TY - JOUR A2 - 解决了，皮拉尔AU - Petropoulou，安娜D. AU - 罗查，Vanderson PY - 2011 DA - 2011/04/05 TI - 风险因素和选项来提高植活在非血缘脐血移植SP - 610514 VL - 2011AB - 使用脐带无关脐带血（UCB）细胞作为造血干细胞移植的替代来源已广泛主要用于缺少HLA匹配供体的患者。在骨髓UCB本许多优点或动员的外周血从志愿者供体，如快速可用性，不存在供体的风险，和降低的急性移植物抗宿主病的发病率。然而，显著临床问题是延迟直接与造血干细胞在脐带血单元数相关植入。The identification of prognostic factors associated with engraftment that can be easily modified (e.g., strategies for donor choice) and the development of new approaches including use of multiple donors, intrabone injection of UCB, ex vivo expansion, and cotransplantation with accessory cells are of crucial importance in order to circumvent the problem of delayed engraftment after UCB transplantation. Those approaches may increase the quality and availability of UCB for transplantation. SN - 1687-966X UR - https://doi.org/10.4061/2011/610514 DO - 10.4061/2011/610514 JF - Stem Cells International PB - SAGE-Hindawi Access to Research KW - ER -