14)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,257.61,58.62)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="7.9400001" y="-2.51"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,275.55,66.14)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,284.1,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="183.77" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="187.9335" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="194.185" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="200.43649" y="0"> )</tspan> </text> </g> </g> </svg></span></p> <p>如果<svg height="11.775" id="M73" style="vertical-align:-0.20064pt;width:46.174999px;" version="1.1" viewbox="0 0 46.174999 11.775" width="46.174999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,11.775)"> <g transform="translate(72,-62.58)"> <text transform="matrix(1,0,0,-1,-71.95,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.95,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,-53.4,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> </text> </g> </g> </svg>,从(<一个href="#EEq4.3">8</一个>)和(<一个href="#EEq4.4">9</一个>),然后接下去<svg height="15.5625" id="M74" style="vertical-align:-3.2316pt;width:48.724998px;" version="1.1" viewbox="0 0 48.724998 15.5625" width="48.724998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,15.5625)"> <g transform="translate(72,-59.55)"> <text transform="matrix(1,0,0,-1,-71.95,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-59.91,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.12" y="8.1300001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-51.36,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> </text> </g> </g> </svg>和<svg height="15.5625" id="M75" style="vertical-align:-3.2316pt;width:74.362503px;" version="1.1" viewbox="0 0 74.362503 15.5625" width="74.362503" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,15.5625)"> <g transform="translate(72,-59.55)"> <text transform="matrix(1,0,0,-1,-71.95,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-59.91,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.12" y="8.1300001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-51.36,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-32.35,59.7)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-28,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> /</tspan> <tspan style="font-size: 12.50px; " x="3.4758339" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-16.91,59.7)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>。因此,<span class="equation" id="eq4"> <svg height="38.575001" id="M76" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 38.575001" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,38.575)"> <g transform="translate(72,-41.14)"> <text transform="matrix(1,0,0,-1,167.17,53.45)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,173.17,50.32)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,181.52,53.45)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.03" y="7.3299999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="22.92" y="-9.2299995"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,211.42,59.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 204.13,56.57 11.96,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,204.13,44.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,211.74,41.57)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,217.28,53.45)"> <tspan style="font-size: 12.50px; " x="22.93" y="7.3299999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2137508" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="11.465251" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="16.666498" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="250.59" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="254.75349" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="261.005" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="267.2565" y="0"> )</tspan> </text> </g> </g> </svg></span>是一种均衡的状态(<一个href="#EEq4.1">5</一个>)。这种状态对应于健康或不被感染的个体。导致的结果是,所有的肝细胞健康,和<svg height="15.5625" id="M77" style="vertical-align:-3.2316pt;width:74.362503px;" version="1.1" viewbox="0 0 74.362503 15.5625" width="74.362503" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,15.5625)"> <g transform="translate(72,-59.55)"> <text transform="matrix(1,0,0,-1,-71.95,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-59.91,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.12" y="8.1300001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-51.36,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-32.35,59.7)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-28,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> /</tspan> <tspan style="font-size: 12.50px; " x="3.4758339" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-16.91,59.7)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>平均最大数量的细胞在肝脏健康的个体。</p> <p>为<svg height="11.9" id="M78" style="vertical-align:-0.30096pt;width:46.174999px;" version="1.1" viewbox="0 0 46.174999 11.9" width="46.174999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,11.9)"> <g transform="translate(72,-62.48)"> <text transform="matrix(1,0,0,-1,-71.95,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.95,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,-53.4,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> </text> </g> </g> </svg>,从(<一个href="#EEq4.5">10</一个>),一个获得:<span class="equation" id="EEq4.6"> <svg height="29.475" id="M79" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 29.475" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,29.475)"> <g transform="translate(72,-48.42)"> <text transform="matrix(1,0,0,-1,159.16,57.36)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,169.16,62.36)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,177.71,57.36)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="13.23" y="-9.2399998"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,198.55,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 190.94,60.49 11.96,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,193.53,48.61)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.65" y="-6.2399998"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="18.5" y="-8.75"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,221.29,54.24)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,228.94,57.36)"> <tspan style="font-size: 12.50px; " x="17.59" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="25.530001" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="238.92999" y="0.27000001"> (</tspan> <tspan style="font-size: 12.50px; " x="243.09351" y="0.27000001"> 1</tspan> <tspan style="font-size: 12.50px; " x="249.345" y="0.27000001"> 2</tspan> <tspan style="font-size: 12.50px; " x="255.5965" y="0.27000001"> )</tspan> </text> </g> </g> </svg></span>在哪里<span class="equation" id="eq5"> <svg height="37.137501" id="M80" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 37.137501" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,37.1375)"> <g transform="translate(72,-42.29)"> <text transform="matrix(1,0,0,-1,172.82,54.36)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,182.07,51.24)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,190.42,54.36)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="20.67" y="-9.2399998"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="27.446627" y="-9.2399998"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="33.560593" y="-9.2399998"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,230.95,60.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 203.65,57.49 39.09,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,203.65,45.61)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,211.27,42.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,215.66,45.61)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,223.27,42.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,227.62,45.61)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,235.24,42.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,467.87,54.02)"> <tspan style="font-size: 12.50px; " x="0" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="4.1634989" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="10.414999" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="16.666498" y="0"> )</tspan> </text> </g> </g> </svg></span>是相同的阈值参数中引入[<一个href="#B4">11</一个>]。</p> <p>很明显,<svg height="11.9" id="M81" style="vertical-align:-0.30096pt;width:46.174999px;" version="1.1" viewbox="0 0 46.174999 11.9" width="46.174999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,11.9)"> <g transform="translate(72,-62.48)"> <text transform="matrix(1,0,0,-1,-71.95,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.95,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,-53.4,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> </text> </g> </g> </svg>当且仅当<svg height="14.75" id="M82" style="vertical-align:-3.25793pt;width:44.987499px;" version="1.1" viewbox="0 0 44.987499 14.75" width="44.987499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>。</p> <p>替换<svg height="11.775" id="M83" style="vertical-align:-0.20064pt;width:18.975px;" version="1.1" viewbox="0 0 18.975 11.775" width="18.975" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,11.775)"> <g transform="translate(72,-62.58)"> <text transform="matrix(1,0,0,-1,-71.95,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.95,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> </g> </g> </svg>由(<一个href="#EEq4.6">12</一个>)(<一个href="#EEq4.3">8</一个>)和(<一个href="#EEq4.4">9</一个>),它遵循<span class="equation" id="eq6"> <svg height="37.112499" id="M84" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 37.112499" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,37.1125)"> <g transform="translate(72,-42.31)"> <text transform="matrix(1,0,0,-1,107.93,54.36)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,119.97,59.36)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.12" y="8.1199999"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,128.52,54.36)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="20.639999" y="-9.2399998"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,156.13,60.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 141.75,57.49 26.14,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,141.75,45.61)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,149.37,42.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,153.76,45.61)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,163.01,42.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,171.17,51.85)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="5.8499999" y="-2.51"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,186.27,51.24)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,193.92,54.36)"> <tspan style="font-size: 12.50px; " x="17.6" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="25.530001" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="50.66103" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,256.63,59.36)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.13" y="8.1199999"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,265.18,54.36)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="20.610001" y="-9.2399998"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,292.77,60.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 278.41,57.49 26.09,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,278.41,45.61)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,286.02,42.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,290.37,45.61)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,299.63,42.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,305.7,54.03)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="162.17" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="166.3335" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="172.58499" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="178.8365" y="0"> )</tspan> </text> </g> </g> </svg></span></p> <p>因此,第二个系统的平衡态(<一个href="#EEq4.1">5</一个>)是<span class="equation" id="EEq4.7"> <svg height="38.575001" id="M85" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 38.575001" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,38.575)"> <g transform="translate(72,-41.14)"> <text transform="matrix(1,0,0,-1,95.59,53.45)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,101.59,50.32)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> <text transform="matrix(1,0,0,-1,109.94,53.45)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.03" y="7.3299999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="29.99" y="-9.2299995"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,146.91,59.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 132.55,56.57 26.09,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,132.55,44.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,140.16,41.57)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,144.51,44.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,153.76,41.57)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,159.83,53.45)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="13.81" y="-9.2299995"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,180.62,59.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 166.24,56.57 26.13,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,166.24,44.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,173.85,41.57)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,178.24,44.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,187.5,41.57)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,195.65,50.93)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="5.8499999" y="-2.52"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,210.75,50.32)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,218.41,53.45)"> <tspan style="font-size: 12.50px; " x="17.59" y="2.52"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="25.530001" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="31.93" y="-9.2299995"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.327718" y="0"> 1</tspan> </text> <text transform="matrix(1,0,0,-1,257.96,59.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 250.34,56.57 11.97,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,252.94,44.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.64" y="-6.2399998"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="18.5" y="-8.7600002"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,280.69,50.32)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,288.34,53.45)"> <tspan style="font-size: 12.50px; " x="17.6" y="2.52"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="23.450001" y="7.3299999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="179.53" y="7.1054274e-015"> (</tspan> <tspan style="font-size: 12.50px; " x="183.6935" y="7.1054274e-015"> 1</tspan> <tspan style="font-size: 12.50px; " x="189.94499" y="7.1054274e-015"> 5</tspan> <tspan style="font-size: 12.50px; " x="196.1965" y="7.1054274e-015"> )</tspan> </text> </g> </g> </svg></span>这是平衡态对应特有耐心,当且仅当吗<svg height="14.75" id="M86" style="vertical-align:-3.25793pt;width:44.987499px;" version="1.1" viewbox="0 0 44.987499 14.75" width="44.987499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>。</p> <p><span class="statement" id="thm4.1"><span class="statement-title">定理2。</span><i>假设<svg height="13.675" id="M87" style="vertical-align:-3.2316pt;width:49.474998px;" version="1.1" viewbox="0 0 49.474998 13.675" width="49.474998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,13.675)"> <g transform="translate(72,-61.06)"> <text transform="matrix(1,0,0,-1,-71.95,64.34)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,61.21)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-56.47,64.34)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-36.82,61.21)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>:</我><span class="list"><span class="list-item"><span class="list-label">(我)</span><span class="list-content"><i>如果<svg height="14.75" id="M88" style="vertical-align:-3.25793pt;width:44.987499px;" version="1.1" viewbox="0 0 44.987499 14.75" width="44.987499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>,然后<svg height="14.3875" id="M89" style="vertical-align:-3.25793pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.3875" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>是唯一的平衡态<svg height="10.6875" id="M90" style="vertical-align:-0.0pt;width:11.75px;" version="1.1" viewbox="0 0 11.75 10.6875" width="11.75" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.6875)"> <g transform="translate(72,-63.45)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> </g> </g> </svg>,</我></span></span><span class="list-item"><span class="list-label">(2)</span><span class="list-content"><i>如果<svg height="14.75" id="M91" style="vertical-align:-3.25793pt;width:44.987499px;" version="1.1" viewbox="0 0 44.987499 14.75" width="44.987499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>,那么系统(<一个href="#EEq4.1">5</一个>)有两个平衡点<svg height="10.6875" id="M92" style="vertical-align:-0.0pt;width:11.75px;" version="1.1" viewbox="0 0 11.75 10.6875" width="11.75" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.6875)"> <g transform="translate(72,-63.45)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> </g> </g> </svg>:简单的<svg height="14.3875" id="M93" style="vertical-align:-3.25793pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.3875" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>和地方性地感染状态<svg height="14.2375" id="M94" style="vertical-align:-3.13504pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.2375" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.2375)"> <g transform="translate(72,-60.61)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> </g> </g> </svg>。</我></span></span></span><i></i></span></p> <p><span class="statement" id="proof2"><span class="statement-title"><i class="statement-title">证明。</我></span>显然如果<svg height="14.75" id="M95" style="vertical-align:-3.25793pt;width:44.987499px;" version="1.1" viewbox="0 0 44.987499 14.75" width="44.987499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>然后<svg height="14.2375" id="M96" style="vertical-align:-3.13504pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.2375" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.2375)"> <g transform="translate(72,-60.61)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> </g> </g> </svg>减少到<svg height="14.3875" id="M97" style="vertical-align:-3.25793pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.3875" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>。如果<svg height="14.75" id="M98" style="vertical-align:-3.25793pt;width:44.987499px;" version="1.1" viewbox="0 0 44.987499 14.75" width="44.987499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> <</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>,然后<svg height="14.6" id="M99" style="vertical-align:-3.13504pt;width:44.737499px;" version="1.1" viewbox="0 0 44.737499 14.6" width="44.737499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.6)"> <g transform="translate(72,-60.32)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> <text transform="matrix(1,0,0,-1,-57.6,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> O</tspan> </text> </g> </g> </svg>。这<svg height="14.3875" id="M100" style="vertical-align:-3.25793pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.3875" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>是唯一一个平衡态<svg height="10.6875" id="M101" style="vertical-align:-0.0pt;width:11.75px;" version="1.1" viewbox="0 0 11.75 10.6875" width="11.75" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.6875)"> <g transform="translate(72,-63.45)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> </g> </g> </svg>。现在,如果<svg height="10.8375" id="M102" style="vertical-align:-3.2316pt;width:49.474998px;" version="1.1" viewbox="0 0 49.474998 10.8375" width="49.474998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.8375)"> <g transform="translate(72,-63.33)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-56.47,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-36.82,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>然后<svg height="15.5625" id="M103" style="vertical-align:-3.2316pt;width:106.2px;" version="1.1" viewbox="0 0 106.2 15.5625" width="106.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,15.5625)"> <g transform="translate(72,-59.55)"> <text transform="matrix(1,0,0,-1,-71.95,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-59.91,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.12" y="8.1300001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-52.06,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-28.67,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.13" y="8.1300001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-20.12,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,2.83,59.7)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,如果<svg height="12.5" id="M104" style="vertical-align:-3.2316pt;width:49.474998px;" version="1.1" viewbox="0 0 49.474998 12.5" width="49.474998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,12.5)"> <g transform="translate(72,-62)"> <text transform="matrix(1,0,0,-1,-71.95,65.27)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,62.15)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-56.47,65.27)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-36.82,62.15)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>然后<svg height="14.7125" id="M105" style="vertical-align:-3.2316pt;width:88.837502px;" version="1.1" viewbox="0 0 88.837502 14.7125" width="88.837502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.7125)"> <g transform="translate(72,-60.23)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="9.7148314" y="0"> <</tspan> <tspan style="font-size: 12.50px; " x="21.75522" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-42.57,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-38.22,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> /</tspan> <tspan style="font-size: 12.50px; " x="3.4758339" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-27.13,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-19.27,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> <</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>,因此我们有<svg height="15.5625" id="M106" style="vertical-align:-3.2316pt;width:106.2px;" version="1.1" viewbox="0 0 106.2 15.5625" width="106.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,15.5625)"> <g transform="translate(72,-59.55)"> <text transform="matrix(1,0,0,-1,-71.95,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-59.91,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.12" y="8.1300001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-52.06,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-28.67,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.13" y="8.1300001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-20.12,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> <</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,2.83,59.7)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>。在任何情况下,<svg height="15.5625" id="M107" style="vertical-align:-3.2316pt;width:106.2px;" version="1.1" viewbox="0 0 106.2 15.5625" width="106.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,15.5625)"> <g transform="translate(72,-59.55)"> <text transform="matrix(1,0,0,-1,-71.95,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-59.91,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.12" y="8.1300001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-52.06,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-28.67,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.13" y="8.1300001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-20.12,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,2.83,59.7)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>。所以,自<svg height="14.775" id="M108" style="vertical-align:-3.27548pt;width:108.6375px;" version="1.1" viewbox="0 0 108.6375 14.775" width="108.6375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.775)"> <g transform="translate(72,-60.18)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-51.21,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.040389" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="16.203888" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="22.317856" y="0"> /</tspan> <tspan style="font-size: 12.50px; " x="25.79369" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-17.8,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-10.3,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> )</tspan> <tspan style="font-size: 12.50px; " x="4.1634989" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,4.78,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>和<svg height="14.75" id="M109" style="vertical-align:-3.25793pt;width:44.987499px;" version="1.1" viewbox="0 0 44.987499 14.75" width="44.987499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>,它意味着<svg height="15.4375" id="M110" style="vertical-align:-3.13504pt;width:59.950001px;" version="1.1" viewbox="0 0 59.950001 15.4375" width="59.950001" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,15.4375)"> <g transform="translate(72,-59.65)"> <text transform="matrix(1,0,0,-1,-71.95,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.95,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,-53.4,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> <</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-34.17,59.7)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>。</span></p> <h5 id="sec4.2">4.2。平衡态的稳定性分析</h5> <p>在下面,我们研究了稳定平衡态对应的属性<我>健康的</我>个人和<我>地方性地</我>被感染的病人。</p> <h6 id="sec4.2.1">4.2.1。准备的稳定性<svg height="14.3875" id="M111" style="vertical-align:-3.25793pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.3875" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg></h6> <p>当地的平衡态的稳定性<svg height="14.3875" id="M112" style="vertical-align:-3.25793pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.3875" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>是由矩阵的特征值<span class="equation" id="eq7"> <svg height="94.012497" id="M113" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 94.012497" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,94.0125)"> <g transform="translate(72,3.21)"> <text transform="matrix(1,0,0,-1,137.16,31.27)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="10.34" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="16.190001" y="3.5527137e-015"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,159.35,28.15)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,164.22,28.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="9.3299999" y="-2.51"> =</tspan> <tspan style="font-size: 12.50px; " x="21.370001" y="-28.129999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="21.370001" y="-16.610001"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="21.370001" y="-5.0799999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="21.370001" y="6.4400001"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="21.370001" y="17.959999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="21.370001" y="29.43"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="26.99" y="-25.6"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="35.554554" y="-25.6"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,207.39,51.24)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,224.88,54.36)"> <tspan style="font-size: 12.50px; " x="36.240002" y="-9.2399998"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="19.37965" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="27.944204" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,268.1,60.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 260.8,57.49 11.97,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,260.8,45.61)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,268.42,42.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,198.35,23.06)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="19.367147" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="27.931702" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,233.9,19.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,248.55,23.06)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="8.29" y="-9.2399998"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,263.82,29.17)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 256.52,26.19 11.97,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,256.52,14.31)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,264.14,11.18)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,198.35,0.59)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="26.593882" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="48.92424" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="57.488792" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,263.46,-2.53)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,273.96,56.89)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="11.52"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="23.049999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="34.57"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="46.09"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="57.560001"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="193.91" y="25.620001"> (</tspan> <tspan style="font-size: 12.50px; " x="198.0735" y="25.620001"> 1</tspan> <tspan style="font-size: 12.50px; " x="204.325" y="25.620001"> 6</tspan> <tspan style="font-size: 12.50px; " x="210.57649" y="25.620001"> )</tspan> </text> </g> </g> </svg></span>直接显示<svg height="14.3875" id="M114" style="vertical-align:-3.25793pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.3875" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>局部渐近稳定当且仅当吗<svg height="14.75" id="M115" style="vertical-align:-3.25793pt;width:44.987499px;" version="1.1" viewbox="0 0 44.987499 14.75" width="44.987499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> <</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>。</p> <p>证明<svg height="14.3875" id="M116" style="vertical-align:-3.25793pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.3875" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>全局渐近稳定在吗<svg height="10.6875" id="M117" style="vertical-align:-0.0pt;width:11.75px;" version="1.1" viewbox="0 0 11.75 10.6875" width="11.75" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.6875)"> <g transform="translate(72,-63.45)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> </g> </g> </svg>,因为<svg height="14.75" id="M118" style="vertical-align:-3.25793pt;width:44.987499px;" version="1.1" viewbox="0 0 44.987499 14.75" width="44.987499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>,我们使用第二La Salle定理(<一个href="#B15">22</一个>):如果<svg height="14.125" id="M119" style="vertical-align:-2.34499pt;width:83.199997px;" version="1.1" viewbox="0 0 83.199997 14.125" width="83.199997" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.125)"> <g transform="translate(72,-60.7)"> <text transform="matrix(1,0,0,-1,-71.95,63.09)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="10.402496" y="0"> :</tspan> <tspan style="font-size: 12.50px; " x="20.267363" y="0"> O</tspan> <tspan style="font-size: 12.50px; " x="35.120926" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="52.262539" y="0"> R</tspan> </text> <text transform="matrix(1,0,0,-1,-10.34,68.09)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>是连续的和局部李普希茨,<svg height="11.625" id="M120" style="vertical-align:-0.33858pt;width:48.875px;" version="1.1" viewbox="0 0 48.875 11.625" width="48.875" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,11.625)"> <g transform="translate(72,-62.7)"> <text transform="matrix(1,0,0,-1,-71.95,63.09)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> <tspan style="font-size: 12.50px; " x="12.765563" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="24.805952" y="0"> R</tspan> </text> <text transform="matrix(1,0,0,-1,-37.8,68.09)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>开放,如果<svg height="10.8875" id="M121" style="vertical-align:-0.16302pt;width:79.474998px;" version="1.1" viewbox="0 0 79.474998 10.8875" width="79.474998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.8875)"> <g transform="translate(72,-63.29)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.277946" y="0"> :</tspan> <tspan style="font-size: 12.50px; " x="22.142813" y="0"> O</tspan> <tspan style="font-size: 12.50px; " x="36.996376" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="54.137989" y="0"> R</tspan> </text> </g> </g> </svg>是这样的,<svg height="16.5375" id="M122" style="vertical-align:-2.21957pt;width:70.400002px;" version="1.1" viewbox="0 0 70.400002 16.5375" width="70.400002" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,16.5375)"> <g transform="translate(72,-58.77)"> <text transform="matrix(1,0,0,-1,-71.95,61.03)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.277946" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="24.318335" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-38.23,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> <text transform="matrix(1,0,0,-1,-33.36,61.03)"> <tspan style="font-size: 12.50px; " x="0" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="4.1634989" y="0"> O</tspan> <tspan style="font-size: 12.50px; " x="13.465731" y="0"> )</tspan> </text> </g> </g> </svg>,<svg height="12.3" id="M123" style="vertical-align:-1.29163pt;width:38.349998px;" version="1.1" viewbox="0 0 38.349998 12.3" width="38.349998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,12.3)"> <g transform="translate(72,-62.16)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.277946" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="24.318335" y="0"> 0</tspan> </text> </g> </g> </svg>在<svg height="10.6875" id="M124" style="vertical-align:-0.0pt;width:11.75px;" version="1.1" viewbox="0 0 11.75 10.6875" width="11.75" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.6875)"> <g transform="translate(72,-63.45)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> </g> </g> </svg>和它的导数<svg height="14.625" id="M125" style="vertical-align:-1.29163pt;width:40.0625px;" version="1.1" viewbox="0 0 40.0625 14.625" width="40.0625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.625)"> <g transform="translate(72,-60.3)"> <text transform="matrix(1,0,0,-1,-63.98,64.17)"> <tspan style="font-size: 12.50px; " x="0" y="0"></tspan> <tspan style="font-size: 12.50px; " x="-7.9699998" y="2.53"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="5.6832762" y="2.53"> =</tspan> <tspan style="font-size: 12.50px; " x="17.723665" y="2.53"> 0</tspan> </text> </g> </g> </svg>在解决路径<svg height="13.6125" id="M126" style="vertical-align:-2.34499pt;width:54.099998px;" version="1.1" viewbox="0 0 54.099998 13.6125" width="54.099998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,13.6125)"> <g transform="translate(72,-61.11)"> <text transform="matrix(1,0,0,-1,-65.09,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"></tspan> <tspan style="font-size: 12.50px; " x="-6.851644" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="2.813175" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="14.841061" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="21.780226" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="25.943726" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="32.145214" y="0"> )</tspan> </text> </g> </g> </svg>在<svg height="10.6875" id="M127" style="vertical-align:-0.0pt;width:11.75px;" version="1.1" viewbox="0 0 11.75 10.6875" width="11.75" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.6875)"> <g transform="translate(72,-63.45)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> </g> </g> </svg>;然后一组<svg height="7.1875" id="M128" style="vertical-align:-0.13794pt;width:10.7625px;" version="1.1" viewbox="0 0 10.7625 7.1875" width="10.7625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,7.1875)"> <g transform="translate(72,-66.25)"> <text transform="matrix(1,0,0,-1,-71.95,66.44)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>限制,如果它存在,每一个解决方案的路径<svg height="13.6125" id="M129" style="vertical-align:-2.34499pt;width:54.099998px;" version="1.1" viewbox="0 0 54.099998 13.6125" width="54.099998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,13.6125)"> <g transform="translate(72,-61.11)"> <text transform="matrix(1,0,0,-1,-65.09,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"></tspan> <tspan style="font-size: 12.50px; " x="-6.851644" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="2.813175" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="14.841061" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="21.780226" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="25.943726" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="32.145214" y="0"> )</tspan> </text> </g> </g> </svg>包含在一组<svg height="17.075001" id="M130" style="vertical-align:-3.25793pt;width:165.77499px;" version="1.1" viewbox="0 0 165.77499 17.075001" width="165.77499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,17.075)"> <g transform="translate(72,-58.34)"> <text transform="matrix(1,0,0,-1,-71.95,61.64)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> <text transform="matrix(1,0,0,-1,-62.65,58.51)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.3,61.64)"> <tspan style="font-size: 12.50px; " x="70.360001" y="-2.53"></tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> {</tspan> <tspan style="font-size: 12.50px; " x="18.029325" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="27.706648" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="39.747036" y="0"> O</tspan> <tspan style="font-size: 12.50px; " x="52.525105" y="0"> :</tspan> <tspan style="font-size: 12.50px; " x="62.389999" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="72.567444" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="76.730942" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="82.932426" y="0"> )</tspan> <tspan style="font-size: 12.50px; " x="90.571762" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="102.61215" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="108.86365" y="0"> }</tspan> </text> </g> </g> </svg>。</p> <p>现在,在<一个href="#B4">11</一个>),我们考虑系统(<一个href="#EEq4.1">5</一个>)以下Lyapunov-La Salle函数<svg height="15.05" id="M131" style="vertical-align:-3.49493pt;width:87.599998px;" version="1.1" viewbox="0 0 87.599998 15.05" width="87.599998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,15.05)"> <g transform="translate(72,-59.96)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.277946" y="0"> :</tspan> <tspan style="font-size: 12.50px; " x="22.142813" y="0"> O</tspan> <tspan style="font-size: 12.50px; " x="36.996376" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="54.137989" y="0"> R</tspan> </text> <text transform="matrix(1,0,0,-1,-8.47,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> +</tspan> </text> </g> </g> </svg>,由<span class="equation" id="eq8"> <svg height="19.35" id="M132" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 19.35" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,19.35)"> <g transform="translate(72,-56.52)"> <text transform="matrix(1,0,0,-1,134.2,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.28" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="18.129999" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,163.24,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,167.59,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,183.72,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,188.11,61.13)"> <tspan style="font-size: 12.50px; " x="15.21" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="24.540001" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="36.567886" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="42.681854" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,241.71,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,248.88,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,267.84,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,272.23,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="7.1892252" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="195.64" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="199.8035" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="206.05499" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="212.3065" y="0"> )</tspan> </text> </g> </g> </svg></span>很明显,<svg height="16.5375" id="M133" style="vertical-align:-2.21957pt;width:70.400002px;" version="1.1" viewbox="0 0 70.400002 16.5375" width="70.400002" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,16.5375)"> <g transform="translate(72,-58.77)"> <text transform="matrix(1,0,0,-1,-71.95,61.03)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.277946" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="24.318335" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-38.23,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> <text transform="matrix(1,0,0,-1,-33.36,61.03)"> <tspan style="font-size: 12.50px; " x="0" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="4.1634989" y="0"> O</tspan> <tspan style="font-size: 12.50px; " x="13.465731" y="0"> )</tspan> </text> </g> </g> </svg>和<svg height="14.7125" id="M134" style="vertical-align:-3.2316pt;width:108.975px;" version="1.1" viewbox="0 0 108.975 14.7125" width="108.975" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.7125)"> <g transform="translate(72,-60.23)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="8.8146152" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="12.978114" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-48.06,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-43.71,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-27.58,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-23.19,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.390473" y="0"> )</tspan> <tspan style="font-size: 12.50px; " x="20.029806" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="32.070194" y="0"> 0</tspan> </text> </g> </g> </svg>,每<svg height="14.7125" id="M135" style="vertical-align:-3.2316pt;width:101.775px;" version="1.1" viewbox="0 0 101.775 14.7125" width="101.775" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.7125)"> <g transform="translate(72,-60.23)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="4.1634989" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-56.87,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-52.52,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-36.4,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-32,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.390473" y="0"> )</tspan> <tspan style="font-size: 12.50px; " x="20.029806" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="32.057693" y="0"> O</tspan> </text> </g> </g> </svg>。和直接观察,如果<svg height="14.75" id="M136" style="vertical-align:-3.25793pt;width:44.987499px;" version="1.1" viewbox="0 0 44.987499 14.75" width="44.987499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>的导数,<svg height="10.5375" id="M137" style="vertical-align:-0.16302pt;width:12.8625px;" version="1.1" viewbox="0 0 12.8625 10.5375" width="12.8625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.5375)"> <g transform="translate(72,-63.57)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>非负解路径的系统(<一个href="#EEq4.1">5</一个>)<svg height="10.6875" id="M138" style="vertical-align:-0.0pt;width:11.75px;" version="1.1" viewbox="0 0 11.75 10.6875" width="11.75" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.6875)"> <g transform="translate(72,-63.45)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> </g> </g> </svg>。所以,La Salle定理的<svg height="7.1875" id="M139" style="vertical-align:-0.13794pt;width:10.7625px;" version="1.1" viewbox="0 0 10.7625 7.1875" width="10.7625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,7.1875)"> <g transform="translate(72,-66.25)"> <text transform="matrix(1,0,0,-1,-71.95,66.44)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>限制设置为每个解决方案的系统(<一个href="#EEq4.1">5</一个>)与初始条件<svg height="13.5625" id="M140" style="vertical-align:-2.21957pt;width:44.8125px;" version="1.1" viewbox="0 0 44.8125 13.5625" width="44.8125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,13.5625)"> <g transform="translate(72,-61.15)"> <text transform="matrix(1,0,0,-1,-71.95,63.41)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 我</tspan> <tspan style="font-size: 12.50px; " x="3.4758339" y="0"> n</tspan> <tspan style="font-size: 12.50px; " x="9.727334" y="0"> t</tspan> <tspan style="font-size: 12.50px; " x="18.116846" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="22.280346" y="0"> O</tspan> <tspan style="font-size: 12.50px; " x="31.582579" y="0"> )</tspan> </text> </g> </g> </svg>是的一个子集<span class="equation" id="eq9"> <svg height="19.35" id="M141" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 19.35" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,19.35)"> <g transform="translate(72,-56.52)"> <text transform="matrix(1,0,0,-1,84.95,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> <text transform="matrix(1,0,0,-1,94.25,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,102.6,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="25.08" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.04" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="19.229225" y="2.51"> 吗?</tspan> </text> <text transform="matrix(1,0,0,-1,138.59,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,142.94,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,159.07,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,163.46,61.13)"> <tspan style="font-size: 12.50px; " x="15.21" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="67.18" y="-2.54"></tspan> <tspan style="font-size: 12.50px; " x="59.209999" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="71.480003" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="77.339996" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="24.540001" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="36.567886" y="0"> O</tspan> <tspan style="font-size: 12.50px; " x="49.345951" y="0"> :</tspan> </text> <text transform="matrix(1,0,0,-1,251.71,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,256.06,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,272.19,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,276.58,61.13)"> <tspan style="font-size: 12.50px; " x="15.21" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="42.82" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="24.530001" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="36.570389" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="52.099998" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="191.28999" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="195.45351" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="201.705" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="207.9565" y="0"> )</tspan> </text> </g> </g> </svg></span></p> <p><span class="statement" id="head1"><span class="statement-title"><i class="statement-title">肯定</我></span><br>如果<svg height="14.75" id="M142" style="vertical-align:-3.25793pt;width:44.987499px;" version="1.1" viewbox="0 0 44.987499 14.75" width="44.987499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>,每个解决方案的系统(<一个href="#EEq4.1">5</一个>)与初始条件<svg height="14.75" id="M143" style="vertical-align:-3.25793pt;width:17.85px;" version="1.1" viewbox="0 0 17.85 14.75" width="17.85" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> <text transform="matrix(1,0,0,-1,-62.65,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>渐近收敛于琐碎的平衡状态<svg height="14.3875" id="M144" style="vertical-align:-3.25793pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.3875" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg><i>。</我></span></p> <p>以下证明。</p> <p><span class="statement" id="thm4.2"><span class="statement-title">定理3。</span><i>如果<svg height="13.675" id="M145" style="vertical-align:-3.2316pt;width:49.474998px;" version="1.1" viewbox="0 0 49.474998 13.675" width="49.474998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,13.675)"> <g transform="translate(72,-61.06)"> <text transform="matrix(1,0,0,-1,-71.95,64.34)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,61.21)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-56.47,64.34)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-36.82,61.21)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>和<svg height="14.75" id="M146" style="vertical-align:-3.25793pt;width:44.987499px;" version="1.1" viewbox="0 0 44.987499 14.75" width="44.987499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>,然后<svg height="14.3875" id="M147" style="vertical-align:-3.25793pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.3875" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>是<svg height="10.6875" id="M148" style="vertical-align:-0.0pt;width:11.75px;" version="1.1" viewbox="0 0 11.75 10.6875" width="11.75" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.6875)"> <g transform="translate(72,-63.45)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> </g> </g> </svg>全局渐近平衡态。</我></span></p> <h6 id="sec4.2.2">4.2.2。的稳定性<svg height="14.2375" id="M149" style="vertical-align:-3.13504pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.2375" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.2375)"> <g transform="translate(72,-60.61)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> </g> </g> </svg></h6> <p>雅可比矩阵的病态的感染的平衡状态<svg height="14.2375" id="M150" style="vertical-align:-3.13504pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.2375" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.2375)"> <g transform="translate(72,-60.61)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> </g> </g> </svg>是<span class="equation" id="eq10"> <svg height="94.012497" id="M151" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 94.012497" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,94.0125)"> <g transform="translate(72,3.21)"> <text transform="matrix(1,0,0,-1,113.63,31.27)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="10.33" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="16.18" y="3.5527137e-015"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,135.81,28.15)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> <text transform="matrix(1,0,0,-1,140.69,28.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="9.3199997" y="-2.51"> =</tspan> <tspan style="font-size: 12.50px; " x="21.360001" y="-28.129999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="21.360001" y="-16.610001"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="21.360001" y="-5.0799999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="21.360001" y="6.4400001"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="21.360001" y="17.959999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="21.360001" y="29.43"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="39.779999" y="-25.6"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="48.344555" y="-25.6"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,196.65,51.24)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,201,54.36)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,210.26,51.24)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,241.06,54.36)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="19.392153" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="33.150002" y="-9.2399998"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="39.926624" y="-9.2399998"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,287.96,60.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 270.21,57.49 26.09,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,270.21,45.61)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,277.83,42.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,282.18,45.61)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,291.43,42.48)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,167.68,23.06)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,175.29,19.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,181.72,20.55)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="5.8600001" y="-2.51"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,196.83,19.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,204.48,23.06)"> <tspan style="font-size: 12.50px; " x="17.6" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="29.42" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="37.984554" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,250.08,19.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,269.93,32.3)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="6.7766261" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,283.68,29.17)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 265.93,26.19 26.09,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,265.93,14.31)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,273.55,11.18)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,277.9,14.31)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,287.15,11.18)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,194.68,0.59)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="46.450001" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="72.456238" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="81.020798" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,283.32,-2.53)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,297.5,56.89)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="11.52"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="23.049999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="34.57"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="46.09"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="57.560001"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="170.37" y="25.620001"> (</tspan> <tspan style="font-size: 12.50px; " x="174.53349" y="25.620001"> 1</tspan> <tspan style="font-size: 12.50px; " x="180.785" y="25.620001"> 9</tspan> <tspan style="font-size: 12.50px; " x="187.0365" y="25.620001"> )</tspan> </text> </g> </g> </svg></span>及其相关特征多项式<span class="equation" id="eq11"> <svg height="18.549999" id="M152" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 18.549999" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,18.55)"> <g transform="translate(72,-57.16)"> <text transform="matrix(1,0,0,-1,125.45,60.96)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="8.1899996" y="-0.0099999998"> (</tspan> <tspan style="font-size: 12.50px; " x="12.353499" y="-0.0099999998"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="19.117622" y="-0.0099999998"> )</tspan> <tspan style="font-size: 12.50px; " x="26.756954" y="-0.0099999998"> =</tspan> <tspan style="font-size: 12.50px; " x="38.78484" y="-0.0099999998"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,171.01,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> <text transform="matrix(1,0,0,-1,178.66,60.96)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.35" y="-0.0099999998"> (</tspan> <tspan style="font-size: 12.50px; " x="15.513499" y="-0.0099999998"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="24.553167" y="-0.0099999998"> +</tspan> <tspan style="font-size: 12.50px; " x="35.905891" y="-0.0099999998"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="41.782303" y="-0.0099999998"> )</tspan> <tspan style="font-size: 12.50px; " x="48.021297" y="-0.0099999998"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,233.46,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 2</tspan> </text> <text transform="matrix(1,0,0,-1,241.11,60.96)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="17.616728" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="23.493137" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="33.032925" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="44.373146" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="226.75999" y="-0.5"> (</tspan> <tspan style="font-size: 12.50px; " x="230.92349" y="-0.5"> 2</tspan> <tspan style="font-size: 12.50px; " x="237.175" y="-0.5"> 0</tspan> <tspan style="font-size: 12.50px; " x="243.4265" y="-0.5"> )</tspan> </text> </g> </g> </svg></span>与<span class="equation" id="EEq4.8"> <svg height="71.775002" id="M153" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 71.775002" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,71.775)"> <g transform="translate(72,-14.58)"> <text transform="matrix(1,0,0,-1,173.03,63.2)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="9.7523403" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="21.780226" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,202.44,60.07)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,206.79,63.2)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,216.04,60.07)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,224.39,63.2)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="-58.73" y="20.48"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="-49.390259" y="20.48"> =</tspan> <tspan style="font-size: 12.50px; " x="-37.349869" y="20.48"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,194.66,39.6)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,201.83,42.72)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,220.79,39.6)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,231.76,42.72)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="-78.980003" y="23.530001"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="-70.327927" y="23.530001"> =</tspan> <tspan style="font-size: 12.50px; " x="-58.287537" y="23.530001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,181.09,16.07)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,185.48,19.19)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,193.1,16.07)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,197.45,19.19)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,205.06,16.07)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,214.65,16.68)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="5.8499999" y="-2.51"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,229.75,16.07)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,237.4,19.19)"> <tspan style="font-size: 12.50px; " x="17.6" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="25.530001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="230.47" y="-20.969999"> (</tspan> <tspan style="font-size: 12.50px; " x="234.6335" y="-20.969999"> 2</tspan> <tspan style="font-size: 12.50px; " x="240.88499" y="-20.969999"> 1</tspan> <tspan style="font-size: 12.50px; " x="247.13651" y="-20.969999"> )</tspan> </text> </g> </g> </svg></span></p> <p>使用Routh-Hurwitz标准[<一个href="#B9">23</一个>),当地的地方病平衡点的稳定性<svg height="14.2375" id="M154" style="vertical-align:-3.13504pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.2375" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.2375)"> <g transform="translate(72,-60.61)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> </g> </g> </svg>建立了。事实上,注意<span class="equation" id="eq12"> <svg height="135.96249" id="M155" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 135.96249" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,135.9625)"> <g transform="translate(72,36.77)"> <text transform="matrix(1,0,0,-1,133.98,63.2)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> </text> <text transform="matrix(1,0,0,-1,143,60.07)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> <text transform="matrix(1,0,0,-1,151.35,63.2)"> <tspan style="font-size: 12.50px; " x="-41.709999" y="31.219999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> d</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> e</tspan> <tspan style="font-size: 12.50px; " x="23.830717" y="0"> t</tspan> <tspan style="font-size: 12.50px; " x="32.232735" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="36.396233" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="45.448406" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="56.788628" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="62.665035" y="0"> )</tspan> <tspan style="font-size: 12.50px; " x="70.304367" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="82.344757" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="91.396927" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="102.73715" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="112.08939" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="124.12978" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="130.38129" y="0"> ,</tspan> </text> <text transform="matrix(1,0,0,-1,118.67,28.85)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 2</tspan> </text> <text transform="matrix(1,0,0,-1,127.02,31.98)"> <tspan style="font-size: 12.50px; " x="32.23" y="7.3299999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="86.010002" y="7.3299999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="-16.42" y="48.09"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> d</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> e</tspan> <tspan style="font-size: 12.50px; " x="23.830717" y="0"> t</tspan> <tspan style="font-size: 12.50px; " x="41.610001" y="-9.3599997"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="50.64967" y="-9.3599997"> +</tspan> <tspan style="font-size: 12.50px; " x="62.002392" y="-9.3599997"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="76.805946" y="-9.3599997"> 1</tspan> <tspan style="font-size: 12.50px; " x="51.84" y="8.1199999"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="73.85778" y="8.1199999"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="80.134293" y="8.1199999"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="98.860001" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="110.88789" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="115.05138" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="124.11606" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="135.45628" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="141.33269" y="0"> )</tspan> <tspan style="font-size: 12.50px; " x="147.5842" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="153.8607" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="162.51277" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="173.853" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="179.04173" y="0"> ,</tspan> </text> <text transform="matrix(1,0,0,-1,119.63,-19.23)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> <text transform="matrix(1,0,0,-1,127.98,-16.11)"> <tspan style="font-size: 12.50px; " x="32.23" y="-12.95"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="32.23" y="-2.1900001"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="32.23" y="8.5600004"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="32.23" y="19.25"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="114.51" y="-12.95"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="114.51" y="-2.1900001"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="114.51" y="8.5600004"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="114.51" y="19.25"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> d</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> e</tspan> <tspan style="font-size: 12.50px; " x="23.830717" y="0"> t</tspan> <tspan style="font-size: 12.50px; " x="37.860001" y="-18.110001"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="46.89967" y="-18.110001"> +</tspan> <tspan style="font-size: 12.50px; " x="58.252392" y="-18.110001"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="73.055946" y="-18.110001"> 1</tspan> <tspan style="font-size: 12.50px; " x="98.249489" y="-18.110001"> 0</tspan> <tspan style="font-size: 12.50px; " x="48.09" y="-0.63"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="70.10778" y="-0.63"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="76.384293" y="-0.63"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="88.237129" y="-0.63"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="97.289307" y="-0.63"> +</tspan> <tspan style="font-size: 12.50px; " x="108.62952" y="-0.63"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="47.869999" y="16.85"> 0</tspan> <tspan style="font-size: 12.50px; " x="73.051041" y="16.85"> 0</tspan> <tspan style="font-size: 12.50px; " x="98.457138" y="16.85"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="123.61" y="-7.1054274e-015"> =</tspan> <tspan style="font-size: 12.50px; " x="135.65039" y="-7.1054274e-015"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="141.46428" y="-7.1054274e-015"> 吗?</tspan> </text> <text transform="matrix(1,0,0,-1,278.47,-19.23)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 2</tspan> </text> <text transform="matrix(1,0,0,-1,286.82,-16.11)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="181.05" y="-30.6"> (</tspan> <tspan style="font-size: 12.50px; " x="185.2135" y="-30.6"> 2</tspan> <tspan style="font-size: 12.50px; " x="191.465" y="-30.6"> 2</tspan> <tspan style="font-size: 12.50px; " x="197.71649" y="-30.6"> )</tspan> </text> </g> </g> </svg></span></p> <p>从(<一个href="#EEq4.8">21</一个>),如果<svg height="14.75" id="M156" style="vertical-align:-3.25793pt;width:44.987499px;" version="1.1" viewbox="0 0 44.987499 14.75" width="44.987499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>然后<svg height="11.0625" id="M157" style="vertical-align:-0.30096pt;width:33.8125px;" version="1.1" viewbox="0 0 33.8125 11.0625" width="33.8125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,11.0625)"> <g transform="translate(72,-63.15)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="8.6520758" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="20.692465" y="0"> 0</tspan> </text> </g> </g> </svg>。此外,我们也有<span class="equation" id="eq13"> <svg height="49.912498" id="M158" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 49.912498" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,49.9125)"> <g transform="translate(72,-32.07)"> <text transform="matrix(1,0,0,-1,53.4,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> </text> <text transform="matrix(1,0,0,-1,62.42,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 2</tspan> </text> <text transform="matrix(1,0,0,-1,70.77,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.04" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="17.889999" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,96.27,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,100.62,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,109.88,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,117.53,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,136.49,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,143.66,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,162.62,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,170.12,58.62)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="7.9299998" y="-2.51"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,185.66,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,190.01,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,199.27,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,206.22,58.62)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="5.8600001" y="-2.51"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,219.69,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,226.86,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,245.82,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,253.32,58.62)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="8.6300001" y="-2.51"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="19.970221" y="-2.51"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,280.91,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,285.3,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,292.91,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,297.26,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,304.88,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,314.46,58.62)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="5.8499999" y="-2.51"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,329.56,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,337.22,61.13)"> <tspan style="font-size: 12.50px; " x="17.59" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="-266.45001" y="24.440001"> =</tspan> <tspan style="font-size: 12.50px; " x="-254.41" y="26.959999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="-248.56" y="24.440001"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.327718" y="0"> 1</tspan> </text> <text transform="matrix(1,0,0,-1,96.27,33.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,100.62,36.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,109.88,33.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,117.53,36.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,136.49,33.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,140.88,34.17)"> <tspan style="font-size: 12.50px; " x="13.79" y="-2.52"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="7.9269018" y="0"> 吗?</tspan> </text> <text transform="matrix(1,0,0,-1,162.28,33.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,169.45,36.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,188.41,33.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,195.91,34.17)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="7.9299998" y="-2.52"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,211.46,33.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,215.81,36.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,225.06,33.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,232.71,36.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,251.67,33.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,256.02,36.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,263.63,41.69)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 2</tspan> <tspan style="font-size: 8.75px; " x="0" y="9.0200005"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,271.13,36.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,280.39,33.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,288.04,36.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,307,33.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,311.39,36.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,319,33.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,323.35,36.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,330.97,33.56)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,341.94,36.69)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="125.93" y="-12.22"> (</tspan> <tspan style="font-size: 12.50px; " x="130.09351" y="-12.22"> 2</tspan> <tspan style="font-size: 12.50px; " x="136.345" y="-12.22"> 3</tspan> <tspan style="font-size: 12.50px; " x="142.5965" y="-12.22"> )</tspan> </text> </g> </g> </svg></span></p> <p>证明的全局渐近稳定性<svg height="14.2375" id="M159" style="vertical-align:-3.13504pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.2375" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.2375)"> <g transform="translate(72,-60.61)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> </g> </g> </svg>在<svg height="10.6875" id="M160" style="vertical-align:-0.0pt;width:11.75px;" version="1.1" viewbox="0 0 11.75 10.6875" width="11.75" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.6875)"> <g transform="translate(72,-63.45)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> </g> </g> </svg>再次,我们使用拉萨尔的定理,阐述在前面的小节。但是现在,(后<一个href="#B14">24</一个>),我们开始考虑以下Lyapunov-La Salle函数<svg height="15.05" id="M161" style="vertical-align:-3.49493pt;width:87.599998px;" version="1.1" viewbox="0 0 87.599998 15.05" width="87.599998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,15.05)"> <g transform="translate(72,-59.96)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.277946" y="0"> :</tspan> <tspan style="font-size: 12.50px; " x="22.142813" y="0"> O</tspan> <tspan style="font-size: 12.50px; " x="36.996376" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="54.137989" y="0"> R</tspan> </text> <text transform="matrix(1,0,0,-1,-8.47,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> +</tspan> </text> </g> </g> </svg>:<span class="equation" id="eq14"> <svg height="81.137497" id="M162" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 81.137497" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,81.1375)"> <g transform="translate(72,-7.09)"> <text transform="matrix(1,0,0,-1,76.15,54.55)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.27" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="18.120001" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,105.19,51.42)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,109.54,54.55)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,125.66,51.42)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,130.06,54.55)"> <tspan style="font-size: 12.50px; " x="15.21" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="24.530001" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="36.557884" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,177.55,51.42)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,184.67,54.55)"> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,208.06,59.55)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.13" y="8.1300001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,215.22,54.55)"> <tspan style="font-size: 12.50px; " x="13.93" y="-9.2399998"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> l</tspan> <tspan style="font-size: 12.50px; " x="3.4758339" y="0"> n</tspan> </text> <text transform="matrix(1,0,0,-1,240.06,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 228.22,57.68 17.12,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,228.22,45.78)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,240.26,50.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.12" y="8"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,249.31,54.55)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,271.57,51.42)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,278.74,54.55)"> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,302.13,59.55)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.13" y="8.1300001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,309.28,54.55)"> <tspan style="font-size: 12.50px; " x="13.92" y="-9.2399998"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> l</tspan> <tspan style="font-size: 12.50px; " x="3.4758339" y="0"> n</tspan> </text> <text transform="matrix(1,0,0,-1,334.11,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 322.29,57.68 17.12,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,322.29,45.78)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,334.33,50.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.12" y="8"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,163.86,18.18)"> <tspan style="font-size: 12.50px; " x="0" y="0"> +</tspan> <tspan style="font-size: 12.50px; " x="12.54" y="-9.2299995"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,184.01,24.29)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <g> <path d="m 176.4,21.3 12.01,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,179.35,9.43)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.34" y="-3.8299999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="19.700001" y="-8.75"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="29.66489" y="-8.75"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="41.005112" y="-8.75"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,230.36,23.18)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,237.52,18.18)"> <tspan style="font-size: 12.50px; " x="15.55" y="-7.25"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> l</tspan> <tspan style="font-size: 12.50px; " x="3.4758339" y="0"> n</tspan> </text> <g> <path d="m 250.53,21.3 15.08,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,250.53,9.41)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,260.53,14.29)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,266.8,13.26)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="9.6899996" y="-4.9200001"> 。</tspan> <tspan style="font-size: 12.50px; " x="201.07001" y="-23.16"> (</tspan> <tspan style="font-size: 12.50px; " x="205.23351" y="-23.16"> 2</tspan> <tspan style="font-size: 12.50px; " x="211.485" y="-23.16"> 4</tspan> <tspan style="font-size: 12.50px; " x="217.7365" y="-23.16"> )</tspan> </text> </g> </g> </svg></span></p> <p>很明显<svg height="16.5375" id="M163" style="vertical-align:-2.21957pt;width:70.400002px;" version="1.1" viewbox="0 0 70.400002 16.5375" width="70.400002" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,16.5375)"> <g transform="translate(72,-58.77)"> <text transform="matrix(1,0,0,-1,-71.95,61.03)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.277946" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="24.318335" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-38.23,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> <text transform="matrix(1,0,0,-1,-33.36,61.03)"> <tspan style="font-size: 12.50px; " x="0" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="4.1634989" y="0"> O</tspan> <tspan style="font-size: 12.50px; " x="13.465731" y="0"> )</tspan> </text> </g> </g> </svg>,<svg height="14.7125" id="M164" style="vertical-align:-3.2316pt;width:108.975px;" version="1.1" viewbox="0 0 108.975 14.7125" width="108.975" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.7125)"> <g transform="translate(72,-60.23)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="8.8146152" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="12.978114" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-48.06,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-43.71,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-27.58,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-23.19,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.390473" y="0"> )</tspan> <tspan style="font-size: 12.50px; " x="20.029806" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="32.070194" y="0"> 0</tspan> </text> </g> </g> </svg>对于每一个<svg height="14.7125" id="M165" style="vertical-align:-3.2316pt;width:87.550003px;" version="1.1" viewbox="0 0 87.550003 14.7125" width="87.550003" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.7125)"> <g transform="translate(72,-60.23)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-56.69,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-40.56,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-36.17,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="15.866307" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="27.906696" y="0"> 0</tspan> </text> </g> </g> </svg>。此外,如果<svg height="14.75" id="M166" style="vertical-align:-3.25793pt;width:44.987499px;" version="1.1" viewbox="0 0 44.987499 14.75" width="44.987499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>,你可以检查<svg height="13.225" id="M167" style="vertical-align:-0.16302pt;width:12.8625px;" version="1.1" viewbox="0 0 12.8625 13.225" width="12.8625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,13.225)"> <g transform="translate(72,-61.42)"> <text transform="matrix(1,0,0,-1,-63.98,64.17)"> <tspan style="font-size: 12.50px; " x="0" y="0"></tspan> <tspan style="font-size: 12.50px; " x="-7.9699998" y="2.53"> ? ?</tspan> </text> </g> </g> </svg>非负的<svg height="13.5625" id="M168" style="vertical-align:-2.21957pt;width:44.8125px;" version="1.1" viewbox="0 0 44.8125 13.5625" width="44.8125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,13.5625)"> <g transform="translate(72,-61.15)"> <text transform="matrix(1,0,0,-1,-71.95,63.41)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 我</tspan> <tspan style="font-size: 12.50px; " x="3.4758339" y="0"> n</tspan> <tspan style="font-size: 12.50px; " x="9.727334" y="0"> t</tspan> <tspan style="font-size: 12.50px; " x="18.116846" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="22.280346" y="0"> O</tspan> <tspan style="font-size: 12.50px; " x="31.582579" y="0"> )</tspan> </text> </g> </g> </svg>(详细信息请参阅[<一个href="#B14">24</一个>])。然后,通过La Salle定理,<svg height="7.1875" id="M169" style="vertical-align:-0.13794pt;width:10.7625px;" version="1.1" viewbox="0 0 10.7625 7.1875" width="10.7625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,7.1875)"> <g transform="translate(72,-66.25)"> <text transform="matrix(1,0,0,-1,-71.95,66.44)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>限制设置为每个解决方案的系统(<一个href="#EEq4.1">5</一个>)与初始条件<svg height="13.5625" id="M170" style="vertical-align:-2.21957pt;width:44.8125px;" version="1.1" viewbox="0 0 44.8125 13.5625" width="44.8125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,13.5625)"> <g transform="translate(72,-61.15)"> <text transform="matrix(1,0,0,-1,-71.95,63.41)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 我</tspan> <tspan style="font-size: 12.50px; " x="3.4758339" y="0"> n</tspan> <tspan style="font-size: 12.50px; " x="9.727334" y="0"> t</tspan> <tspan style="font-size: 12.50px; " x="18.116846" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="22.280346" y="0"> O</tspan> <tspan style="font-size: 12.50px; " x="31.582579" y="0"> )</tspan> </text> </g> </g> </svg>是的一个子集<span class="equation" id="eq15"> <svg height="49.775002" id="M171" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 49.775002" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,49.775)"> <g transform="translate(72,-32.18)"> <text transform="matrix(1,0,0,-1,73.29,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> O</tspan> </text> <text transform="matrix(1,0,0,-1,82.59,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,90.94,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="25.08" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="12.03" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="19.219225" y="2.51"> 吗?</tspan> </text> <text transform="matrix(1,0,0,-1,126.93,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,131.28,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,147.4,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,151.8,61.13)"> <tspan style="font-size: 12.50px; " x="15.21" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="95.709999" y="-2.54"></tspan> <tspan style="font-size: 12.50px; " x="87.739998" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="100.02" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="105.87" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="24.530001" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="38.645885" y="0"> 我</tspan> <tspan style="font-size: 12.50px; " x="42.121719" y="0"> n</tspan> <tspan style="font-size: 12.50px; " x="48.373222" y="0"> t</tspan> <tspan style="font-size: 12.50px; " x="56.779999" y="-0.0099999998"> (</tspan> <tspan style="font-size: 12.50px; " x="60.943501" y="-0.0099999998"> O</tspan> <tspan style="font-size: 12.50px; " x="70.245728" y="-0.0099999998"> )</tspan> <tspan style="font-size: 12.50px; " x="77.872559" y="-0.0099999998"> :</tspan> </text> <text transform="matrix(1,0,0,-1,268.58,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,272.93,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,289.06,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,293.45,61.13)"> <tspan style="font-size: 12.50px; " x="15.21" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="42.82" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="-203" y="24.34"> =</tspan> <tspan style="font-size: 12.50px; " x="-177.92" y="24.34"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="24.540001" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="36.567886" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="-190.96001" y="26.85"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="-183.77078" y="26.85"> 吗?</tspan> </text> <text transform="matrix(1,0,0,-1,127.57,41.79)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.12" y="8.1300001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,132.65,36.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,149.9,41.79)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="-1.13" y="8.1300001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,154.97,36.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,170.18,41.79)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,175.26,34.28)"> <tspan style="font-size: 12.50px; " x="16.030001" y="-2.51"> 。</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="5.8514042" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="292.60999" y="-14.68"> (</tspan> <tspan style="font-size: 12.50px; " x="296.7735" y="-14.68"> 2</tspan> <tspan style="font-size: 12.50px; " x="303.02499" y="-14.68"> 5</tspan> <tspan style="font-size: 12.50px; " x="309.27649" y="-14.68"> )</tspan> </text> </g> </g> </svg></span>总之,我们有以下。</p> <p><span class="statement" id="thm4.3"><span class="statement-title">定理4。</span><i>假设<svg height="13.675" id="M172" style="vertical-align:-3.2316pt;width:49.474998px;" version="1.1" viewbox="0 0 49.474998 13.675" width="49.474998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,13.675)"> <g transform="translate(72,-61.06)"> <text transform="matrix(1,0,0,-1,-71.95,64.34)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,61.21)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-56.47,64.34)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-36.82,61.21)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,如果<svg height="14.75" id="M173" style="vertical-align:-3.25793pt;width:44.987499px;" version="1.1" viewbox="0 0 44.987499 14.75" width="44.987499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> </text> </g> </g> </svg>然后<svg height="14.2375" id="M174" style="vertical-align:-3.13504pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.2375" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.2375)"> <g transform="translate(72,-60.61)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> </g> </g> </svg>是全局渐近平衡态,<svg height="14.3875" id="M175" style="vertical-align:-3.25793pt;width:13.725px;" version="1.1" viewbox="0 0 13.725 14.3875" width="13.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.95,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>现在是一个双曲平衡态。</我></span></p> <h4 id="numerical-comparison-between-the-models">5。数值模型之间的比较</h4> <p>在本节中,数值结果报告(<一个href="#B4">11</一个>)与相应的给出的简化模型研究了以前在上一节。在这种比较,我们使用相同的初始条件和参数值(<一个href="#B17">9</一个>,<一个href="#B4">11</一个>,<一个href="#B18">18</一个>,<一个href="#B1">25</一个>,<一个href="#B3">26</一个>]。其他数值模拟进行了和报道<一个href="#B1">25</一个>- - - - - -- - - - - -- - - - - -- - - - - -- - - - - -- - - - - -<一个href="#B2">27</一个>]。在与初始种群,众所周知,<svg height="14.7875" id="M176" style="vertical-align:-3.13504pt;width:77.012497px;" version="1.1" viewbox="0 0 77.012497 14.7875" width="77.012497" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.7875)"> <g transform="translate(72,-60.17)"> <text transform="matrix(1,0,0,-1,-71.95,63.35)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.22)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-47.48,63.35)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="24.530886" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="30.782387" y="0"> 0</tspan> </text> </g> </g> </svg>细胞/毫米<sup>3</sup>是指肝细胞人口健康的个体,它是合理的考虑,10%的肝细胞最初感染,所以呢<svg height="14.9375" id="M177" style="vertical-align:-3.25793pt;width:75.324997px;" version="1.1" viewbox="0 0 75.324997 14.9375" width="75.324997" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.9375)"> <g transform="translate(72,-60.05)"> <text transform="matrix(1,0,0,-1,-71.95,63.35)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.22)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-48.84,63.35)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.040389" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="18.291889" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="24.543388" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="30.794889" y="0"> 0</tspan> </text> </g> </g> </svg>细胞/毫米<sup>3</sup>,<svg height="14.9375" id="M178" style="vertical-align:-3.25793pt;width:67.5625px;" version="1.1" viewbox="0 0 67.5625 14.9375" width="67.5625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.9375)"> <g transform="translate(72,-60.05)"> <text transform="matrix(1,0,0,-1,-71.95,63.35)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.22)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-48.79,63.35)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="24.530886" y="0"> 0</tspan> </text> </g> </g> </svg>细胞/毫米<sup>3</sup>。和<svg height="14.75" id="M179" style="vertical-align:-3.25793pt;width:58.037498px;" version="1.1" viewbox="0 0 58.037498 14.75" width="58.037498" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-56.41,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="24.530886" y="0"> 0</tspan> </text> </g> </g> </svg>UI / ?<我>µ</我>L和<svg height="14.75" id="M180" style="vertical-align:-3.25793pt;width:57.650002px;" version="1.1" viewbox="0 0 57.650002 14.75" width="57.650002" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.07,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-56.73,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.040389" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="18.291889" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="24.543388" y="0"> 0</tspan> </text> </g> </g> </svg>细胞/毫米<sup>3</sup>low-infection案例也合理值。</p> <p>初始条件是<span class="equation" id="EEq5.1"> <svg height="16.5375" id="M181" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 16.5375" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,16.5375)"> <g transform="translate(72,-58.77)"> <text transform="matrix(1,0,0,-1,139.86,63.2)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,146.07,60.07)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,154.41,63.2)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.040389" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="16.203888" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="22.455387" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="28.706888" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="34.958389" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="41.209888" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="46.411137" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="52.662636" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="58.914135" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="65.165634" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="70.379387" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="76.63089" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="82.882385" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="89.133888" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="94.347641" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="100.59914" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="106.85064" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="113.10213" y="0"> )</tspan> <tspan style="font-size: 12.50px; " x="119.34113" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="313.45999" y="0.63"> (</tspan> <tspan style="font-size: 12.50px; " x="317.6235" y="0.63"> 2</tspan> <tspan style="font-size: 12.50px; " x="323.875" y="0.63"> 6</tspan> <tspan style="font-size: 12.50px; " x="330.1265" y="0.63"> )</tspan> </text> </g> </g> </svg></span></p> <p>容许的参数向量模型(<一个href="#EEq3.1">1</一个>)作为<span class="equation" id="eq16"> <svg height="19.35" id="M182" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 19.35" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,19.35)"> <g transform="translate(72,-56.52)"> <text transform="matrix(1,0,0,-1,104.69,61.13)"> <tspan style="font-size: 12.50px; " x="22.059999" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="27.91" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="10.014903" y="0"> =</tspan> </text> <text transform="matrix(1,0,0,-1,139.58,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,143.93,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="11.977874" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="17.191626" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,168.74,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,173.09,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,185.91,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,190.31,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="11.315215" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="16.516462" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,214.45,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,221.95,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="11.490257" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="16.704008" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,245.64,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,252.35,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,265.17,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,271.89,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,283.97,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 米</tspan> <tspan style="font-size: 8.75px; " x="6.8090558" y="0"> 一个</tspan> <tspan style="font-size: 8.75px; " x="10.694944" y="0"> x</tspan> </text> <text transform="matrix(1,0,0,-1,301,58.62)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="7.9400001" y="-2.51"> 。</tspan> <tspan style="font-size: 12.50px; " x="166.87" y="-2.51"> (</tspan> <tspan style="font-size: 12.50px; " x="171.03349" y="-2.51"> 2</tspan> <tspan style="font-size: 12.50px; " x="177.285" y="-2.51"> 7</tspan> <tspan style="font-size: 12.50px; " x="183.5365" y="-2.51"> )</tspan> </text> </g> </g> </svg></span></p> <p><span class="statement" id="casee1"><span class="statement-title"><i class="statement-title">例1(治愈)。</我></span>比较数值的进化行为两种模型获得的解决方案在讨论中,我们使用以下参数值:<span class="equation" id="eq17"> <svg height="50.587502" id="M183" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 50.587502" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,50.5875)"> <g transform="translate(72,-31.53)"> <text transform="matrix(1,0,0,-1,92.13,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,98.68,65.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,107.23,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.04" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="17.889999" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="24.1415" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="30.393" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="36.644501" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="41.845749" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="50.885418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="61.663002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="67.914505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,181.4,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,192.27,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="14.228414" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="25.018503" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="31.270002" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,229.79,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 2</tspan> </text> <text transform="matrix(1,0,0,-1,240.66,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="11.452748" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="16.666498" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="22.917999" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="29.169498" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="35.420998" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="52.087498" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="58.338997" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,305.26,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,316.13,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="-189.17" y="24.620001"> 3</tspan> <tspan style="font-size: 12.50px; " x="-180.14284" y="24.620001"> ×</tspan> <tspan style="font-size: 12.50px; " x="-169.36525" y="24.620001"> 1</tspan> <tspan style="font-size: 12.50px; " x="-163.11375" y="24.620001"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,159.28,41.31)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 4</tspan> </text> <text transform="matrix(1,0,0,-1,170.15,36.14)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="14.228414" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="25.006001" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="31.2575" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,207.67,41.31)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 2</tspan> </text> <text transform="matrix(1,0,0,-1,218.54,36.14)"> <tspan style="font-size: 12.50px; " x="30.219999" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="11.452748" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="17.704248" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="23.955748" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="249.33" y="-12.5"> (</tspan> <tspan style="font-size: 12.50px; " x="253.4935" y="-12.5"> 2</tspan> <tspan style="font-size: 12.50px; " x="259.745" y="-12.5"> 8</tspan> <tspan style="font-size: 12.50px; " x="265.99649" y="-12.5"> )</tspan> </text> </g> </g> </svg></span>在200天时间内,<svg height="14.875" id="M184" style="vertical-align:-3.25793pt;width:56.712502px;" version="1.1" viewbox="0 0 56.712502 14.875" width="56.712502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.875)"> <g transform="translate(72,-60.1)"> <text transform="matrix(1,0,0,-1,-71.95,63.4)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.27)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.4)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 6</tspan> </text> </g> </g> </svg>。死亡率人均率在一天<sup>1</sup>。数据<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig2/" target="_blank">2</一个>,<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig3/" target="_blank">3</一个>,<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig4/" target="_blank">4</一个>显示,图形化的数值结果。显然,颞课程的健康和被感染的肝细胞,病毒载量都几乎相同的模型。</span></p> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig2"> <div class="floats-partial-content fig-content-fig2"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.002" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.002.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图2</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig2/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.875" id="M185" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 56.712502 14.875" width="56.712502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.875)"> <g transform="translate(72,-60.1)"> <text transform="matrix(1,0,0,-1,-71.95,63.4)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.27)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.4)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 6</tspan> </text> </g> </g> </svg> <table> 比较健康的肝细胞数量:治愈的情况下()。</t一个ble> </div> </div> </div> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig3"> <div class="floats-partial-content fig-content-fig3"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.003" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.003.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图3</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig3/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.875" id="M186" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 56.712502 14.875" width="56.712502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.875)"> <g transform="translate(72,-60.1)"> <text transform="matrix(1,0,0,-1,-71.95,63.4)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.27)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.4)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 6</tspan> </text> </g> </g> </svg> <table> 比较感染肝细胞数量:治愈的情况下()。</t一个ble> </div> </div> </div> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig4"> <div class="floats-partial-content fig-content-fig4"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.004" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.004.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图4</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig4/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.875" id="M187" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 56.712502 14.875" width="56.712502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.875)"> <g transform="translate(72,-60.1)"> <text transform="matrix(1,0,0,-1,-71.95,63.4)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.27)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.4)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 6</tspan> </text> </g> </g> </svg> <table> 比较治疗时的丙肝病毒负荷发生()。</t一个ble> </div> </div> </div> <p><span class="statement" id="casee2"><span class="statement-title"><i class="statement-title">例2(地方病)。</我></span>在本例中,我们使用相同的初始条件(<一个href="#EEq5.1">26</一个>),相同的参数向量<svg height="11.7875" id="M188" style="vertical-align:-0.13794pt;width:14.6625px;" version="1.1" viewbox="0 0 14.6625 11.7875" width="14.6625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,11.7875)"> <g transform="translate(72,-62.57)"> <text transform="matrix(1,0,0,-1,-71.95,62.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.4,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> </g> </g> </svg>,但现在<svg height="13.55" id="M189" style="vertical-align:-2.29482pt;width:50.599998px;" version="1.1" viewbox="0 0 50.599998 13.55" width="50.599998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,13.55)"> <g transform="translate(72,-61.16)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="9.5772982" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="21.617687" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="27.869186" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="34.120686" y="0"> 0</tspan> </text> </g> </g> </svg>,在800天内。现在,我们有<svg height="14.75" id="M190" style="vertical-align:-3.25793pt;width:56.712502px;" version="1.1" viewbox="0 0 56.712502 14.75" width="56.712502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 2</tspan> </text> </g> </g> </svg>。结果图形如图<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig5/" target="_blank">5</一个>,<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig6/" target="_blank">6</一个>,<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig7/" target="_blank">7</一个>。可以观察到,有些小差异与获得的每三个群体的进化模型。然而,他们有相同的渐近行为。<br>恢复,这三个群体的进化分析本质上是相同的模型。因此,对于本研究的主要目的(监测肝损伤没有活检),它足以考虑限制模型只有三个人口(<一个href="#EEq4.1">5</一个>)。</span></p> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig5"> <div class="floats-partial-content fig-content-fig5"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.005" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.005.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图5</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig5/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.75" id="M191" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 56.712502 14.75" width="56.712502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 2</tspan> </text> </g> </g> </svg> <table> 比较健康的肝细胞演进:流行情况()。</t一个ble> </div> </div> </div> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig6"> <div class="floats-partial-content fig-content-fig6"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.006" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.006.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图6</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig6/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.75" id="M192" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 56.712502 14.75" width="56.712502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 2</tspan> </text> </g> </g> </svg> <table> 比较它执着肝细胞演进:流行情况()。</t一个ble> </div> </div> </div> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig7"> <div class="floats-partial-content fig-content-fig7"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.007" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.007.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图7</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig7/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.75" id="M193" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 56.712502 14.75" width="56.712502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 2</tspan> </text> </g> </g> </svg> <table> 比较丙肝病毒负荷:流行情况()。</t一个ble> </div> </div> </div> <h4 id="parameter-numerical-estimation-and-hepatic-damage-monitoring-without-liver-biopsies">6。参数数值估计和肝损伤监测没有肝脏活检</h4> <p>在以下,通过数值模拟,我们表明,可以监测肝损害没有切片,在治愈和流行情况。这一目标,它是必不可少的足够数量的病毒载量的测量,和一个合理的评价人口初始值。这些初始值可以提供,原则上,由一个专家医生。</p> <p>数值估计的参数<svg height="10.7375" id="M194" style="vertical-align:-0.13794pt;width:8.6000004px;" version="1.1" viewbox="0 0 8.6000004 10.7375" width="8.6000004" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.7375)"> <g transform="translate(72,-63.41)"> <text transform="matrix(1,0,0,-1,-71.95,63.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,<svg height="10.8375" id="M195" style="vertical-align:-3.2316pt;width:15.1375px;" version="1.1" viewbox="0 0 15.1375 10.8375" width="15.1375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.8375)"> <g transform="translate(72,-63.33)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,<svg height="9.875" id="M196" style="vertical-align:-2.29482pt;width:7.7624998px;" version="1.1" viewbox="0 0 7.7624998 9.875" width="7.7624998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,9.875)"> <g transform="translate(72,-64.1)"> <text transform="matrix(1,0,0,-1,-71.95,66.44)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,<svg height="10.9" id="M197" style="vertical-align:-3.27548pt;width:19.012501px;" version="1.1" viewbox="0 0 19.012501 10.9" width="19.012501" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.9)"> <g transform="translate(72,-63.28)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>和最初的病毒载量<svg height="14.3875" id="M198" style="vertical-align:-3.25793pt;width:15.2px;" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>,进行了使用DIFFPAR,用MATLAB数值工具(<一个href="#B7">28</一个>,<一个href="#B27">29日</一个>]。因此,阈值参数的数值评估<svg height="14.3875" id="M199" style="vertical-align:-3.25793pt;width:17.7875px;" version="1.1" viewbox="0 0 17.7875 14.3875" width="17.7875" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>直接获得。这个目的,数值生成病毒载量通过求解数值模型(<一个href="#EEq4.1">5</一个>30天内),对于一个给定的参数向量<svg height="10.7375" id="M200" style="vertical-align:-0.13794pt;width:8.3125px;" version="1.1" viewbox="0 0 8.3125 10.7375" width="8.3125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.7375)"> <g transform="translate(72,-63.41)"> <text transform="matrix(1,0,0,-1,-71.95,63.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>和初始条件。在10%的正常分布噪声模拟测量误差被添加到这些数据。接下来,提出了两种情形。<span class="list"><span class="list-item"><span class="list-label">(1)</span><span class="list-content">初始条件是清楚的所有变量。</span></span><span class="list-item"><span class="list-label">(2)</span><span class="list-content">准确的初始值是已知的唯一<svg height="14.9375" id="M201" style="vertical-align:-3.25793pt;width:75.324997px;" version="1.1" viewbox="0 0 75.324997 14.9375" width="75.324997" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.9375)"> <g transform="translate(72,-60.05)"> <text transform="matrix(1,0,0,-1,-71.95,63.35)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.22)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-48.84,63.35)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.040389" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="18.291889" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="24.543388" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="30.794889" y="0"> 0</tspan> </text> </g> </g> </svg>,<svg height="14.9375" id="M202" style="vertical-align:-3.25793pt;width:67.5625px;" version="1.1" viewbox="0 0 67.5625 14.9375" width="67.5625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.9375)"> <g transform="translate(72,-60.05)"> <text transform="matrix(1,0,0,-1,-71.95,63.35)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.22)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-48.79,63.35)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="24.530886" y="0"> 0</tspan> </text> </g> </g> </svg>。在这种情况下,10%的正常分布噪声添加到初始载荷<svg height="14.3875" id="M203" style="vertical-align:-3.25793pt;width:15.2px;" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>。然后估计参数和最初的病毒载量。</span></span></span></p> <p>参数估计和初始条件确定应用经典最小二乘准则,或因此,关于最小化<svg height="10.7375" id="M204" style="vertical-align:-0.13794pt;width:8.3125px;" version="1.1" viewbox="0 0 8.3125 10.7375" width="8.3125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.7375)"> <g transform="translate(72,-63.41)"> <text transform="matrix(1,0,0,-1,-71.95,63.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>和<svg height="9.875" id="M205" style="vertical-align:-2.29482pt;width:7.9375px;" version="1.1" viewbox="0 0 7.9375 9.875" width="7.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,9.875)"> <g transform="translate(72,-64.1)"> <text transform="matrix(1,0,0,-1,-71.95,66.44)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>目标函数<span class="equation" id="eq18"> <svg height="48.387501" id="M206" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 48.387501" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,48.3875)"> <g transform="translate(72,-33.29)"> <text transform="matrix(1,0,0,-1,107.87,49.67)"> <tspan style="font-size: 12.50px; " x="51.779999" y="-7.2600002"> 1</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="8.7270937" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="12.890593" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="19.442165" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="24.655916" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="30.907415" y="0"> )</tspan> <tspan style="font-size: 12.50px; " x="38.534245" y="0"> =</tspan> </text> <g> <path d="m 159.65,52.8 6.25,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,159.65,40.92)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 2</tspan> </text> <text transform="matrix(1,0,0,-1,172.06,65.61)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,167.09,43.12)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> </text> <text transform="matrix(1,0,0,-1,168.63,35.94)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 8.75px; " x="2.7218721" y="0"> =</tspan> <tspan style="font-size: 8.75px; " x="8.7169924" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,183.25,49.67)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,192.94,46.55)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,196.16,47.16)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="5.8499999" y="-2.51"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,209.2,46.55)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,215.2,49.67)"> <tspan style="font-size: 12.50px; " x="23.43" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="29.280001" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 12.50px; " x="11.340221" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,248.39,46.55)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,251.61,49.67)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ;</tspan> <tspan style="font-size: 12.50px; " x="5.551332" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,261.09,46.55)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,265.96,49.67)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="11.452748" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="16.666498" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="23.219999" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="29.071404" y="2.51"> 吗?</tspan> </text> <text transform="matrix(1,0,0,-1,300.89,57.21)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 2</tspan> </text> <text transform="matrix(1,0,0,-1,305.76,49.67)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="162.11" y="0.15000001"> (</tspan> <tspan style="font-size: 12.50px; " x="166.2735" y="0.15000001"> 2</tspan> <tspan style="font-size: 12.50px; " x="172.52499" y="0.15000001"> 9</tspan> <tspan style="font-size: 12.50px; " x="178.7765" y="0.15000001"> )</tspan> </text> </g> </g> </svg></span>在哪里<svg height="14.3875" id="M207" style="vertical-align:-3.25793pt;width:42.412498px;" version="1.1" viewbox="0 0 42.412498 14.3875" width="42.412498" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="9.7148314" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="21.75522" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-43,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>,<svg height="14.775" id="M208" style="vertical-align:-3.27548pt;width:107.6625px;" version="1.1" viewbox="0 0 107.6625 14.775" width="107.6625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.775)"> <g transform="translate(72,-60.18)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="10.014903" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="22.055292" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="26.21879" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="32.995419" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="38.209167" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-26.12,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-21.73,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="11.315215" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="16.528967" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,2.42,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,9.92,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> )</tspan> </text> </g> </g> </svg>,<svg height="14.75" id="M209" style="vertical-align:-3.25793pt;width:71.375px;" version="1.1" viewbox="0 0 71.375 14.75" width="71.375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="7.1892252" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="11.352724" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="15.266163" y="0"> ;</tspan> <tspan style="font-size: 12.50px; " x="20.817495" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-47.21,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-42.34,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="11.452748" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="16.666498" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="23.218071" y="0"> )</tspan> </text> </g> </g> </svg>病毒载量的解决方案减少模型(<一个href="#EEq4.1">5</一个>)。权重<svg height="11.3375" id="M210" style="vertical-align:-3.2316pt;width:16.262501px;" version="1.1" viewbox="0 0 16.262501 11.3375" width="16.262501" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,11.3375)"> <g transform="translate(72,-62.93)"> <text transform="matrix(1,0,0,-1,-71.95,66.2)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.26,63.07)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>计算按照下列规则:<span class="equation" id="eq19"> <svg height="58.662498" id="M211" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 58.662498" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,58.6625)"> <g transform="translate(72,-25.07)"> <text transform="matrix(1,0,0,-1,143.93,45.41)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,153.62,42.29)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,160.31,45.41)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.04" y="-12.07"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="12.04" y="-6.9400001"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="12.04" y="3.1900001"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="12.04" y="13.31"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="12.04" y="18.379999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="25.549999" y="-18.09"> 1</tspan> </text> <g> <path d="m 181.55,59.37 14.87,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,181.55,45.68)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,191.55,50.57)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 2</tspan> <tspan style="font-size: 8.75px; " x="-2.8199999" y="8.6899996"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,197.62,56.25)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="15.616247" y="0"> 我</tspan> <tspan style="font-size: 12.50px; " x="19.092081" y="0"> f</tspan> <tspan style="font-size: 12.50px; " x="27.431581" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,232.24,53.12)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,238.94,56.25)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ></tspan> <tspan style="font-size: 12.50px; " x="12.03" y="0.83999997"> v</tspan> </text> <g> <path d="m 262.58,67.16 5.92,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,262.58,56.25)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="5.9264221" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="-82.230003" y="26.620001"> 0</tspan> <tspan style="font-size: 12.50px; " x="-75.9785" y="26.620001"> ,</tspan> <tspan style="font-size: 12.50px; " x="-49.334606" y="26.620001"> 我</tspan> <tspan style="font-size: 12.50px; " x="-45.858772" y="26.620001"> f</tspan> <tspan style="font-size: 12.50px; " x="-37.531776" y="26.620001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,232.24,26.5)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,238.94,29.63)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.03" y="0.83999997"> v</tspan> </text> <g> <path d="m 262.58,40.54 5.92,0" style="fill:none;stroke:#000000;stroke-width:0.82499999;stroke-linecap:butt;stroke-linejoin:miter;stroke-miterlimit:10;stroke-opacity:1;stroke-dasharray:none"></path> </g> <text transform="matrix(1,0,0,-1,262.58,29.63)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 12.50px; " x="5.9264221" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="205.28999" y="-15.78"> (</tspan> <tspan style="font-size: 12.50px; " x="209.45351" y="-15.78"> 3</tspan> <tspan style="font-size: 12.50px; " x="215.705" y="-15.78"> 0</tspan> <tspan style="font-size: 12.50px; " x="221.9565" y="-15.78"> )</tspan> </text> </g> </g> </svg></span>在哪里<svg height="7.1624999" id="M212" style="vertical-align:-0.11285pt;width:7.5374999px;" version="1.1" viewbox="0 0 7.5374999 7.1624999" width="7.5374999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,7.1625)"> <g transform="translate(72,-66.27)"> <text transform="matrix(1,0,0,-1,-71.95,66.44)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>舍入单位在IEEE标准双精度浮点运算。</p> <h5 id="sec6.1">6.1。治愈的情况下</h5> <p>数据生成使用参数<span class="equation" id="EEq6.1"> <svg height="50.25" id="M213" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 50.25" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,50.25)"> <g transform="translate(72,-31.8)"> <text transform="matrix(1,0,0,-1,97.32,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,103.87,66.2)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,112.42,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="14.12" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="19.98" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,139.37,66.2)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="0" y="8.1899996"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,144.45,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,156.43,66.2)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,161.51,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,174.33,66.14)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="0" y="8.1300001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,179.41,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,192.23,66.14)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="0" y="8.1300001"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,197.31,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,208.63,66.14)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> <text transform="matrix(1,0,0,-1,213.71,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,226.53,66.14)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> <tspan style="font-size: 8.75px; " x="0" y="9.0200005"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,234.03,58.62)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="-121.61" y="22.209999"> =</tspan> <tspan style="font-size: 12.50px; " x="-109.57" y="24.719999"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="-103.72" y="22.209999"> 1</tspan> <tspan style="font-size: 12.50px; " x="-97.468498" y="22.209999"> 0</tspan> <tspan style="font-size: 12.50px; " x="-91.217003" y="22.209999"> 0</tspan> <tspan style="font-size: 12.50px; " x="-84.9655" y="22.209999"> ,</tspan> <tspan style="font-size: 12.50px; " x="-75.588249" y="22.209999"> 3</tspan> <tspan style="font-size: 12.50px; " x="-66.561081" y="22.209999"> ×</tspan> <tspan style="font-size: 12.50px; " x="-55.783497" y="22.209999"> 1</tspan> <tspan style="font-size: 12.50px; " x="-49.531998" y="22.209999"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,190.76,41.58)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,201.63,36.41)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="9.364747" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="18.391912" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="29.182001" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="35.433502" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,243.32,41.58)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 2</tspan> </text> <text transform="matrix(1,0,0,-1,254.19,36.41)"> <tspan style="font-size: 12.50px; " x="59.389999" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="9.364747" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="15.616247" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="24.993498" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="31.244997" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="37.496498" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="43.747997" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="53.125248" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="213.67999" y="-12.36"> (</tspan> <tspan style="font-size: 12.50px; " x="217.84351" y="-12.36"> 3</tspan> <tspan style="font-size: 12.50px; " x="224.095" y="-12.36"> 1</tspan> <tspan style="font-size: 12.50px; " x="230.3465" y="-12.36"> )</tspan> </text> </g> </g> </svg></span>和初始条件<span class="equation" id="EEq6.2"> <svg height="46.1875" id="M214" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 46.1875" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,46.1875)"> <g transform="translate(72,-35.05)"> <text transform="matrix(1,0,0,-1,147.68,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,153.88,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,162.23,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="14.12" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="19.969999" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,193.12,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,201.84,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2012482" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,217.97,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,226.73,61.13)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="5.2137508" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,239.13,58.01)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,244.01,58.62)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="-81.779999" y="19.77"> =</tspan> <tspan style="font-size: 12.50px; " x="-69.752113" y="19.77"> (</tspan> <tspan style="font-size: 12.50px; " x="-65.588615" y="19.77"> 4</tspan> <tspan style="font-size: 12.50px; " x="-59.337116" y="19.77"> 5</tspan> <tspan style="font-size: 12.50px; " x="-53.085613" y="19.77"> 0</tspan> <tspan style="font-size: 12.50px; " x="-46.834114" y="19.77"> 0</tspan> <tspan style="font-size: 12.50px; " x="-40.582615" y="19.77"> ,</tspan> <tspan style="font-size: 12.50px; " x="-31.205364" y="19.77"> 5</tspan> <tspan style="font-size: 12.50px; " x="-24.953865" y="19.77"> 0</tspan> <tspan style="font-size: 12.50px; " x="-18.702366" y="19.77"> 0</tspan> <tspan style="font-size: 12.50px; " x="-12.450865" y="19.77"> ,</tspan> <tspan style="font-size: 12.50px; " x="-3.0736151" y="19.77"> 4</tspan> <tspan style="font-size: 12.50px; " x="3.1778851" y="19.77"> 0</tspan> <tspan style="font-size: 12.50px; " x="9.4293852" y="19.77"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.680885" y="19.77"> )</tspan> <tspan style="font-size: 12.50px; " x="21.932384" y="19.77"> 。</tspan> <tspan style="font-size: 12.50px; " x="223.86" y="8.2200003"> (</tspan> <tspan style="font-size: 12.50px; " x="228.0235" y="8.2200003"> 3</tspan> <tspan style="font-size: 12.50px; " x="234.27499" y="8.2200003"> 2</tspan> <tspan style="font-size: 12.50px; " x="240.5265" y="8.2200003"> )</tspan> </text> </g> </g> </svg></span></p> <p>在这种情况下,<svg height="14.875" id="M215" style="vertical-align:-3.25793pt;width:56.712502px;" version="1.1" viewbox="0 0 56.712502 14.875" width="56.712502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.875)"> <g transform="translate(72,-60.1)"> <text transform="matrix(1,0,0,-1,-71.95,63.4)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.27)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.4)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 6</tspan> </text> </g> </g> </svg>。生成的数据是使用最初的病毒载量<svg height="14.3875" id="M216" style="vertical-align:-3.25793pt;width:15.2px;" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>有和没有噪声(见表<一个href="//www.newsama.com/journals/cmmm/2011/325470/tab1/" target="_blank">1</一个>)。</p> <div class="floats-partial-section partial-other-wrapper" data-section="tab1"> <div class="floats-partial-content fig-content-tab1"> <table class="table-group" id="tab1"> <tbody> <tr> <td> <table class="table"> <tbody> <tr> <td class="thead-hr" colspan="3"> <hr></td> </tr> <tr> <td align="left"></td> <td align="center">病毒载量(<svg height="10.575" id="M218" style="vertical-align:-0.20064pt" version="1.1" viewbox="0 0 12.625 10.575" width="12.625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.575)"> <g transform="translate(72,-63.54)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> </g> </g> </svg>)</td><td一个l我gn="center">病毒载量(<svg height="10.575" id="M219" style="vertical-align:-0.20064pt" version="1.1" viewbox="0 0 12.625 10.575" width="12.625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.575)"> <g transform="translate(72,-63.54)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> </g> </g> </svg>)</td></tr> <tr> <td align="left"><span style="width: 53.487499px;"> <svg height="13.5625" id="M220" style="vertical-align:-2.21957pt" version="1.1" viewbox="0 0 53.487499 13.5625" width="53.487499" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,13.5625)"> <g transform="translate(72,-61.15)"> <text transform="matrix(1,0,0,-1,-71.95,63.41)"> <tspan style="font-size: 12.50px; " x="0" y="0"> T</tspan> <tspan style="font-size: 12.50px; " x="7.5268059" y="0"> 我</tspan> <tspan style="font-size: 12.50px; " x="11.00264" y="0"> 米</tspan> <tspan style="font-size: 12.50px; " x="20.729975" y="0"> e</tspan> <tspan style="font-size: 12.50px; " x="30.444805" y="0"> (</tspan> <tspan style="font-size: 12.50px; " x="34.608303" y="0"> </tspan> <tspan style="font-size: 12.50px; " x="38.521744" y="0"> )</tspan> </text> </g> </g> </svg></span></td> <td align="center">(UI /<我>μ</我>L)</td><td一个l我gn="center">(UI /<我>μ</我>L)</td></tr> <tr> <td align="left"></td> <td align="center">(<svg height="14.3875" id="M221" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>没有噪音)</td><td一个l我gn="center">(<svg height="14.3875" id="M222" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>与噪音)</td></tr> <tr> <td align="center" colspan="3"> <hr></td> </tr> <tr> <td align="left">0小时</td><td一个l我gn="center">400年</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M223" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 2</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">2小时</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M224" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M225" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">4个小时</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M226" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M227" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">8小时</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M228" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M229" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">16个小时</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M230" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M231" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">24小时</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M232" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M233" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">2天</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M234" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 2</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M235" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 2</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">3天</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M236" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M237" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">4天</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M238" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M239" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">6天</td><td一个l我gn="center"><span style="width: 112.7125px;"> <svg height="14.375" id="M240" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.375" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 1</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 112.7125px;"> <svg height="14.375" id="M241" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.375" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 1</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">8天</td><td一个l我gn="center"><span style="width: 112.7125px;"> <svg height="14.375" id="M242" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.375" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 2</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 112.7125px;"> <svg height="14.375" id="M243" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.375" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 2</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">10天</td><td一个l我gn="center"><span style="width: 112.7125px;"> <svg height="14.375" id="M244" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.375" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 112.7125px;"> <svg height="14.375" id="M245" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.375" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">14天</td><td一个l我gn="center"><span style="width: 112.7125px;"> <svg height="14.4625" id="M246" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.4625" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.4625)"> <g transform="translate(72,-60.43)"> <text transform="matrix(1,0,0,-1,-71.95,60.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,65.96)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 6</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 112.7125px;"> <svg height="14.4625" id="M247" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.4625" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.4625)"> <g transform="translate(72,-60.43)"> <text transform="matrix(1,0,0,-1,-71.95,60.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,65.96)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 6</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">18天</td><td一个l我gn="center"><span style="width: 112.7125px;"> <svg height="14.4625" id="M248" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.4625" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.4625)"> <g transform="translate(72,-60.43)"> <text transform="matrix(1,0,0,-1,-71.95,60.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,65.96)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 6</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 112.7125px;"> <svg height="14.4625" id="M249" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.4625" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.4625)"> <g transform="translate(72,-60.43)"> <text transform="matrix(1,0,0,-1,-71.95,60.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,65.96)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 6</tspan> </text> </g> </g> </svg></span></td> </tr> <tr class="table-tr"> <td colspan="3"> <hr class="tbody-hr"></td> </tr> </tbody> </table></td> </tr> </tbody> </table> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">表1</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/tab1/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> 治愈的情况下生成的数据(<svg height="14.875" id="M217" style="vertical-align:-3.25793pt;width:56.712502px;" version="1.1" viewbox="0 0 56.712502 14.875" width="56.712502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.875)"> <g transform="translate(72,-60.1)"> <text transform="matrix(1,0,0,-1,-71.95,63.4)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.27)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.4)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 6</tspan> </text> </g> </g> </svg>)。</d我v></d我v></d我v><p>只使用病毒载量数据(<svg height="10.575" id="M250" style="vertical-align:-0.20064pt;width:12.625px;" version="1.1" viewbox="0 0 12.625 10.575" width="12.625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.575)"> <g transform="translate(72,-63.54)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>),第二列在表<一个href="//www.newsama.com/journals/cmmm/2011/325470/tab1/" target="_blank">1</一个>和初始条件(<一个href="#EEq6.2">32</一个>),我们估计参数<svg height="10.7375" id="M251" style="vertical-align:-0.13794pt;width:8.6000004px;" version="1.1" viewbox="0 0 8.6000004 10.7375" width="8.6000004" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.7375)"> <g transform="translate(72,-63.41)"> <text transform="matrix(1,0,0,-1,-71.95,63.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,<svg height="10.8375" id="M252" style="vertical-align:-3.2316pt;width:15.1375px;" version="1.1" viewbox="0 0 15.1375 10.8375" width="15.1375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.8375)"> <g transform="translate(72,-63.33)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,<svg height="9.875" id="M253" style="vertical-align:-2.29482pt;width:7.7624998px;" version="1.1" viewbox="0 0 7.7624998 9.875" width="7.7624998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,9.875)"> <g transform="translate(72,-64.1)"> <text transform="matrix(1,0,0,-1,-71.95,66.44)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,<svg height="10.9" id="M254" style="vertical-align:-3.27548pt;width:19.012501px;" version="1.1" viewbox="0 0 19.012501 10.9" width="19.012501" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.9)"> <g transform="translate(72,-63.28)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>。优化过程参数的初始值开始<span class="equation" id="eq20"> <svg height="19.8125" id="M255" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 19.8125" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,19.8125)"> <g transform="translate(72,-56.15)"> <text transform="matrix(1,0,0,-1,94.82,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,101.37,57.63)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,109.72,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.04" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="17.889999" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="24.1415" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="30.393" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="36.644501" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="46.009247" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="55.036411" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="65.8265" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.078003" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,188.05,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,198.92,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="18.404415" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="29.182001" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="35.433502" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,240.61,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 2</tspan> </text> <text transform="matrix(1,0,0,-1,251.48,60.76)"> <tspan style="font-size: 12.50px; " x="59.389999" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="67.330002" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="25.006001" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="31.2575" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="37.508999" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="53.137749" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="216.39" y="-0.19"> (</tspan> <tspan style="font-size: 12.50px; " x="220.5535" y="-0.19"> 3</tspan> <tspan style="font-size: 12.50px; " x="226.80499" y="-0.19"> 3</tspan> <tspan style="font-size: 12.50px; " x="233.0565" y="-0.19"> )</tspan> </text> </g> </g> </svg></span></p> <p>表<一个href="//www.newsama.com/journals/cmmm/2011/325470/tab2/" target="_blank">2</一个>使用DIFFPAR两次显示了结果。数量的时间课程数据所示<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig8/" target="_blank">8</一个>,<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig9/" target="_blank">9</一个>,<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig10/" target="_blank">10</一个>。观察到的数据<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig9/" target="_blank">9</一个>和<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig10/" target="_blank">10</一个>估计理论和曲线是几乎一样的。</p> <div class="floats-partial-section partial-other-wrapper" data-section="tab2"> <div class="floats-partial-content fig-content-tab2"> <table class="table-group" id="tab2"> <tbody> <tr> <td> <table class="table"> <tbody> <tr> <td class="thead-hr" colspan="6"> <hr></td> </tr> <tr class="thead"> <td align="left"></td> <td align="center"><span style="width: 8.6000004px;"> <svg height="10.7375" id="M260" style="vertical-align:-0.13794pt" version="1.1" viewbox="0 0 8.6000004 10.7375" width="8.6000004" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.7375)"> <g transform="translate(72,-63.41)"> <text transform="matrix(1,0,0,-1,-71.95,63.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 15.1375px;"> <svg height="10.8375" id="M261" style="vertical-align:-3.2316pt" version="1.1" viewbox="0 0 15.1375 10.8375" width="15.1375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.8375)"> <g transform="translate(72,-63.33)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 7.7624998px;"> <svg height="9.875" id="M262" style="vertical-align:-2.29482pt" version="1.1" viewbox="0 0 7.7624998 9.875" width="7.7624998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,9.875)"> <g transform="translate(72,-64.1)"> <text transform="matrix(1,0,0,-1,-71.95,66.44)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 19.012501px;"> <svg height="10.9" id="M263" style="vertical-align:-3.27548pt" version="1.1" viewbox="0 0 19.012501 10.9" width="19.012501" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.9)"> <g transform="translate(72,-63.28)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 17.7875px;"> <svg height="14.3875" id="M264" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 17.7875 14.3875" width="17.7875" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td class="thead-hr" colspan="6"> <hr></td> </tr> <tr> <td align="left"> <svg height="11.7875" id="M265" style="vertical-align:-0.13794pt" version="1.1" viewbox="0 0 14.6625 11.7875" width="14.6625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,11.7875)"> <g transform="translate(72,-62.57)"> <text transform="matrix(1,0,0,-1,-71.95,62.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-65.4,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ∗</tspan> </text> </g> </g> </svg>确切的</td><td一个l我gn="center"><span style="width: 54.099998px;"> <svg height="14.5" id="M266" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 54.099998 14.5" width="54.099998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.5)"> <g transform="translate(72,-60.4)"> <text transform="matrix(1,0,0,-1,-71.95,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="9.0271664" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="19.804752" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="26.056252" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-39.64,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> </g> </g> </svg></span></td> <td align="center">5</td><td一个l我gn="center">One hundred.</td><td一个l我gn="center">5</td><td一个l我gn="center">0.6</td></tr> <tr> <td align="left"> <svg height="14.2375" id="M267" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 8.3125 14.2375" width="8.3125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.2375)"> <g transform="translate(72,-60.61)"> <text transform="matrix(1,0,0,-1,-65.8,63.52)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ̂</tspan> <tspan style="font-size: 12.50px; " x="-6.1500001" y="2.72"> </tspan> </text> </g> </g> </svg>估计</td><td一个l我gn="center"><span style="width: 89.262497px;"> <svg height="14.5" id="M268" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 89.262497 14.5" width="89.262497" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.5)"> <g transform="translate(72,-60.4)"> <text transform="matrix(1,0,0,-1,-71.95,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="37.158916" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="47.936501" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="54.188004" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-11.5,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> </g> </g> </svg></span></td> <td align="center">6.3993</td><td一个l我gn="center">123.91</td><td一个l我gn="center">6.4062</td><td一个l我gn="center">0.78</td></tr> <tr> <td align="left">错误</td><td一个l我gn="center">71.18%</td><td一个l我gn="center">27.99%</td><td一个l我gn="center">23.91%</td><td一个l我gn="center">28.12%</td><td一个l我gn="center">30.00%</td></tr> <tr class="table-tr"> <td colspan="6"> <hr class="tbody-hr"></td> </tr> </tbody> </table></td> </tr> </tbody> </table> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">表2</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/tab2/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> 结果当<svg height="14.3875" id="M256" style="vertical-align:-3.25793pt;width:24.674999px;" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg>,<svg height="14.3875" id="M257" style="vertical-align:-3.25793pt;width:24.725px;" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg>,<svg height="14.3875" id="M258" style="vertical-align:-3.25793pt;width:15.2px;" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>是已知的(<svg height="14.875" id="M259" style="vertical-align:-3.25793pt;width:56.712502px;" version="1.1" viewbox="0 0 56.712502 14.875" width="56.712502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.875)"> <g transform="translate(72,-60.1)"> <text transform="matrix(1,0,0,-1,-71.95,63.4)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.27)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.4)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 6</tspan> </text> </g> </g> </svg>)。</d我v></d我v></d我v><d我v class="floats-partial-section partial-carousel-wrapper" data-section="fig8"> <div class="floats-partial-content fig-content-fig8"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.008" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.008.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图8</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig8/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.3875" id="M269" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M270" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M271" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg> <table> 治愈的例子:比较健康肝细胞的数量,,,给出了。</t一个ble> </div> </div> </div> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig9"> <div class="floats-partial-content fig-content-fig9"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.009" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.009.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图9</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig9/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.3875" id="M272" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M273" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M274" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg> <table> 治愈的例子:比较受感染的肝细胞的数量(肝损伤),,,给出了。</t一个ble> </div> </div> </div> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig10"> <div class="floats-partial-content fig-content-fig10"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.0010" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.0010.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图10</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig10/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.3875" id="M275" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M276" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M277" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg> <table> 治愈的例子:比较病毒载量,,,给出了。</t一个ble> </div> </div> </div> <p>每个参数表的95%置信区间<一个href="//www.newsama.com/journals/cmmm/2011/325470/tab2/" target="_blank">2</一个>按照给出的不平等(估计参数出现在中间):<span class="equation" id="eq21"> <svg height="95.574997" id="M278" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 95.574997" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,95.575)"> <g transform="translate(72,4.46)"> <text transform="matrix(1,0,0,-1,84.33,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="37.158916" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="47.936501" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="54.188004" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,144.78,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,159.12,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="27.656635" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="33.908134" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="40.159637" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="49.186802" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="59.976891" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="66.228394" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,231.6,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,245.94,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.040389" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="18.291889" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.417639" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="27.66914" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="33.920639" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="40.172138" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="49.199306" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="59.976891" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="66.228394" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,318.43,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,329.3,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="-208.03999" y="20.469999"> 6</tspan> <tspan style="font-size: 12.50px; " x="-201.7885" y="20.469999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-198.66275" y="20.469999"> 3</tspan> <tspan style="font-size: 12.50px; " x="-192.41125" y="20.469999"> 9</tspan> <tspan style="font-size: 12.50px; " x="-186.15974" y="20.469999"> 3</tspan> <tspan style="font-size: 12.50px; " x="-179.90825" y="20.469999"> 3</tspan> <tspan style="font-size: 12.50px; " x="-170.19342" y="20.469999"> =</tspan> <tspan style="font-size: 12.50px; " x="-158.15303" y="20.469999"> 6</tspan> <tspan style="font-size: 12.50px; " x="-151.90154" y="20.469999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-148.77579" y="20.469999"> 3</tspan> <tspan style="font-size: 12.50px; " x="-142.52428" y="20.469999"> 9</tspan> <tspan style="font-size: 12.50px; " x="-136.27278" y="20.469999"> 9</tspan> <tspan style="font-size: 12.50px; " x="-130.02129" y="20.469999"> 3</tspan> <tspan style="font-size: 12.50px; " x="-120.29395" y="20.469999"> =</tspan> <tspan style="font-size: 12.50px; " x="-108.25356" y="20.469999"> 6</tspan> <tspan style="font-size: 12.50px; " x="-102.00206" y="20.469999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-98.876305" y="20.469999"> 4</tspan> <tspan style="font-size: 12.50px; " x="-92.624809" y="20.469999"> 0</tspan> <tspan style="font-size: 12.50px; " x="-86.373306" y="20.469999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-80.121803" y="20.469999"> 3</tspan> <tspan style="font-size: 12.50px; " x="-73.870308" y="20.469999"> ,</tspan> <tspan style="font-size: 12.50px; " x="-208.03999" y="40.950001"> 1</tspan> <tspan style="font-size: 12.50px; " x="-201.7885" y="40.950001"> 2</tspan> <tspan style="font-size: 12.50px; " x="-195.537" y="40.950001"> 3</tspan> <tspan style="font-size: 12.50px; " x="-189.28551" y="40.950001"> 。</tspan> <tspan style="font-size: 12.50px; " x="-186.15974" y="40.950001"> 9</tspan> <tspan style="font-size: 12.50px; " x="-179.90825" y="40.950001"> 0</tspan> <tspan style="font-size: 12.50px; " x="-170.19342" y="40.950001"> =</tspan> <tspan style="font-size: 12.50px; " x="-158.15303" y="40.950001"> 1</tspan> <tspan style="font-size: 12.50px; " x="-151.90154" y="40.950001"> 2</tspan> <tspan style="font-size: 12.50px; " x="-145.65002" y="40.950001"> 3</tspan> <tspan style="font-size: 12.50px; " x="-139.39853" y="40.950001"> 。</tspan> <tspan style="font-size: 12.50px; " x="-136.27278" y="40.950001"> 9</tspan> <tspan style="font-size: 12.50px; " x="-130.02129" y="40.950001"> 1</tspan> <tspan style="font-size: 12.50px; " x="-120.29395" y="40.950001"> =</tspan> <tspan style="font-size: 12.50px; " x="-108.25356" y="40.950001"> 1</tspan> <tspan style="font-size: 12.50px; " x="-102.00206" y="40.950001"> 2</tspan> <tspan style="font-size: 12.50px; " x="-95.750557" y="40.950001"> 3</tspan> <tspan style="font-size: 12.50px; " x="-89.499054" y="40.950001"> 。</tspan> <tspan style="font-size: 12.50px; " x="-86.373306" y="40.950001"> 9</tspan> <tspan style="font-size: 12.50px; " x="-80.121803" y="40.950001"> 3</tspan> <tspan style="font-size: 12.50px; " x="-73.870308" y="40.950001"> ,</tspan> <tspan style="font-size: 12.50px; " x="-208.03999" y="61.419998"> 6</tspan> <tspan style="font-size: 12.50px; " x="-201.7885" y="61.419998"> 。</tspan> <tspan style="font-size: 12.50px; " x="-198.66275" y="61.419998"> 3</tspan> <tspan style="font-size: 12.50px; " x="-192.41125" y="61.419998"> 9</tspan> <tspan style="font-size: 12.50px; " x="-186.15974" y="61.419998"> 9</tspan> <tspan style="font-size: 12.50px; " x="-179.90825" y="61.419998"> 9</tspan> <tspan style="font-size: 12.50px; " x="-170.19342" y="61.419998"> =</tspan> <tspan style="font-size: 12.50px; " x="-158.15303" y="61.419998"> 6</tspan> <tspan style="font-size: 12.50px; " x="-151.90154" y="61.419998"> 。</tspan> <tspan style="font-size: 12.50px; " x="-148.77579" y="61.419998"> 4</tspan> <tspan style="font-size: 12.50px; " x="-142.52428" y="61.419998"> 0</tspan> <tspan style="font-size: 12.50px; " x="-136.27278" y="61.419998"> 6</tspan> <tspan style="font-size: 12.50px; " x="-130.02129" y="61.419998"> 2</tspan> <tspan style="font-size: 12.50px; " x="-120.29395" y="61.419998"> =</tspan> <tspan style="font-size: 12.50px; " x="-108.25356" y="61.419998"> 6</tspan> <tspan style="font-size: 12.50px; " x="-102.00206" y="61.419998"> 。</tspan> <tspan style="font-size: 12.50px; " x="-98.876305" y="61.419998"> 4</tspan> <tspan style="font-size: 12.50px; " x="-92.624809" y="61.419998"> 1</tspan> <tspan style="font-size: 12.50px; " x="-86.373306" y="61.419998"> 2</tspan> <tspan style="font-size: 12.50px; " x="-80.121803" y="61.419998"> 5</tspan> <tspan style="font-size: 12.50px; " x="-73.870308" y="61.419998"> 。</tspan> <tspan style="font-size: 12.50px; " x="138.57001" y="30.120001"> (</tspan> <tspan style="font-size: 12.50px; " x="142.73351" y="30.120001"> 3</tspan> <tspan style="font-size: 12.50px; " x="148.985" y="30.120001"> 4</tspan> <tspan style="font-size: 12.50px; " x="155.2365" y="30.120001"> )</tspan> </text> </g> </g> </svg></span></p> <p>在一个类似的方式,只使用病毒载量表中的数据<一个href="//www.newsama.com/journals/cmmm/2011/325470/tab1/" target="_blank">1</一个>,估计<svg height="10.7375" id="M279" style="vertical-align:-0.13794pt;width:8.6000004px;" version="1.1" viewbox="0 0 8.6000004 10.7375" width="8.6000004" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.7375)"> <g transform="translate(72,-63.41)"> <text transform="matrix(1,0,0,-1,-71.95,63.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,<svg height="10.8375" id="M280" style="vertical-align:-3.2316pt;width:15.1375px;" version="1.1" viewbox="0 0 15.1375 10.8375" width="15.1375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.8375)"> <g transform="translate(72,-63.33)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,<svg height="9.875" id="M281" style="vertical-align:-2.29482pt;width:7.7624998px;" version="1.1" viewbox="0 0 7.7624998 9.875" width="7.7624998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,9.875)"> <g transform="translate(72,-64.1)"> <text transform="matrix(1,0,0,-1,-71.95,66.44)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,<svg height="10.9" id="M282" style="vertical-align:-3.27548pt;width:19.012501px;" version="1.1" viewbox="0 0 19.012501 10.9" width="19.012501" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.9)"> <g transform="translate(72,-63.28)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,最初的病毒载量<svg height="14.3875" id="M283" style="vertical-align:-3.25793pt;width:15.2px;" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>,初始值为优化过程<svg height="14.75" id="M284" style="vertical-align:-3.25793pt;width:58.037498px;" version="1.1" viewbox="0 0 58.037498 14.75" width="58.037498" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-56.41,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="24.530886" y="0"> 0</tspan> </text> </g> </g> </svg>,<span class="equation" id="eq22"> <svg height="19.8125" id="M285" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 19.8125" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,19.8125)"> <g transform="translate(72,-56.15)"> <text transform="matrix(1,0,0,-1,94.82,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,101.37,57.63)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,109.72,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.04" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="17.889999" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="24.1415" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="30.393" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="36.644501" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="46.009247" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="55.036411" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="65.8265" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.078003" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,188.05,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,198.92,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="18.404415" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="29.182001" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="35.433502" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,240.61,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 2</tspan> </text> <text transform="matrix(1,0,0,-1,251.48,60.76)"> <tspan style="font-size: 12.50px; " x="59.389999" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="67.330002" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="25.006001" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="31.2575" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="37.508999" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="53.137749" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="216.39" y="-0.19"> (</tspan> <tspan style="font-size: 12.50px; " x="220.5535" y="-0.19"> 3</tspan> <tspan style="font-size: 12.50px; " x="226.80499" y="-0.19"> 5</tspan> <tspan style="font-size: 12.50px; " x="233.0565" y="-0.19"> )</tspan> </text> </g> </g> </svg></span></p> <p>这项研究的结果发表在表<一个href="//www.newsama.com/journals/cmmm/2011/325470/tab3/" target="_blank">3</一个>。健康和被感染的肝细胞数量和病毒载量的演进图所示<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig11/" target="_blank">11</一个>,<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig12/" target="_blank">12</一个>,<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig13/" target="_blank">13</一个>。估计的参数及其95%置信区间<span class="equation" id="eq23"> <svg height="121.1625" id="M286" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 121.1625" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,121.1625)"> <g transform="translate(72,24.93)"> <text transform="matrix(1,0,0,-1,84.33,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="37.158916" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="47.936501" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="54.188004" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,144.78,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,159.12,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="27.656635" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="33.908134" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="40.159637" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="49.186802" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="59.976891" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="66.228394" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,231.6,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,245.94,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.040389" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="18.291889" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.417639" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="27.66914" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="33.920639" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="40.172138" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="49.199306" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="59.976891" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="66.228394" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,318.43,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,329.3,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="-208.03999" y="20.469999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-201.7885" y="20.469999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-198.66275" y="20.469999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-192.41125" y="20.469999"> 9</tspan> <tspan style="font-size: 12.50px; " x="-186.15974" y="20.469999"> 6</tspan> <tspan style="font-size: 12.50px; " x="-179.90825" y="20.469999"> 1</tspan> <tspan style="font-size: 12.50px; " x="-170.19342" y="20.469999"> =</tspan> <tspan style="font-size: 12.50px; " x="-158.15303" y="20.469999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-151.90154" y="20.469999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-148.77579" y="20.469999"> 6</tspan> <tspan style="font-size: 12.50px; " x="-142.52428" y="20.469999"> 0</tspan> <tspan style="font-size: 12.50px; " x="-136.27278" y="20.469999"> 2</tspan> <tspan style="font-size: 12.50px; " x="-130.02129" y="20.469999"> 9</tspan> <tspan style="font-size: 12.50px; " x="-120.29395" y="20.469999"> =</tspan> <tspan style="font-size: 12.50px; " x="-108.25356" y="20.469999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-102.00206" y="20.469999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-98.876305" y="20.469999"> 6</tspan> <tspan style="font-size: 12.50px; " x="-92.624809" y="20.469999"> 0</tspan> <tspan style="font-size: 12.50px; " x="-86.373306" y="20.469999"> 9</tspan> <tspan style="font-size: 12.50px; " x="-80.121803" y="20.469999"> 7</tspan> <tspan style="font-size: 12.50px; " x="-73.870308" y="20.469999"> ,</tspan> <tspan style="font-size: 12.50px; " x="-208.03999" y="40.950001"> 1</tspan> <tspan style="font-size: 12.50px; " x="-201.7885" y="40.950001"> 1</tspan> <tspan style="font-size: 12.50px; " x="-195.537" y="40.950001"> 5</tspan> <tspan style="font-size: 12.50px; " x="-189.28551" y="40.950001"> 。</tspan> <tspan style="font-size: 12.50px; " x="-186.15974" y="40.950001"> 4</tspan> <tspan style="font-size: 12.50px; " x="-179.90825" y="40.950001"> 4</tspan> <tspan style="font-size: 12.50px; " x="-170.19342" y="40.950001"> =</tspan> <tspan style="font-size: 12.50px; " x="-158.15303" y="40.950001"> 1</tspan> <tspan style="font-size: 12.50px; " x="-151.90154" y="40.950001"> 1</tspan> <tspan style="font-size: 12.50px; " x="-145.65002" y="40.950001"> 5</tspan> <tspan style="font-size: 12.50px; " x="-139.39853" y="40.950001"> 。</tspan> <tspan style="font-size: 12.50px; " x="-136.27278" y="40.950001"> 4</tspan> <tspan style="font-size: 12.50px; " x="-130.02129" y="40.950001"> 6</tspan> <tspan style="font-size: 12.50px; " x="-120.29395" y="40.950001"> =</tspan> <tspan style="font-size: 12.50px; " x="-108.25356" y="40.950001"> 1</tspan> <tspan style="font-size: 12.50px; " x="-102.00206" y="40.950001"> 1</tspan> <tspan style="font-size: 12.50px; " x="-95.750557" y="40.950001"> 5</tspan> <tspan style="font-size: 12.50px; " x="-89.499054" y="40.950001"> 。</tspan> <tspan style="font-size: 12.50px; " x="-86.373306" y="40.950001"> 4</tspan> <tspan style="font-size: 12.50px; " x="-80.121803" y="40.950001"> 8</tspan> <tspan style="font-size: 12.50px; " x="-73.870308" y="40.950001"> ,</tspan> <tspan style="font-size: 12.50px; " x="-208.03999" y="61.419998"> 5</tspan> <tspan style="font-size: 12.50px; " x="-201.7885" y="61.419998"> 。</tspan> <tspan style="font-size: 12.50px; " x="-198.66275" y="61.419998"> 4</tspan> <tspan style="font-size: 12.50px; " x="-192.41125" y="61.419998"> 9</tspan> <tspan style="font-size: 12.50px; " x="-186.15974" y="61.419998"> 3</tspan> <tspan style="font-size: 12.50px; " x="-179.90825" y="61.419998"> 7</tspan> <tspan style="font-size: 12.50px; " x="-170.19342" y="61.419998"> =</tspan> <tspan style="font-size: 12.50px; " x="-158.15303" y="61.419998"> 5</tspan> <tspan style="font-size: 12.50px; " x="-151.90154" y="61.419998"> 。</tspan> <tspan style="font-size: 12.50px; " x="-148.77579" y="61.419998"> 5</tspan> <tspan style="font-size: 12.50px; " x="-142.52428" y="61.419998"> 0</tspan> <tspan style="font-size: 12.50px; " x="-136.27278" y="61.419998"> 0</tspan> <tspan style="font-size: 12.50px; " x="-130.02129" y="61.419998"> 6</tspan> <tspan style="font-size: 12.50px; " x="-120.29395" y="61.419998"> =</tspan> <tspan style="font-size: 12.50px; " x="-108.25356" y="61.419998"> 5</tspan> <tspan style="font-size: 12.50px; " x="-102.00206" y="61.419998"> 。</tspan> <tspan style="font-size: 12.50px; " x="-98.876305" y="61.419998"> 5</tspan> <tspan style="font-size: 12.50px; " x="-92.624809" y="61.419998"> 0</tspan> <tspan style="font-size: 12.50px; " x="-86.373306" y="61.419998"> 7</tspan> <tspan style="font-size: 12.50px; " x="-80.121803" y="61.419998"> 6</tspan> <tspan style="font-size: 12.50px; " x="-73.870308" y="61.419998"> ,</tspan> <tspan style="font-size: 12.50px; " x="-208.03999" y="81.889999"> 4</tspan> <tspan style="font-size: 12.50px; " x="-201.7885" y="81.889999"> 0</tspan> <tspan style="font-size: 12.50px; " x="-195.537" y="81.889999"> 4</tspan> <tspan style="font-size: 12.50px; " x="-189.28551" y="81.889999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-186.15974" y="81.889999"> 7</tspan> <tspan style="font-size: 12.50px; " x="-179.90825" y="81.889999"> 4</tspan> <tspan style="font-size: 12.50px; " x="-170.19342" y="81.889999"> =</tspan> <tspan style="font-size: 12.50px; " x="-158.15303" y="81.889999"> 4</tspan> <tspan style="font-size: 12.50px; " x="-151.90154" y="81.889999"> 0</tspan> <tspan style="font-size: 12.50px; " x="-145.65002" y="81.889999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-139.39853" y="81.889999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-136.27278" y="81.889999"> 1</tspan> <tspan style="font-size: 12.50px; " x="-130.02129" y="81.889999"> 7</tspan> <tspan style="font-size: 12.50px; " x="-120.29395" y="81.889999"> =</tspan> <tspan style="font-size: 12.50px; " x="-108.25356" y="81.889999"> 4</tspan> <tspan style="font-size: 12.50px; " x="-102.00206" y="81.889999"> 0</tspan> <tspan style="font-size: 12.50px; " x="-95.750557" y="81.889999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-89.499054" y="81.889999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-86.373306" y="81.889999"> 6</tspan> <tspan style="font-size: 12.50px; " x="-80.121803" y="81.889999"> 0</tspan> <tspan style="font-size: 12.50px; " x="-73.870308" y="81.889999"> 。</tspan> <tspan style="font-size: 12.50px; " x="138.57001" y="40.349998"> (</tspan> <tspan style="font-size: 12.50px; " x="142.73351" y="40.349998"> 3</tspan> <tspan style="font-size: 12.50px; " x="148.985" y="40.349998"> 6</tspan> <tspan style="font-size: 12.50px; " x="155.2365" y="40.349998"> )</tspan> </text> </g> </g> </svg></span></p> <div class="floats-partial-section partial-other-wrapper" data-section="tab3"> <div class="floats-partial-content fig-content-tab3"> <table class="table-group" id="tab3"> <tbody> <tr> <td> <table class="table"> <tbody> <tr> <td class="thead-hr" colspan="7"> <hr></td> </tr> <tr class="thead"> <td align="left"></td> <td align="center"><span style="width: 8.6000004px;"> <svg height="10.7375" id="M290" style="vertical-align:-0.13794pt" version="1.1" viewbox="0 0 8.6000004 10.7375" width="8.6000004" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.7375)"> <g transform="translate(72,-63.41)"> <text transform="matrix(1,0,0,-1,-71.95,63.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 15.1375px;"> <svg height="10.8375" id="M291" style="vertical-align:-3.2316pt" version="1.1" viewbox="0 0 15.1375 10.8375" width="15.1375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.8375)"> <g transform="translate(72,-63.33)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 7.7624998px;"> <svg height="9.875" id="M292" style="vertical-align:-2.29482pt" version="1.1" viewbox="0 0 7.7624998 9.875" width="7.7624998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,9.875)"> <g transform="translate(72,-64.1)"> <text transform="matrix(1,0,0,-1,-71.95,66.44)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 19.012501px;"> <svg height="10.9" id="M293" style="vertical-align:-3.27548pt" version="1.1" viewbox="0 0 19.012501 10.9" width="19.012501" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.9)"> <g transform="translate(72,-63.28)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 15.2px;"> <svg height="14.3875" id="M294" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 17.7875px;"> <svg height="14.3875" id="M295" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 17.7875 14.3875" width="17.7875" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td class="thead-hr" colspan="7"> <hr></td> </tr> <tr> <td align="left"> <svg height="11.7875" id="M296" style="vertical-align:-0.13794pt" version="1.1" viewbox="0 0 14.6625 11.7875" width="14.6625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,11.7875)"> <g transform="translate(72,-62.57)"> <text transform="matrix(1,0,0,-1,-71.95,62.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-65.4,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ∗</tspan> </text> </g> </g> </svg>确切的</td><td一个l我gn="center"><span style="width: 54.099998px;"> <svg height="14.5" id="M297" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 54.099998 14.5" width="54.099998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.5)"> <g transform="translate(72,-60.4)"> <text transform="matrix(1,0,0,-1,-71.95,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="9.0271664" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="19.804752" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="26.056252" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-39.64,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> </g> </g> </svg></span></td> <td align="center">5</td><td一个l我gn="center">One hundred.</td><td一个l我gn="center">5</td><td一个l我gn="center">400年</td><td一个l我gn="center">0.6</td></tr> <tr> <td align="left"> <svg height="14.2375" id="M298" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 8.3125 14.2375" width="8.3125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.2375)"> <g transform="translate(72,-60.61)"> <text transform="matrix(1,0,0,-1,-65.8,63.52)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ̂</tspan> <tspan style="font-size: 12.50px; " x="-6.1500001" y="2.72"> </tspan> </text> </g> </g> </svg>估计</td><td一个l我gn="center"><span style="width: 89.262497px;"> <svg height="14.5" id="M299" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 89.262497 14.5" width="89.262497" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.5)"> <g transform="translate(72,-60.4)"> <text transform="matrix(1,0,0,-1,-71.95,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="37.158916" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="47.936501" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="54.188004" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-11.5,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> </g> </g> </svg></span></td> <td align="center">5.6029</td><td一个l我gn="center">115.46</td><td一个l我gn="center">5.5006</td><td一个l我gn="center">405.17</td><td一个l我gn="center">0.67</td></tr> <tr> <td align="left">错误</td><td一个l我gn="center"><span style="width: 46.962502px;"> <svg height="11.5" id="M300" style="vertical-align:-0.27588pt" version="1.1" viewbox="0 0 46.962502 11.5" width="46.962502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,11.5)"> <g transform="translate(72,-62.8)"> <text transform="matrix(1,0,0,-1,-71.95,63.12)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="12.503" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> %</tspan> </text> </g> </g> </svg></span></td> <td align="center">12.06%</td><td一个l我gn="center">15.46%</td><td一个l我gn="center">10.01%</td><td一个l我gn="center">1.29%</td><td一个l我gn="center">11.7%</td></tr> <tr class="table-tr"> <td colspan="7"> <hr class="tbody-hr"></td> </tr> </tbody> </table></td> </tr> </tbody> </table> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">表3</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/tab3/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> 结果当<svg height="14.3875" id="M287" style="vertical-align:-3.25793pt;width:24.674999px;" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg>和<svg height="14.3875" id="M288" style="vertical-align:-3.25793pt;width:24.725px;" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg>是已知的(<svg height="14.875" id="M289" style="vertical-align:-3.25793pt;width:56.712502px;" version="1.1" viewbox="0 0 56.712502 14.875" width="56.712502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.875)"> <g transform="translate(72,-60.1)"> <text transform="matrix(1,0,0,-1,-71.95,63.4)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.27)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.4)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 6</tspan> </text> </g> </g> </svg>)。</d我v></d我v></d我v><d我v class="floats-partial-section partial-carousel-wrapper" data-section="fig11"> <div class="floats-partial-content fig-content-fig11"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.0011" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.0011.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图11</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig11/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.3875" id="M301" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M302" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg> <table> 治愈的例子:比较健康肝细胞的数量,和是已知的。</t一个ble> </div> </div> </div> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig12"> <div class="floats-partial-content fig-content-fig12"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.0012" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.0012.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图12</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig12/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.3875" id="M303" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M304" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg> <table> 治愈的例子:比较受感染的肝细胞的数量,和是已知的。</t一个ble> </div> </div> </div> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig13"> <div class="floats-partial-content fig-content-fig13"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.0013" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.0013.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图13</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig13/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.3875" id="M305" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M306" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg> <table> 治愈的例子:比较病毒载量,,是已知的。</t一个ble> </div> </div> </div> <h5 id="sec6.2">6.2。流行情况</h5> <p>在这里,数据生成使用相同的参数向量<svg height="11.7875" id="M307" style="vertical-align:-0.13794pt;width:14.6625px;" version="1.1" viewbox="0 0 14.6625 11.7875" width="14.6625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,11.7875)"> <g transform="translate(72,-62.57)"> <text transform="matrix(1,0,0,-1,-71.95,62.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.4,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> </g> </g> </svg>在(<一个href="#EEq6.1">31日</一个>),异常的<svg height="14.3875" id="M308" style="vertical-align:-2.29482pt;width:14.1125px;" version="1.1" viewbox="0 0 14.1125 14.3875" width="14.1125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,62.83)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-65.84,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> *</tspan> </text> </g> </g> </svg>,其值是200。也相同的初始条件(<一个href="#EEq6.2">32</一个>)使用。在这种情况下,<svg height="14.75" id="M309" style="vertical-align:-3.25793pt;width:56.712502px;" version="1.1" viewbox="0 0 56.712502 14.75" width="56.712502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 2</tspan> </text> </g> </g> </svg>。正如前面提到的,数据生成使用最初的病毒载量<svg height="14.3875" id="M310" style="vertical-align:-3.25793pt;width:15.2px;" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>有和没有噪声(见表<一个href="//www.newsama.com/journals/cmmm/2011/325470/tab4/" target="_blank">4</一个>)。估计参数,优化过程始于初始值<span class="equation" id="eq24"> <svg height="19.8125" id="M311" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 19.8125" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,19.8125)"> <g transform="translate(72,-56.15)"> <text transform="matrix(1,0,0,-1,94.3,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,100.85,57.63)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,109.2,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.03" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="17.889999" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="24.1415" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="30.393" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="36.644501" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="46.009247" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="55.036411" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="65.8265" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.078003" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,187.53,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,198.4,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="18.404415" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="29.182001" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="35.433502" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,240.09,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 2</tspan> </text> <text transform="matrix(1,0,0,-1,250.96,60.76)"> <tspan style="font-size: 12.50px; " x="65.639999" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="25.006001" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="31.2575" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="37.508999" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="43.760502" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="53.137749" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="59.389252" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="216.91" y="-0.19"> (</tspan> <tspan style="font-size: 12.50px; " x="221.0735" y="-0.19"> 3</tspan> <tspan style="font-size: 12.50px; " x="227.325" y="-0.19"> 7</tspan> <tspan style="font-size: 12.50px; " x="233.57649" y="-0.19"> )</tspan> </text> </g> </g> </svg></span>结果如表所示<一个href="//www.newsama.com/journals/cmmm/2011/325470/tab5/" target="_blank">5</一个>。健康和被感染的肝细胞数量和病毒载量的演进图所示<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig14/" target="_blank">14</一个>,<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig15/" target="_blank">15</一个>,<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig16/" target="_blank">16</一个>,<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig17/" target="_blank">17</一个>。</p> <div class="floats-partial-section partial-other-wrapper" data-section="tab4"> <div class="floats-partial-content fig-content-tab4"> <table class="table-group" id="tab4"> <tbody> <tr> <td> <table class="table"> <tbody> <tr> <td class="thead-hr" colspan="3"> <hr></td> </tr> <tr> <td align="left"></td> <td align="center">病毒载量(<svg height="10.575" id="M313" style="vertical-align:-0.20064pt" version="1.1" viewbox="0 0 12.625 10.575" width="12.625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.575)"> <g transform="translate(72,-63.54)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> </g> </g> </svg>)</td><td一个l我gn="center">病毒载量(<svg height="10.575" id="M314" style="vertical-align:-0.20064pt" version="1.1" viewbox="0 0 12.625 10.575" width="12.625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.575)"> <g transform="translate(72,-63.54)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> </g> </g> </svg>)</td></tr> <tr> <td align="left">时间(<svg height="9.125" id="M315" style="vertical-align:-0.11285pt" version="1.1" viewbox="0 0 5.0124998 9.125" width="5.0124998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,9.125)"> <g transform="translate(72,-64.7)"> <text transform="matrix(1,0,0,-1,-71.95,64.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> </g> </g> </svg>)</td><td一个l我gn="center">(UI /<我>μ</我>L)</td><td一个l我gn="center">(UI /<我>μ</我>L)</td></tr> <tr> <td align="left"></td> <td align="center">(<svg height="14.3875" id="M316" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>没有噪音)</td><td一个l我gn="center">(<svg height="14.3875" id="M317" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>与噪音)</td></tr> <tr> <td align="center" colspan="3"> <hr></td> </tr> <tr> <td align="left">0小时</td><td一个l我gn="center">400年</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M318" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 2</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">2小时</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M319" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M320" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">4个小时</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M321" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M322" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">8小时</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M323" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 4</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M324" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 4</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">16个小时</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M325" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 4</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M326" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">24小时</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M327" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M328" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 4</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">2天</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M329" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M330" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">3天</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M331" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M332" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">4天</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M333" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 2</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M334" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 2</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">6天</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M335" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M336" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">8天</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M337" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M338" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 1</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">10天</td><td一个l我gn="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M339" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 105.2125px;"> <svg height="14.375" id="M340" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 105.2125 14.375" width="105.2125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">14天</td><td一个l我gn="center"><span style="width: 112.7125px;"> <svg height="14.375" id="M341" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.375" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 2</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 112.7125px;"> <svg height="14.375" id="M342" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.375" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 2</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">18天</td><td一个l我gn="center"><span style="width: 112.7125px;"> <svg height="14.375" id="M343" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.375" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 112.7125px;"> <svg height="14.375" id="M344" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.375" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 3</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">22天</td><td一个l我gn="center"><span style="width: 112.7125px;"> <svg height="14.375" id="M345" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.375" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 4</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 112.7125px;"> <svg height="14.375" id="M346" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.375" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.375)"> <g transform="translate(72,-60.5)"> <text transform="matrix(1,0,0,-1,-71.95,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 4</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">26天</td><td一个l我gn="center"><span style="width: 112.7125px;"> <svg height="14.5" id="M347" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.5" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.5)"> <g transform="translate(72,-60.4)"> <text transform="matrix(1,0,0,-1,-71.95,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 112.7125px;"> <svg height="14.5" id="M348" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.5" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.5)"> <g transform="translate(72,-60.4)"> <text transform="matrix(1,0,0,-1,-71.95,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td align="left">30天</td><td一个l我gn="center"><span style="width: 112.7125px;"> <svg height="14.4625" id="M349" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.4625" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.4625)"> <g transform="translate(72,-60.43)"> <text transform="matrix(1,0,0,-1,-71.95,60.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 6</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,65.96)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 6</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 112.7125px;"> <svg height="14.4625" id="M350" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 112.7125 14.4625" width="112.7125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.4625)"> <g transform="translate(72,-60.43)"> <text transform="matrix(1,0,0,-1,-71.95,60.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 8</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="34.383251" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="40.63475" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="46.88625" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="55.913418" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="66.691002" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="72.942505" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,7.25,65.96)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 6</tspan> </text> </g> </g> </svg></span></td> </tr> <tr class="table-tr"> <td colspan="3"> <hr class="tbody-hr"></td> </tr> </tbody> </table></td> </tr> </tbody> </table> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">表4</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/tab4/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> 生成的数据对于流行情况(<svg height="14.75" id="M312" style="vertical-align:-3.25793pt;width:56.712502px;" version="1.1" viewbox="0 0 56.712502 14.75" width="56.712502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 2</tspan> </text> </g> </g> </svg>)。</d我v></d我v></d我v><d我v class="floats-partial-section partial-other-wrapper" data-section="tab5"> <div class="floats-partial-content fig-content-tab5"> <table class="table-group" id="tab5"> <tbody> <tr> <td> <table class="table"> <tbody> <tr> <td class="thead-hr" colspan="6"> <hr></td> </tr> <tr class="thead"> <td align="left"></td> <td align="center"><span style="width: 8.6000004px;"> <svg height="10.7375" id="M355" style="vertical-align:-0.13794pt" version="1.1" viewbox="0 0 8.6000004 10.7375" width="8.6000004" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.7375)"> <g transform="translate(72,-63.41)"> <text transform="matrix(1,0,0,-1,-71.95,63.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 15.1375px;"> <svg height="10.8375" id="M356" style="vertical-align:-3.2316pt" version="1.1" viewbox="0 0 15.1375 10.8375" width="15.1375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.8375)"> <g transform="translate(72,-63.33)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 7.7624998px;"> <svg height="9.875" id="M357" style="vertical-align:-2.29482pt" version="1.1" viewbox="0 0 7.7624998 9.875" width="7.7624998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,9.875)"> <g transform="translate(72,-64.1)"> <text transform="matrix(1,0,0,-1,-71.95,66.44)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 19.012501px;"> <svg height="10.9" id="M358" style="vertical-align:-3.27548pt" version="1.1" viewbox="0 0 19.012501 10.9" width="19.012501" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.9)"> <g transform="translate(72,-63.28)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 17.7875px;"> <svg height="14.3875" id="M359" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 17.7875 14.3875" width="17.7875" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td class="thead-hr" colspan="6"> <hr></td> </tr> <tr> <td align="left"> <svg height="11.7875" id="M360" style="vertical-align:-0.13794pt" version="1.1" viewbox="0 0 14.6625 11.7875" width="14.6625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,11.7875)"> <g transform="translate(72,-62.57)"> <text transform="matrix(1,0,0,-1,-71.95,62.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-65.4,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ∗</tspan> </text> </g> </g> </svg>确切的</td><td一个l我gn="center"><span style="width: 54.099998px;"> <svg height="14.5" id="M361" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 54.099998 14.5" width="54.099998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.5)"> <g transform="translate(72,-60.4)"> <text transform="matrix(1,0,0,-1,-71.95,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="9.0271664" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="19.804752" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="26.056252" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-39.64,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> </g> </g> </svg></span></td> <td align="center">5</td><td一个l我gn="center">200年</td><td一个l我gn="center">5</td><td一个l我gn="center">1.2</td></tr> <tr> <td align="left"> <svg height="14.2375" id="M362" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 8.3125 14.2375" width="8.3125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.2375)"> <g transform="translate(72,-60.61)"> <text transform="matrix(1,0,0,-1,-65.8,63.52)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ̂</tspan> <tspan style="font-size: 12.50px; " x="-6.1500001" y="2.72"> </tspan> </text> </g> </g> </svg>估计</td><td一个l我gn="center"><span style="width: 89.262497px;"> <svg height="14.5" id="M363" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 89.262497 14.5" width="89.262497" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.5)"> <g transform="translate(72,-60.4)"> <text transform="matrix(1,0,0,-1,-71.95,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="37.158916" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="47.936501" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="54.188004" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-11.5,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> </g> </g> </svg></span></td> <td align="center">5.0867</td><td一个l我gn="center">221.38</td><td一个l我gn="center">5.0563</td><td一个l我gn="center">1.117</td></tr> <tr> <td align="left">错误</td><td一个l我gn="center">13.49%</td><td一个l我gn="center">1.73%</td><td一个l我gn="center">10.69%</td><td一个l我gn="center">1.13%</td><td一个l我gn="center">6.92%</td></tr> <tr class="table-tr"> <td colspan="6"> <hr class="tbody-hr"></td> </tr> </tbody> </table></td> </tr> </tbody> </table> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">表5</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/tab5/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> 结果当<svg height="14.3875" id="M351" style="vertical-align:-3.25793pt;width:24.674999px;" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg>,<svg height="14.3875" id="M352" style="vertical-align:-3.25793pt;width:24.725px;" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg>,<svg height="14.3875" id="M353" style="vertical-align:-3.25793pt;width:15.2px;" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>是已知的(<svg height="14.75" id="M354" style="vertical-align:-3.25793pt;width:56.712502px;" version="1.1" viewbox="0 0 56.712502 14.75" width="56.712502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 2</tspan> </text> </g> </g> </svg>)。</d我v></d我v></d我v><d我v class="floats-partial-section partial-carousel-wrapper" data-section="fig14"> <div class="floats-partial-content fig-content-fig14"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.0014" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.0014.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图14</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig14/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.3875" id="M364" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M365" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M366" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg> <table> 流行情况:比较健康的肝细胞的数量,,,已知的。</t一个ble> </div> </div> </div> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig15"> <div class="floats-partial-content fig-content-fig15"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.0015" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.0015.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图15</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig15/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.3875" id="M367" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M368" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M369" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg> <table> 流行情况:比较感染肝细胞数量(肝损害),,是已知的。</t一个ble> </div> </div> </div> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig16"> <div class="floats-partial-content fig-content-fig16"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.0016" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.0016.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图16</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig16/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.3875" id="M370" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M371" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M372" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg> <table> 流行情况:比较病毒载量的演进,,是已知的。</t一个ble> </div> </div> </div> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig17"> <div class="floats-partial-content fig-content-fig17"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.0017" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.0017.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图17</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig17/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.3875" id="M373" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M374" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M375" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg> <table> 流行情况:比较病毒数据和估计病毒载量进化时,,是已知的。</t一个ble> </div> </div> </div> <p>及其95%置信区间估计参数如下:<span class="equation" id="eq25"> <svg height="95.574997" id="M376" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 95.574997" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,95.575)"> <g transform="translate(72,4.46)"> <text transform="matrix(1,0,0,-1,84.33,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="37.158916" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="47.936501" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="54.188004" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,144.78,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,159.12,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="27.656635" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="33.908134" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="40.159637" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="49.186802" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="59.976891" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="66.228394" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,231.6,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,245.94,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.040389" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="18.291889" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.417639" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="27.66914" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="33.920639" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="40.172138" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="49.199306" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="59.976891" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="66.228394" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,318.43,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,329.3,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="-208.03999" y="20.469999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-201.7885" y="20.469999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-198.66275" y="20.469999"> 0</tspan> <tspan style="font-size: 12.50px; " x="-192.41125" y="20.469999"> 8</tspan> <tspan style="font-size: 12.50px; " x="-186.15974" y="20.469999"> 4</tspan> <tspan style="font-size: 12.50px; " x="-179.90825" y="20.469999"> 8</tspan> <tspan style="font-size: 12.50px; " x="-170.19342" y="20.469999"> =</tspan> <tspan style="font-size: 12.50px; " x="-158.15303" y="20.469999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-151.90154" y="20.469999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-148.77579" y="20.469999"> 0</tspan> <tspan style="font-size: 12.50px; " x="-142.52428" y="20.469999"> 8</tspan> <tspan style="font-size: 12.50px; " x="-136.27278" y="20.469999"> 6</tspan> <tspan style="font-size: 12.50px; " x="-130.02129" y="20.469999"> 7</tspan> <tspan style="font-size: 12.50px; " x="-120.29395" y="20.469999"> =</tspan> <tspan style="font-size: 12.50px; " x="-108.25356" y="20.469999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-102.00206" y="20.469999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-98.876305" y="20.469999"> 0</tspan> <tspan style="font-size: 12.50px; " x="-92.624809" y="20.469999"> 8</tspan> <tspan style="font-size: 12.50px; " x="-86.373306" y="20.469999"> 8</tspan> <tspan style="font-size: 12.50px; " x="-80.121803" y="20.469999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-73.870308" y="20.469999"> ,</tspan> <tspan style="font-size: 12.50px; " x="-208.03999" y="40.950001"> 2</tspan> <tspan style="font-size: 12.50px; " x="-201.7885" y="40.950001"> 2</tspan> <tspan style="font-size: 12.50px; " x="-195.537" y="40.950001"> 1</tspan> <tspan style="font-size: 12.50px; " x="-189.28551" y="40.950001"> 。</tspan> <tspan style="font-size: 12.50px; " x="-186.15974" y="40.950001"> 3</tspan> <tspan style="font-size: 12.50px; " x="-179.90825" y="40.950001"> 7</tspan> <tspan style="font-size: 12.50px; " x="-170.19342" y="40.950001"> =</tspan> <tspan style="font-size: 12.50px; " x="-158.15303" y="40.950001"> 2</tspan> <tspan style="font-size: 12.50px; " x="-151.90154" y="40.950001"> 2</tspan> <tspan style="font-size: 12.50px; " x="-145.65002" y="40.950001"> 1</tspan> <tspan style="font-size: 12.50px; " x="-139.39853" y="40.950001"> 。</tspan> <tspan style="font-size: 12.50px; " x="-136.27278" y="40.950001"> 3</tspan> <tspan style="font-size: 12.50px; " x="-130.02129" y="40.950001"> 8</tspan> <tspan style="font-size: 12.50px; " x="-120.29395" y="40.950001"> =</tspan> <tspan style="font-size: 12.50px; " x="-108.25356" y="40.950001"> 2</tspan> <tspan style="font-size: 12.50px; " x="-102.00206" y="40.950001"> 2</tspan> <tspan style="font-size: 12.50px; " x="-95.750557" y="40.950001"> 1</tspan> <tspan style="font-size: 12.50px; " x="-89.499054" y="40.950001"> 。</tspan> <tspan style="font-size: 12.50px; " x="-86.373306" y="40.950001"> 3</tspan> <tspan style="font-size: 12.50px; " x="-80.121803" y="40.950001"> 8</tspan> <tspan style="font-size: 12.50px; " x="-73.870308" y="40.950001"> ,</tspan> <tspan style="font-size: 12.50px; " x="-208.03999" y="61.419998"> 5</tspan> <tspan style="font-size: 12.50px; " x="-201.7885" y="61.419998"> 。</tspan> <tspan style="font-size: 12.50px; " x="-198.66275" y="61.419998"> 0</tspan> <tspan style="font-size: 12.50px; " x="-192.41125" y="61.419998"> 5</tspan> <tspan style="font-size: 12.50px; " x="-186.15974" y="61.419998"> 4</tspan> <tspan style="font-size: 12.50px; " x="-179.90825" y="61.419998"> 4</tspan> <tspan style="font-size: 12.50px; " x="-170.19342" y="61.419998"> =</tspan> <tspan style="font-size: 12.50px; " x="-158.15303" y="61.419998"> 5</tspan> <tspan style="font-size: 12.50px; " x="-151.90154" y="61.419998"> 。</tspan> <tspan style="font-size: 12.50px; " x="-148.77579" y="61.419998"> 0</tspan> <tspan style="font-size: 12.50px; " x="-142.52428" y="61.419998"> 5</tspan> <tspan style="font-size: 12.50px; " x="-136.27278" y="61.419998"> 6</tspan> <tspan style="font-size: 12.50px; " x="-130.02129" y="61.419998"> 3</tspan> <tspan style="font-size: 12.50px; " x="-120.29395" y="61.419998"> =</tspan> <tspan style="font-size: 12.50px; " x="-108.25356" y="61.419998"> 5</tspan> <tspan style="font-size: 12.50px; " x="-102.00206" y="61.419998"> 。</tspan> <tspan style="font-size: 12.50px; " x="-98.876305" y="61.419998"> 0</tspan> <tspan style="font-size: 12.50px; " x="-92.624809" y="61.419998"> 5</tspan> <tspan style="font-size: 12.50px; " x="-86.373306" y="61.419998"> 8</tspan> <tspan style="font-size: 12.50px; " x="-80.121803" y="61.419998"> 1</tspan> <tspan style="font-size: 12.50px; " x="-73.870308" y="61.419998"> 。</tspan> <tspan style="font-size: 12.50px; " x="138.57001" y="30.120001"> (</tspan> <tspan style="font-size: 12.50px; " x="142.73351" y="30.120001"> 3</tspan> <tspan style="font-size: 12.50px; " x="148.985" y="30.120001"> 8</tspan> <tspan style="font-size: 12.50px; " x="155.2365" y="30.120001"> )</tspan> </text> </g> </g> </svg></span></p> <p>现在,只使用病毒载量(<svg height="10.575" id="M377" style="vertical-align:-0.20064pt;width:12.625px;" version="1.1" viewbox="0 0 12.625 10.575" width="12.625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.575)"> <g transform="translate(72,-63.54)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>),第三列在表中<一个href="//www.newsama.com/journals/cmmm/2011/325470/tab4/" target="_blank">4</一个>,我们估计参数<svg height="10.7375" id="M378" style="vertical-align:-0.13794pt;width:8.6000004px;" version="1.1" viewbox="0 0 8.6000004 10.7375" width="8.6000004" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.7375)"> <g transform="translate(72,-63.41)"> <text transform="matrix(1,0,0,-1,-71.95,63.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,<svg height="10.8375" id="M379" style="vertical-align:-3.2316pt;width:15.1375px;" version="1.1" viewbox="0 0 15.1375 10.8375" width="15.1375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.8375)"> <g transform="translate(72,-63.33)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,<svg height="9.875" id="M380" style="vertical-align:-2.29482pt;width:7.7624998px;" version="1.1" viewbox="0 0 7.7624998 9.875" width="7.7624998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,9.875)"> <g transform="translate(72,-64.1)"> <text transform="matrix(1,0,0,-1,-71.95,66.44)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,<svg height="10.9" id="M381" style="vertical-align:-3.27548pt;width:19.012501px;" version="1.1" viewbox="0 0 19.012501 10.9" width="19.012501" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.9)"> <g transform="translate(72,-63.28)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> </text> </g> </g> </svg>,最初的病毒载量<svg height="14.3875" id="M382" style="vertical-align:-3.25793pt;width:15.2px;" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg>。优化过程的初始值<svg height="14.75" id="M383" style="vertical-align:-3.25793pt;width:58.037498px;" version="1.1" viewbox="0 0 58.037498 14.75" width="58.037498" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-56.41,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="24.530886" y="0"> 0</tspan> </text> </g> </g> </svg>和<span class="equation" id="eq26"> <svg height="19.6875" id="M384" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 19.6875" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,19.6875)"> <g transform="translate(72,-56.25)"> <text transform="matrix(1,0,0,-1,98.47,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,105.02,57.74)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,113.37,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.04" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="17.889999" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="24.1415" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="30.393" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="36.644501" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="46.021751" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="52.273251" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,171.9,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 4</tspan> </text> <text transform="matrix(1,0,0,-1,182.76,60.86)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 2</tspan> <tspan style="font-size: 12.50px; " x="18.404415" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="29.182001" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="35.433502" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,224.46,66.03)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 2</tspan> </text> <text transform="matrix(1,0,0,-1,235.33,60.86)"> <tspan style="font-size: 12.50px; " x="71.889999" y="2.51"> 吗?</tspan> <tspan style="font-size: 12.50px; " x="79.82" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="9.364747" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="15.616247" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="21.867746" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="31.244997" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="37.496498" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="43.747997" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="49.999496" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="59.376747" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="65.62825" y="0"> 0</tspan> <tspan style="font-size: 12.50px; " x="232.53999" y="-0.14"> (</tspan> <tspan style="font-size: 12.50px; " x="236.70351" y="-0.14"> 3</tspan> <tspan style="font-size: 12.50px; " x="242.955" y="-0.14"> 9</tspan> <tspan style="font-size: 12.50px; " x="249.2065" y="-0.14"> )</tspan> </text> </g> </g> </svg></span></p> <p>这项研究的结果发表在表<一个href="//www.newsama.com/journals/cmmm/2011/325470/tab6/" target="_blank">6</一个>。估计参数,及其95%置信区间是以下:<span class="equation" id="eq27"> <svg height="121.1625" id="M385" preserveaspectratio="xMaxYMin" style="vertical-align:-0pt;width:700.9375px;" version="1.1" viewbox="0 0 700.9375 121.1625" width="700.9375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,121.1625)"> <g transform="translate(72,24.93)"> <text transform="matrix(1,0,0,-1,84.33,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 4</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 7</tspan> <tspan style="font-size: 12.50px; " x="37.158916" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="47.936501" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="54.188004" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,144.78,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,159.12,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="27.656635" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="33.908134" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="40.159637" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="49.186802" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="59.976891" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="66.228394" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,231.6,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,245.94,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.040389" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="18.291889" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.417639" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="27.66914" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="33.920639" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="40.172138" y="0"> 9</tspan> <tspan style="font-size: 12.50px; " x="49.199306" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="59.976891" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="66.228394" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,318.43,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> - - - - - -</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> <text transform="matrix(1,0,0,-1,329.3,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ,</tspan> <tspan style="font-size: 12.50px; " x="-208.03999" y="20.469999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-201.7885" y="20.469999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-198.66275" y="20.469999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-192.41125" y="20.469999"> 4</tspan> <tspan style="font-size: 12.50px; " x="-186.15974" y="20.469999"> 2</tspan> <tspan style="font-size: 12.50px; " x="-179.90825" y="20.469999"> 3</tspan> <tspan style="font-size: 12.50px; " x="-170.19342" y="20.469999"> =</tspan> <tspan style="font-size: 12.50px; " x="-158.15303" y="20.469999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-151.90154" y="20.469999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-148.77579" y="20.469999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-142.52428" y="20.469999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-136.27278" y="20.469999"> 0</tspan> <tspan style="font-size: 12.50px; " x="-130.02129" y="20.469999"> 8</tspan> <tspan style="font-size: 12.50px; " x="-120.29395" y="20.469999"> =</tspan> <tspan style="font-size: 12.50px; " x="-108.25356" y="20.469999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-102.00206" y="20.469999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-98.876305" y="20.469999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-92.624809" y="20.469999"> 5</tspan> <tspan style="font-size: 12.50px; " x="-86.373306" y="20.469999"> 9</tspan> <tspan style="font-size: 12.50px; " x="-80.121803" y="20.469999"> 3</tspan> <tspan style="font-size: 12.50px; " x="-73.870308" y="20.469999"> ,</tspan> <tspan style="font-size: 12.50px; " x="-208.03999" y="40.950001"> 2</tspan> <tspan style="font-size: 12.50px; " x="-201.7885" y="40.950001"> 1</tspan> <tspan style="font-size: 12.50px; " x="-195.537" y="40.950001"> 4</tspan> <tspan style="font-size: 12.50px; " x="-189.28551" y="40.950001"> 。</tspan> <tspan style="font-size: 12.50px; " x="-186.15974" y="40.950001"> 6</tspan> <tspan style="font-size: 12.50px; " x="-179.90825" y="40.950001"> 0</tspan> <tspan style="font-size: 12.50px; " x="-170.19342" y="40.950001"> =</tspan> <tspan style="font-size: 12.50px; " x="-158.15303" y="40.950001"> 2</tspan> <tspan style="font-size: 12.50px; " x="-151.90154" y="40.950001"> 1</tspan> <tspan style="font-size: 12.50px; " x="-145.65002" y="40.950001"> 4</tspan> <tspan style="font-size: 12.50px; " x="-139.39853" y="40.950001"> 。</tspan> <tspan style="font-size: 12.50px; " x="-136.27278" y="40.950001"> 6</tspan> <tspan style="font-size: 12.50px; " x="-130.02129" y="40.950001"> 2</tspan> <tspan style="font-size: 12.50px; " x="-120.29395" y="40.950001"> =</tspan> <tspan style="font-size: 12.50px; " x="-108.25356" y="40.950001"> 2</tspan> <tspan style="font-size: 12.50px; " x="-102.00206" y="40.950001"> 1</tspan> <tspan style="font-size: 12.50px; " x="-95.750557" y="40.950001"> 4</tspan> <tspan style="font-size: 12.50px; " x="-89.499054" y="40.950001"> 。</tspan> <tspan style="font-size: 12.50px; " x="-86.373306" y="40.950001"> 6</tspan> <tspan style="font-size: 12.50px; " x="-80.121803" y="40.950001"> 5</tspan> <tspan style="font-size: 12.50px; " x="-73.870308" y="40.950001"> ,</tspan> <tspan style="font-size: 12.50px; " x="-208.03999" y="61.419998"> 5</tspan> <tspan style="font-size: 12.50px; " x="-201.7885" y="61.419998"> 。</tspan> <tspan style="font-size: 12.50px; " x="-198.66275" y="61.419998"> 3</tspan> <tspan style="font-size: 12.50px; " x="-192.41125" y="61.419998"> 8</tspan> <tspan style="font-size: 12.50px; " x="-186.15974" y="61.419998"> 2</tspan> <tspan style="font-size: 12.50px; " x="-179.90825" y="61.419998"> 7</tspan> <tspan style="font-size: 12.50px; " x="-170.19342" y="61.419998"> =</tspan> <tspan style="font-size: 12.50px; " x="-158.15303" y="61.419998"> 5</tspan> <tspan style="font-size: 12.50px; " x="-151.90154" y="61.419998"> 。</tspan> <tspan style="font-size: 12.50px; " x="-148.77579" y="61.419998"> 3</tspan> <tspan style="font-size: 12.50px; " x="-142.52428" y="61.419998"> 9</tspan> <tspan style="font-size: 12.50px; " x="-136.27278" y="61.419998"> 1</tspan> <tspan style="font-size: 12.50px; " x="-130.02129" y="61.419998"> 0</tspan> <tspan style="font-size: 12.50px; " x="-120.29395" y="61.419998"> =</tspan> <tspan style="font-size: 12.50px; " x="-108.25356" y="61.419998"> 5</tspan> <tspan style="font-size: 12.50px; " x="-102.00206" y="61.419998"> 。</tspan> <tspan style="font-size: 12.50px; " x="-98.876305" y="61.419998"> 3</tspan> <tspan style="font-size: 12.50px; " x="-92.624809" y="61.419998"> 9</tspan> <tspan style="font-size: 12.50px; " x="-86.373306" y="61.419998"> 9</tspan> <tspan style="font-size: 12.50px; " x="-80.121803" y="61.419998"> 3</tspan> <tspan style="font-size: 12.50px; " x="-73.870308" y="61.419998"> ,</tspan> <tspan style="font-size: 12.50px; " x="-208.03999" y="81.889999"> 4</tspan> <tspan style="font-size: 12.50px; " x="-201.7885" y="81.889999"> 1</tspan> <tspan style="font-size: 12.50px; " x="-195.537" y="81.889999"> 2</tspan> <tspan style="font-size: 12.50px; " x="-189.28551" y="81.889999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-186.15974" y="81.889999"> 9</tspan> <tspan style="font-size: 12.50px; " x="-179.90825" y="81.889999"> 4</tspan> <tspan style="font-size: 12.50px; " x="-170.19342" y="81.889999"> =</tspan> <tspan style="font-size: 12.50px; " x="-158.15303" y="81.889999"> 4</tspan> <tspan style="font-size: 12.50px; " x="-151.90154" y="81.889999"> 1</tspan> <tspan style="font-size: 12.50px; " x="-145.65002" y="81.889999"> 3</tspan> <tspan style="font-size: 12.50px; " x="-139.39853" y="81.889999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-136.27278" y="81.889999"> 6</tspan> <tspan style="font-size: 12.50px; " x="-130.02129" y="81.889999"> 8</tspan> <tspan style="font-size: 12.50px; " x="-120.29395" y="81.889999"> =</tspan> <tspan style="font-size: 12.50px; " x="-108.25356" y="81.889999"> 4</tspan> <tspan style="font-size: 12.50px; " x="-102.00206" y="81.889999"> 1</tspan> <tspan style="font-size: 12.50px; " x="-95.750557" y="81.889999"> 4</tspan> <tspan style="font-size: 12.50px; " x="-89.499054" y="81.889999"> 。</tspan> <tspan style="font-size: 12.50px; " x="-86.373306" y="81.889999"> 4</tspan> <tspan style="font-size: 12.50px; " x="-80.121803" y="81.889999"> 3</tspan> <tspan style="font-size: 12.50px; " x="-73.870308" y="81.889999"> 。</tspan> <tspan style="font-size: 12.50px; " x="138.57001" y="40.349998"> (</tspan> <tspan style="font-size: 12.50px; " x="142.73351" y="40.349998"> 4</tspan> <tspan style="font-size: 12.50px; " x="148.985" y="40.349998"> 0</tspan> <tspan style="font-size: 12.50px; " x="155.2365" y="40.349998"> )</tspan> </text> </g> </g> </svg></span></p> <div class="floats-partial-section partial-other-wrapper" data-section="tab6"> <div class="floats-partial-content fig-content-tab6"> <table class="table-group" id="tab6"> <tbody> <tr> <td> <table class="table"> <tbody> <tr> <td class="thead-hr" colspan="7"> <hr></td> </tr> <tr class="thead"> <td align="left"></td> <td align="center"><span style="width: 8.6000004px;"> <svg height="10.7375" id="M389" style="vertical-align:-0.13794pt" version="1.1" viewbox="0 0 8.6000004 10.7375" width="8.6000004" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.7375)"> <g transform="translate(72,-63.41)"> <text transform="matrix(1,0,0,-1,-71.95,63.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 15.1375px;"> <svg height="10.8375" id="M390" style="vertical-align:-3.2316pt" version="1.1" viewbox="0 0 15.1375 10.8375" width="15.1375" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.8375)"> <g transform="translate(72,-63.33)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 7.7624998px;"> <svg height="9.875" id="M391" style="vertical-align:-2.29482pt" version="1.1" viewbox="0 0 7.7624998 9.875" width="7.7624998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,9.875)"> <g transform="translate(72,-64.1)"> <text transform="matrix(1,0,0,-1,-71.95,66.44)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 19.012501px;"> <svg height="10.9" id="M392" style="vertical-align:-3.27548pt" version="1.1" viewbox="0 0 19.012501 10.9" width="19.012501" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,10.9)"> <g transform="translate(72,-63.28)"> <text transform="matrix(1,0,0,-1,-71.95,66.6)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.34,63.47)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 15.2px;"> <svg height="14.3875" id="M393" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 15.2 14.3875" width="15.2" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-64.76,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg></span></td> <td align="center"><span style="width: 17.7875px;"> <svg height="14.3875" id="M394" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 17.7875 14.3875" width="17.7875" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> </g> </g> </svg></span></td> </tr> <tr> <td class="thead-hr" colspan="7"> <hr></td> </tr> <tr> <td align="left"> <svg height="11.7875" id="M395" style="vertical-align:-0.13794pt" version="1.1" viewbox="0 0 14.6625 11.7875" width="14.6625" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,11.7875)"> <g transform="translate(72,-62.57)"> <text transform="matrix(1,0,0,-1,-71.95,62.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-65.4,67.83)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ∗</tspan> </text> </g> </g> </svg>确切的</td><td一个l我gn="center"><span style="width: 54.099998px;"> <svg height="14.5" id="M396" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 54.099998 14.5" width="54.099998" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.5)"> <g transform="translate(72,-60.4)"> <text transform="matrix(1,0,0,-1,-71.95,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="9.0271664" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="19.804752" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="26.056252" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-39.64,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> </g> </g> </svg></span></td> <td align="center">5</td><td一个l我gn="center">200年</td><td一个l我gn="center">5</td><td一个l我gn="center">400年</td><td一个l我gn="center">1.2</td></tr> <tr> <td align="left"> <svg height="14.2375" id="M397" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 8.3125 14.2375" width="8.3125" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.2375)"> <g transform="translate(72,-60.61)"> <text transform="matrix(1,0,0,-1,-65.8,63.52)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ̂</tspan> <tspan style="font-size: 12.50px; " x="-6.1500001" y="2.72"> </tspan> </text> </g> </g> </svg>估计</td><td一个l我gn="center"><span style="width: 89.262497px;"> <svg height="14.5" id="M398" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 89.262497 14.5" width="89.262497" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.5)"> <g transform="translate(72,-60.4)"> <text transform="matrix(1,0,0,-1,-71.95,60.76)"> <tspan style="font-size: 12.50px; " x="0" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="6.2515001" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="9.3772497" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="15.62875" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="21.880251" y="0"> 5</tspan> <tspan style="font-size: 12.50px; " x="28.13175" y="0"> 3</tspan> <tspan style="font-size: 12.50px; " x="37.158916" y="0"> ×</tspan> <tspan style="font-size: 12.50px; " x="47.936501" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="54.188004" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-11.5,65.93)"> <tspan style="font-size: 8.75px; " x="0" y="0"> −</tspan> <tspan style="font-size: 8.75px; " x="5.99512" y="0"> 5</tspan> </text> </g> </g> </svg></span></td> <td align="center">5.5508</td><td一个l我gn="center">214.62</td><td一个l我gn="center">5.3910</td><td一个l我gn="center">413.68</td><td一个l我gn="center">1.1961</td></tr> <tr> <td align="left">错误</td><td一个l我gn="center">11.2%</td><td一个l我gn="center">11.02%</td><td一个l我gn="center">7.3%</td><td一个l我gn="center">7.8%</td><td一个l我gn="center">3.4%</td><td一个l我gn="center">0.33%</td></tr> <tr class="table-tr"> <td colspan="7"> <hr class="tbody-hr"></td> </tr> </tbody> </table></td> </tr> </tbody> </table> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">表6</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/tab6/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> 结果当<svg height="14.3875" id="M386" style="vertical-align:-3.25793pt;width:24.674999px;" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg>和<svg height="14.3875" id="M387" style="vertical-align:-3.25793pt;width:24.725px;" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> ? ?</tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg>给出了(<svg height="14.75" id="M388" style="vertical-align:-3.25793pt;width:56.712502px;" version="1.1" viewbox="0 0 56.712502 14.75" width="56.712502" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.75)"> <g transform="translate(72,-60.2)"> <text transform="matrix(1,0,0,-1,-71.95,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> ? ?</tspan> </text> <text transform="matrix(1,0,0,-1,-62.7,60.37)"> <tspan style="font-size: 8.75px; " x="0" y="0"> 0</tspan> </text> <text transform="matrix(1,0,0,-1,-54.35,63.5)"> <tspan style="font-size: 12.50px; " x="0" y="0"> =</tspan> <tspan style="font-size: 12.50px; " x="12.027886" y="0"> 1</tspan> <tspan style="font-size: 12.50px; " x="18.279387" y="0"> 。</tspan> <tspan style="font-size: 12.50px; " x="21.405136" y="0"> 2</tspan> </text> </g> </g> </svg>)。</d我v></d我v></d我v><p>估计理论和健康和被感染的肝细胞和病毒载量的演进图所示<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig18/" target="_blank">18</一个>,<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig19/" target="_blank">19</一个>,<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig20/" target="_blank">20.</一个>,<一个href="//www.newsama.com/journals/cmmm/2011/325470/fig21/" target="_blank">21</一个>。</p> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig18"> <div class="floats-partial-content fig-content-fig18"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.0018" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.0018.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图18</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig18/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.3875" id="M399" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M400" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg> <table> 流行情况:比较理论,估计健康时肝细胞的数量和给出了。</t一个ble> </div> </div> </div> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig19"> <div class="floats-partial-content fig-content-fig19"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.0019" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.0019.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图19</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig19/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.3875" id="M401" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M402" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg> <table> 流行情况:比较理论和估计感染肝细胞数量(肝损害)和给出了。</t一个ble> </div> </div> </div> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig20"> <div class="floats-partial-content fig-content-fig20"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.0020" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.0020.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图20</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig20/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.3875" id="M403" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M404" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg> <table> 流行情况:比较理论,估计时病毒载量的演进和给出了。</t一个ble> </div> </div> </div> <div class="floats-partial-section partial-carousel-wrapper" data-section="fig21"> <div class="floats-partial-content fig-content-fig21"> <div class="partial-carousel--single-image"> <img alt="" name="325470.fig.0021" src="https://static-01.hindawi.com/articles/cmmm/volume-2011/325470/figures/325470.fig.0021.jpg"> <br> <strong></strong> </div> </div> <div class="floats-partial-footer"> <div class="floats-partial-caption"> <span class="caption-text">图21</span> <a aria-label="full view" class="caption-partial-url" href="//www.newsama.com/journals/cmmm/2011/325470/fig21/" title="" target="_blank"></a> </div> <div class="floats-partial-caption-text"> <svg height="14.3875" id="M405" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.674999 14.3875" width="24.674999" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.8508799" y="0"> 0</tspan> </text> </g> </g> </svg> <svg height="14.3875" id="M406" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 24.725 14.3875" width="24.725" xmlns="http://www.w3.org/2000/svg"> <g transform="matrix(1.25,0,0,-1.25,0,14.3875)"> <g transform="translate(72,-60.49)"> <text transform="matrix(1,0,0,-1,-71.95,63.79)"> <tspan style="font-size: 12.50px; " x="0" y="0"> </tspan> </text> <text transform="matrix(1,0,0,-1,-61.03,60.66)"> <tspan style="font-size: 8.75px; " x="0" y="0"> </tspan> <tspan style="font-size: 8.75px; " x="3.89464" y="0"> 0</tspan> </text> </g> </g> </svg> <table> 流行情况:比较病毒数据和估计病毒载量进化时和给出了。</t一个ble> </div> </div> </div> <h4 id="discussion">7所示。讨论</h4> <p>首先,我们已经表明丙型肝炎疾病的定性行为进化通过使用三个种群的减少模型(健康和被感染的肝细胞和病毒载量)本质上是相同的,通过使用原始模型提出了(<一个href="#B4">11</一个>(部分<一个href="#sec3">3</一个>和<一个href="#sec4">4</一个>)。尽管流行的一些差异是观察到的情况下,最终他们有相同的行为(部分<一个href="#sec5">5</一个>)。</p> <p>第二个结论,我们估计理论和疾病治愈的情况下通过降低模型的演进,最终将观察到的行为实际上是一样的。尽管在流行的情况下一些进化差异可以指出,阈值参数估计是不够好。</p> <p>第三个是我们的主要结论。这在于表明,减少模型进行数值模拟和帮助,保证肝损害是完全可行的监控没有活检,假设我们有足够数量的病毒载量测量(从统计的角度来看,有两个或三个病毒载量测量每个参数估计,在我们的例子中,从10到15),和合理的好的初始估计的肝组织受损,由一个专家的临床医生和hepatopathologist。说,这是非常重要的监测过程没有任何不便(可靠性、并发症的风险,病人痛苦,和其他消极方面),如发生与常规活检。即使今天经皮活检诊断肝损伤并不那么重要,肝损伤监测是一个有价值的工具除了病毒载量,使可能的一个很好的跟踪。所以,即使我们还没有任何实验研究患者为了模型校准和验证,我们的建议监测病毒载量和肝损伤演化(部分<一个href="#sec6">6</一个>)代表一个创新、价值和可靠的工具来进行丙型肝炎疾病跟踪、基因型和种族因素的考虑<一个href="#B10">3</一个>]。现在这一事实提供了一个理论基础协议用于丙型肝炎治疗没有活检。</p> <h4 id="acknowledgments">确认</h4> <p>作者要感谢马教授。de卢尔德Esteva-Peralta安东尼奥Sarmiento-Galan教授,为他们准备的有价值的建议。特别是,他们要感谢克鲁兹Vargas-De莱昂对他表示引用和评论全球稳定的流行情况。他们也感谢匿名裁判仔细阅读,帮助他们提高。</p> </div> <div class="xml-content"> <h4 class="references" id="references">引用</h4> <ol> <li id="B6">b . a . 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Alavez-Ramirez et al。这是一个开放的分布式下文章<一个rel="license" href="http://creativecommons.org/licenses/by/3.0/">知识共享归属许可</一个>,它允许无限制的使用、分配和复制在任何媒介,提供最初的工作是正确引用。</p> </div> </div> </article> </div> </div> </div> <div class="biblio__Wrapper-sc-1nou1lz-0 eyHfWh journal_article__BiblioIntegratorWidget-sc-12fk6zy-5 dbAANp article_widget biblioWrapper hide"> <hr> <h4 class="biblio__H4-sc-1nou1lz-2 becpDt hrTitleRef">更多相关文章</h4> <div id="biblio_widget" class="biblio__BiblioWrapper-sc-1nou1lz-1 hFGNjP"></div> </div> </div> </div> <div class="threeColumn__RightWrapper-sc-1bf4078-2 jzTMLK rightWrapper" id="rightSectionMenu"> <div> <div class="journal_article__ArticleStickyTopToolbar-sc-12fk6zy-0 gbrQxi article_sticky_top_toolbar"> <div class="sc-cBdUnI hRnXob article_top_toolbar"> <a class="sc-htpNat bUhGXt link sc-jtRfpW dIjoCg sc-exkUMo hymroZ pdf_desktop button__group" href="https://downloads.hindawi.com/journals/cmmm/2011/325470.pdf" aria-label="" target="_blank" id="toolbar__dcNavSmall"><span><img 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height="24"><span class="text">引用</span></span><span class="sc-htoDjs bqeMOy sc-dqBHgY cQgXqt fileArrow icon-colored _3P4iUn1NDM5G77nWCamJ4l icon-themeable" title="" font-size="20"></span></a> </div> </div> <div class="journal_article__ArticleStickyBottomToolbar-sc-12fk6zy-1 isgRZA article_sticky_bottom_toolbar"> <div class="sc-cTjmhe ihmyEq article_bottom_toolbar"> <div class="sc-cugefK itFKcQ accordion" property="background-color" color="#D8D8D8" id="toolbar__dofNav"> <span><img alt="" class="sc-EHOje jOLhQl sc-bfYoXt cGuwDn" title="" role="presentation" src="data:image/svg+xml;base64,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" height="24"><span class="sc-dRFtgE jrsDZP">下载其他格式</span><span class="sc-gkFcWv gWTCXQ">更多的</span></span> <span class="sc-htoDjs bMdQcY sc-gbOuXE jGPvPL icon-colored _1CwL9R82TPl2HxDleeYGDR icon-themeable" title="" font-size="11"></span> </div> <div class="sc-fnwBNb etzuBr"> <a class="sc-htpNat bUhGXt link sc-iNhVCk gWgCNb open_panel" href="//www.newsama.com/downloads/journals/cmmm/2011/325470.xml" aria-label="XML" property="background-color" color="#D8D8D8"> <div class="sc-eAKXzc WHkfb"> XML</d我v><我米g alt="" class="sc-EHOje jOLhQl sc-bfYoXt cGuwDn" title="" role="presentation" 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height="24"><span class="sc-dRFtgE jrsDZP">订单打印副本</span><span class="sc-gkFcWv gWTCXQ">订单</span></span><span class="sc-htoDjs kNoiZu sc-gbOuXE jGPvPL right__icon icon-colored _32KP5uexH-Bgs7Kj8Gk1Tz icon-themeable" title="" font-size="16"></span></a> <div class="sc-hBbWxd kdRRST"> <div class="sc-dyGzUR cHatnS"> <div> 的观点<span>671年</span> </div> <div> 下载<span>584年</span> </div> </div> <div> <div class="sc-drKuOJ kxdGAZ"> <span class="__dimensions_badge_embed__" data-doi="10.1155/2011/325470" data-style="small_circle"></span>引用</d我v></d我v></d我v><nav class="sc-bRBYWo fXBKFa sc-hUfwpO jHPgUP" id="toolbar__iconNav"> <h3 class="sc-Rmtcm hNPrIr">分享文章</h3> <ul class="sc-hzDkRC bnbfTS"> <li class="iconBorder"><a class="sc-htpNat bUhGXt link" href="https://twitter.com/share?url=https://doi.org/10.1155/2011/325470&via=Hindawi" aria-label="Sharing on Twitter" rel="noopener noreferrer" target="_blank"><img alt="" class="sc-EHOje jOLhQl socialTwitter" title="" role="presentation" 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