TY - JOUR TI - Validation of Revised Chinese Version of PD-CRS in Parkinson’s Disease Patients VL - 2020 PY - 2020 DA - 2020/02/19 DO - 10.1155/2020/5289136 UR - https://doi.org/10.1155/2020/5289136 AB - There is a high prevalence of mild cognitive impairment (MCI) and dementia in Parkinson’s disease (PD) patients, but a Chinese version of cognitive rating scale that is specific and sensitive to PD patients is still lacking. The aims of this study are to test the reliability and validity of a Chinese version of Parkinson’s disease-cognitive rating scale (PD-CRS), establish cutoff scores for diagnosis of Parkinson’s disease dementia (PDD) and PD with mild cognitive impairment (PD-MCI), explore cognitive profiles of PD-MCI and PDD, and find cognitive deficits suggesting a transition from PD-MCI to PDD. PD-CRS was revised based on the culture background of Chinese people. Ninety-two PD patients were recruited in three PD centers and were classified into PD with normal cognitive function (PD-NC), PD-MCI, and PDD subgroups according to the cognitive rating scale (CDR). Those PD patients underwent PD-CRS blind assessment by a separate neurologist. The PD-CRS showed a high internal consistency (Cronbach’s Alpha = 0.840). Intraclass Correlation coefficient (ICC) of test-retest reliability reached 0.906 (95% CI 0.860–0.935, ）。的评估者间可靠性ICC为0.899（95％CI 0.848-0.933， ）。PD-CRS had fair concurrent validity with MDRS (ICC = 0.731, 95% CI 0.602–0.816). All the frontal-subcortical items showed significant decrease in PD-MCI compared with the PD-NC group ( ）但仪器皮质项目没有（对抗命名 ，复制一个时钟 ）。与PD-NC组相比PDD所有额叶 - 皮质下和器乐皮质功能表现显著下降（ ）。对于PD-MCI诊断中的截断值是80.5与75.7％的灵敏度和75.0％的特异性，以及用于PDD的诊断是73.5与89.2％的灵敏度和98.9％的特异性。PD-CRS的修订中国版是在PD患者的认知评价一个可靠的，可接受的，有效的，有用的神经心理电池。JF - Parkinson’s Disease SN - 2090-8083 PB - Hindawi SP - 5289136 KW - A2 - Ko, Ji Hyun AU - Tan, Yuyan AU - Liu, Weiguo AU - Du, Juanjuan AU - Hou, Miaomiao AU - Yu, Cuiyu AU - Liu, Yang AU - Cui, Shishuang AU - Yan, Lei AU - Lu, Yizhou AU - Lv, Hong AU - Han, Lijun AU - Wang, Xi AU - Zha, Shengyu AU - Luo, Xiaoguang AU - Tang, Huidong AU - Chen, Shengdi ER -