TY - JOUR A2 - Yang, Yan AU - Tian, Yao AU - Yang, Hongyi AU - Liu, Na AU - Li, Yan AU - Chen, Jie PY - 2021 DA - 2021/10/07 TI - Advances in Pathogenesis of Sjögren’s Syndrome SP - 5928232 VL - 2021 AB - Sjögren’s syndrome (SS) is a chronic autoimmune disease of unknown etiology that mainly involves exocrine glands. Patients present with dry mouth and eyes, fever, arthralgia, and other systemic symptoms. In severe cases, the quality of life of patients is affected. At present, there is no cure for SS, and the treatment options are extremely limited. In recent years, studies of patients and animal models have identified abnormalities of immune cell function and cytokines to be involved in SS. A systematic review of the literature may clarify the etiology and pathogenesis of SS, as well as provide a theoretical basis for the development of new drugs for the treatment of SS. SN - 2314-8861 UR - https://doi.org/10.1155/2021/5928232 DO - 10.1155/2021/5928232 JF - Journal of Immunology Research PB - Hindawi KW - ER -