注意力在Gilles de la妥瑞症

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Gilles de la抽动秽语综合征(TS)是一个基底神经节(BG)障碍,不仅与相关运动过度的运动也有注意力障碍。这个实验试图确定是否公开直接的视觉注意力会影响触觉注意力在TS性能,通过使用vibrotactile选择反应时过程涉及偏差事件发生的概率。参与者被要求(即看。,direct gaze) either at the hand receiving the most (expected) vibrations, or the hand less often stimulated (the unexpected), for both crossed and uncrossed arm postures. Contrary to our predictions, gaze did not influence attentional performance in TS patients. Furthermore, patients were found not to be sensitive to distributions of event probability; that is, they did not demonstrate normal expectancy effects like controls. Attentional deficits in TS (as in Parkinson’s disease, another BG disorder) may pertain more to difficulties in holding rather than in shifting the focus of attention. Moreover, directing attention towards the unexpected locus in the crossed arm posture improved overall performance in both patients and controls, suggesting that increased task demands (e.g., crossed arm posture), and/or unexpected stimulus location, may be alleviated by directed attention. These impairments may stem from dysfunction in the circuits linking the frontal lobes with the BG.

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