TI - Bishoftu Elfora Abattoir屠宰牛肝细胞癌的病理和细胞学研究AB型肝细胞癌(HCC)是最常见的肿瘤之一,已在许多家养动物物种中被描述。因此,这种疾病具有重要的经济意义;因此,本研究旨在描述埃塞俄比亚中部Bishoftu Elfora屠宰场屠宰的牛肝细胞癌的细胞病理学特征。从2017年10月到2018年5月,我们使用宏观、组织病理学和细胞学方法进行了一项横断面研究设计,采用了目的取样技术。为此,共对60头牛进行了肝脏肿瘤检测;然而,只有1/60(0.6%)的病例被发现受肝癌影响。肉眼检查,肝细胞癌在肝脏的不同叶可见软的、白色的多灶性结节(直径10-40毫米)。在切面,肿瘤边界清晰,并被薄的结缔组织分割成小叶。肿瘤中央区呈凹陷并有白色纤维区。 Moreover, on histopathology, the tumors divulged unencapsulated carcinomatous lesions consisting of a thick, compact, somewhat ambiguous trabecular pattern of arrangement that was unglued by thin collagenous stroma. Cytological studies suggest that the tumor cells showed anisocytosis, anisokaryosis, prominent nucleoli, multinuclearity, palisading arrangements of neoplastic cells, increased N : C ratios, light eosinophilic cytoplasm, high mitotic index, and cytoplasmic and intranuclear vacuoles. In conclusion, cytopathological findings support a diagnosis of HCC in the liver; thus, further studies with a large sample size and use of immunohistochemistry are important for further characterization of hepatocellular carcinomas in cattle. SN - 2090-8113 UR - https://doi.org/10.1155/2021/6649172 DO - 10.1155/2021/6649172 JF - Veterinary Medicine International PB - Hindawi KW - ER -