TY - JOUR A2 - 吉村，孝太郎AU - Hauzeur，让 - 菲利普·AU - 岗集，瓦莱丽PY - 2010 DA - 2010/10/26 TI - 阶段1-3临床试验使用成人干在骨坏死骨不连和骨折SP细胞 - 410170VL - 2010 AB - 骨不连骨折和无菌性骨坏死是具有修复的细胞部分的一些损害两种病理条件：a减少MSC的和成骨细胞活化的。两者都是利用干细胞细胞治疗的很好的候选人。我们做了公布的人体试验的回顾。只有自体骨髓穿刺植入是到现在为止使用。In Nonunion, a direct injection—15 to 150 ml—was made in 4 case series studies. In another, the bone marrow aspirate was concentrated before injection. The results were good. In bone necrosis, only one level 1 study was published. The results at 24 months were positive in terms of reduction of the necrosis and appearance of collapse. In 3 case series studies, a treatment with concentrated bone marrow aspirates was deemed useful with good results in 76 to 96%. These results are interesting but need confirmation by controlled studies. SN - 1687-966X UR - https://doi.org/10.4061/2010/410170 DO - 10.4061/2010/410170 JF - Stem Cells International PB - SAGE-Hindawi Access to Research KW - ER -