TY -的A2 Jarlier文森特AU -丸,Minwuyelet盟——玛利亚姆,所罗门h . AU - Airgecho Tekle盟——Gadissa Endalamaw AU - Aseffa,亚伯拉罕PY - 2015 DA - 2015/06/09 TI -肺结核患病率,药敏测试,和分枝杆菌分离株的基因来自Dessie肺结核患者的埃塞俄比亚SP - 215015 VL - 2015 AB -由于最初看起来成本很高，在许多结核病负担高的国家，及时诊断和有效治疗结核病通常受到资源缺乏或短缺的阻碍。然而，有效治疗的好处最终会超过经验性治疗的好处。本研究对涂片阳性的新发和再治疗结核病患者的样本进行了横断面研究。收集了社会人口学和艾滋病毒状况的数据。培养样本进行鉴定，常规药物敏感性测试，通过缺失分型和spoligotyping进行分子分型。结果显示，年轻人受到的影响更大。新病例仅按照一般治疗指南进行治疗。16.5%的新发患者出现单药或多药耐药。Spoligotyping共检测到44种基因型，家族H3、T1(4系)和CAS-Delhi(3系)占主导。 Some rare patterns from lineage 7 were also found. Spoligotype pattern, HIV positivity, and previous treatment were not associated with drug resistance. That the vast majority of the patients were new cases and young and the large number of these patients with mono- or multiple drug resistance indicate that most TB cases are due to recent transmissions and that urgent actions are needed to curb the transmissions. SN - 2090-150X UR - https://doi.org/10.1155/2015/215015 DO - 10.1155/2015/215015 JF - Tuberculosis Research and Treatment PB - Hindawi Publishing Corporation KW - ER -