TY - JOUR A2 - Tyler, Douglas S. AU - Martin, Robert C. G. AU - Joshi, Jonathan AU - Robbins, Ken AU - Tomalty, Dana AU - O’Hara, Ryan AU - Tatum, Cliff PY - 2009 DA - 2009/10/29 TI - Transarterial Chemoembolization of Metastatic Colorectal Carcinoma with Drug-Eluting Beads, Irinotecan (DEBIRI): Multi-Institutional Registry SP - 539795 VL - 2009 AB - The purpose of this study was to evaluate the patient tolerance and efficacy of delivering locoregional chemotherapy to metastatic colorectal (MC) hepatic metastases via hepatic trans-arterial approach using irinotecan loaded drug eluting beads. This open-label, multi-center, single arm study included 30 MC patients, who had failed first line therapy. Of the 57 total embolization sessions, 12 (21% of sessions) were associated with adverse reactions during or after the treatment. After a median followup of 9 months, response rates by modified RECIST were 75% at 3 months and 66% at 6 months. Hepatic trans-arterial therapy using Irinotecan loaded DC 珠子 TM值 是安全和有效的MCC治疗由一个最小的并发症发生率和可接受的肿瘤反应所证实。SN - 1687-8450 UR - https://doi.org/10.1155/2009/539795 DO - 10.1155 /五十三万九千七百九十五分之二千零九JF - 肿瘤学杂志PB的 - Hindawi出版公司公司KW - ER -