TY - JOUR A2 - Markoski，梅丽莎·梅德罗斯AU - 维埃拉帕拉迪诺，费尔南达AU - 德赖斯·罗德里格斯，朱莉安娜AU - 达席尔瓦，艾琳AU - 戈德堡，安娜卡拉PY - 2019 DA - 2019年6月11日TI - 的免疫调节能力Wharton’s Jelly Mesenchymal Stem/Stromal Cells SP - 3548917 VL - 2019 AB - The benefits attributed to mesenchymal stem/stromal cells (MSC) in cell therapy applications are mainly attributed to the secretion of factors, which exhibit immunomodulatory and anti-inflammatory effects and stimulate angiogenesis. Despite the desirable features such as high proliferation levels, multipotency, and immune response regulation, there are important variables that must be considered. Although presenting similar morphological aspects, MSC collected from different tissues can form heterogeneous cellular populations and, therefore, manifest functional differences. Thus, the source of MSC should be a factor to be considered in the development of novel therapies. The following text presents an updated review of recent research outcomes related to Wharton’s jelly mesenchymal stem/stromal cells (WJ-MSC), harvested from umbilical cords and considered novel and potential candidates for the development of cell-based approaches. This text highlights information on how WJ-MSC affect immune responses in comparison with other sources of MSC. SN - 1687-966X UR - https://doi.org/10.1155/2019/3548917 DO - 10.1155/2019/3548917 JF - Stem Cells International PB - Hindawi KW - ER -