TY - JUR A2 - FEIVE，HélioAU - UMEMOTO，乔治奥里吉奥卡，筱牛奥 - Iwasa，Yasuyuki Au - Ozaki，Yoshie Au - Koga，Kayoko Au - Nishimura，Kazumi Au - Tsuboi，Yoshio Py - 2021 - 2021 /04/24 TI - Impact of Progression of Parkinson’s Disease on Swallowing Ability and Oral Environment SP - 5571556 VL - 2021 AB - This study investigated the impact of the severity and treatment of Parkinson’s disease (PD) on the swallowing ability and oral environment of patients. Swallowing dysfunction increases the aspiration risk and may lead to poor oral health among patients with PD. We investigated the influences of PD progression and drug treatment on the swallowing ability and oral environment using simple noninvasive screening measurements. We recruited 87 patients with PD (mean age, 71.9 ± 8.0 years; mean Hoehn and Yahr score, 2.9 ± 0.9). The PD condition was assessed in each patient using the unified Parkinson’s disease rating scale (UPDRS) part III, diet type and oropharyngeal function using the swallowing disturbances questionnaire (SDQ), maximum bite force (MBF), tongue pressure (TP), and oral bacterial count (OBC). Levodopa equivalent daily dose (LEDD) was also calculated for 56 participants. Based on an SDQ score of ≥11, 29.5% of patients were dysphagic, but almost all were still on a regular diet. The SDQ score was positively correlated with disease duration ( rho. = 0.228, P. = 0.047 ）和updrs部分III分数（ rho. = 0.307, P. = 0.007 ）但与OBC负相关（ rho. = −0.289, P. = 0.012 ）。患有SDQ评分<11（Nondysphagic）的患者中obc显着较高（ P. = 0.01 ），患有较高obc的患者需要专业的口腔护理，SDQ评分较低（ P. = 0.03 ）。但是，OBC也与LEDD呈负相关（ rho. = −0.411, P. = 0.004. ）。这些结果表明，参与者之间的吞咽症和吞咽症和PD进展之间的关联的自我意识。此外，口腔环境可能会吞咽功能障碍劣化。患者和临床医生应该意识到更高的LEDD可以增加Xerostomia和相关的口腔健康缺陷。SN - 2090-8083 UR - https：//doi.org/10.1155/2021/5571556 do - 10.1155/2021 / 501155/2021 / 5571556 jf - 帕金森病pb - hindawikw - er -