TY - JOUR A2 - 斯特凡诺，ELKA AU - Cozac，维塔利V. AU - Gschwandtner，乌特AU - 哈茨，弗洛里安AU - Hardmeier，马丁AU - Rüegg，斯蒂芬AU - 富尔，彼得PY - 2016 DA - 2016年4月11日TI - Quantitative EEG and Cognitive Decline in Parkinson’s Disease SP - 9060649 VL - 2016 AB - Cognitive decline is common with the progression of Parkinson’s disease (PD). Different candidate biomarkers are currently studied for the risk of dementia in PD. Several studies have shown that quantitative EEG (QEEG) is a promising predictor of PD-related cognitive decline. In this paper we briefly outline the basics of QEEG analysis and analyze the recent publications addressing the predictive value of QEEG in the context of cognitive decline in PD. The MEDLINE database was searched for relevant publications from January 01, 2005, to March 02, 2015. Twenty-four studies reported QEEG findings in various cognitive states in PD. Spectral and connectivity markers of QEEG could help to discriminate between PD patients with different level of cognitive decline. QEEG variables correlate with tools for cognitive assessment over time and are associated with significant hazard ratios to predict PD-related dementia. QEEG analysis shows high test-retest reliability and avoids learning effects associated with some neuropsychological testing; it is noninvasive and relatively easy to repeat. SN - 2090-8083 UR - https://doi.org/10.1155/2016/9060649 DO - 10.1155/2016/9060649 JF - Parkinson’s Disease PB - Hindawi Publishing Corporation KW - ER -