TY - JOUR A2 - 现地，C. AU - Gboeloh，Lebari Barine AU - OKON，Okpok埃塔AU - 尤度，萨穆埃尔Effiong PY动态 - 2014 DA - 2014年5月11日TI - 抗疟原虫的作用Anthocleista vogelii对小白鼠用人工感染伯氏疟原虫疟原虫（NK 65）SP - 731906 VL - 2014 AB - 目标本研究的是调查的乙醇干树皮提取物的抗疟原虫效果 Anthocleista vogelii不同剂量感染小白鼠 伯氏疟原虫疟原虫（NK 65）。三十六个小鼠分为6组，每组六只小鼠。五组（B₁-B₃，d和G）被感染 伯氏疟原虫疟原虫寄生的红血细胞。基团d，H，和G作为对照。感染后6天，在B组小鼠₁，B₂和B₃were treated orally with 100, 200, and 400 mg/kg body weight of Anthocleista vogelii，分别为六名执行天。Group D was treated with 5 mg/kg body weight of chloroquine while Group G was given distilled water. Group H was not infected and was not treated. It served as the normal control. The extracts exhibited significant （ P < 0.05 ） 的剂量依赖性chemosuppression 伯氏疟原虫。The extract exhibited average chemosuppressive effects of 48.5%, 78.5%, and 86.6% at dose levels of 100, 200, and 400 mg/kg body weight, respectively. Phytochemical screening of the plant extract revealed the presence of saponins, cardiac glycosides, flavonoids, terpenes, alkaloids, and steroid. The acute toxicity (LD₅₀）of the plant was estimated to be 3162 mg/kg body weight. It showed that the stem bark of A. vogelii具有抗疟原虫财产。SN - 2090-0023 UR - https://doi.org/10.1155/2014/731906 DO - 10.1155 /七十三万一千九百○六分之二千○一十四JF - 中华寄生虫研究PB - Hindawi出版公司公司KW - ER -