TY - Jour A2 - Biswas，Sukla Au - Niyibizi，Jean Baptiste Au - Gatera，Emmanuel Kamana Py - 2020 da - 2020/03/27 - 富含组氨酸蛋白2（HRP-2）之间的诊断性能，一种快速疟疾诊断用于诊断疟疾SP的测试和显微镜染色技术 - 5410263 VL - 2020 AB - 疟疾 - 疟疾在卢旺达等大多数热带国家呈现诊断挑战。显微镜仍然是诊断疟疾的金标准，但它是劳动密集型的，取决于考官的技能。疟疾快速诊断测试（RDT）被开发为显微镜的简单，方便的替代品。这种横断面研究是在Rukara保健中心进行的，该中心位于卢旺达东部的东省，卢旺达区。疟疾疟疾案件，在此期间出席Rukara Health Center的疟疾病例^英石2018年6月30日至7月30日，纳入本研究。HRP-2 RDT（Carestart™Malaria Hrp-2（Access Bio，Inc.，Somerset，New Jersety，USA））进行疟疾进行。制备厚厚的涂片，并根据推荐的Giemsa染色;然后在显微镜下观察到载玻片并定量报道;报告的RDT（正面或负面）。RDT和厚涂片结果都记录在数据收集表上。本研究包括共150名研究参与者，87名（58％）女性和63名（42％）的男性。该研究中包括的患者没有接受任何抗疟疾药物。研究参与者的平均年龄是31.6±12.4，大多数参与者在25至44岁之间，少数群体超过65岁。计算RDT（HRP-2）的敏感性，并发现为95.0％，而Giemsa显微镜的敏感性为100％。 The specificity of RDT (HRP-2) was calculated and found to be 59.2%, whereas the specificity of Giemsa microscopy was 100%. Negative and positive predictive values of RDT are 85.4% and 82.7%, respectively. Negative and positive predictive values of Giemsa microscopy were both 100%. According to the results of the current study, the sensitivity, specificity, and both positive and negative predictive values of Giemsa microscopy are higher than those of histidine-rich protein 2-based rapid diagnostic test for malaria. The results obtained in histidine-rich protein 2-based rapid diagnostic test for malaria parasites should be confirmed with tests with high specificity. Further studies should determine the most appropriate type of rapid diagnostic test of malaria diagnosis to be used in combination with Giemsa microscopy. In addition, sensitivity and specificity of RDT (HRP-2) and Giemsa microscopy should be assessed against molecular biology techniques. SN - 1687-9686 UR - https://doi.org/10.1155/2020/5410263 DO - 10.1155/2020/5410263 JF - Journal of Tropical Medicine PB - Hindawi KW - ER -