TY - JOUR A2 - 莱玛克里斯南,孙达拉姆AU - 格里芬,罗伯特J. AU - 威廉姆斯,布伦特W. AU - Koonce,弥敦道A. AU - 比朔夫,约翰C. AU - 宋,张W. AU - 阿苏尔,Rajalakshmi AU -Upreti,米纳克什PY - 2012 DA - 2012/01/04 TI - 血管破坏试剂三氧化二砷增强实体瘤SP的微波热疗 - 934918 VL - 2012 AB - 我们以往的研究证明砷trioxide-(ATO-)诱导肿瘤选择性血管破坏和的抗实体瘤热或放疗效果增强。这些结果表明,辐射,ATO,以及局部热疗的三联做法可能具有抗实体肿瘤的有效治疗功效。Here, we report the antitumor effect of hypofractionated radiation followed by ATO administration and local 42.5 °C hyperthermia and the effects of cisplatin and thermoradiotherapy. We found that the therapeutic efficacy of ATO-based thermoradiotherapy was equal or greater than that of cisplatin-based thermoradiotherapy, and marked evidence of 体内凋亡和肿瘤坏死在ATO处理的肿瘤中观察到。我们的结论是基于ATO-微波热疗是通过使用血管破坏以增强热和放射疗法的效果的有力手段控制肿瘤生长。SN - 1687-8450 UR - https://doi.org/10.1155/2012/934918 DO - 10.1155 /九十三万四千九百一十八分之二千〇一十二JF - 肿瘤学杂志PB的 - Hindawi出版公司公司KW - ER -