TY - JOUR A2 - Neagu，莫妮卡AU - Janiczek，玛琳娜AU - Szylberg，卢卡斯AU - Antosik，宝琳娜AU - Kasperska，安娜AU - Marszałek，安杰伊PY - 2020 DA - 2020年5月25日TI - IL-的表达水平图17A，IL-17F，IL-17RA和IL-17RC在前列腺癌与考虑到帐户组织学分级根据格里森尺度相比于良性前列腺增生：新的治疗选择SP的在搜索 - 4910595 VL - 2020 AB - 前列腺癌（PCa）是第二个最常见的诊断恶性肿瘤和癌症死亡的男性世界第五大原因。最常见类型的肿瘤是腺癌。前列腺癌是生长缓慢的癌症。发病率随着年龄的增加而增加。的促炎因子如IL-17A，IL-17F，IL-17RA和IL-17RC表情评估使得能够评估炎症过程对前列腺癌的进展的影响。该研究的目的是评估回顾性组织学材料的前列腺分为使用Gleason评分几组。研究是在40名男性与前列腺癌前列腺癌根治术后石蜡块的形式存档组织材料进行。对照组由10名良性前列腺增生（BPH）。 The material was obtained by the transurethral resection of the prostate (TURP). Immunohistochemistry was performed on prepared material using specific primary antibodies against IL-17A, IL-17F, IL-17RA, and IL-17RC. Expression of the antibody to be examined using light microscopy and the Remmele-Stegner score (IRS) in cancer staining was then evaluated. Expression of IL-17 RA was not shown in a group of patients with PCa and in the control group. In the group of patients with Gleason score 8 and 9 PCa, the expression of IL-17A was higher compared to that of IL-17F. In addition, in PCa with an increased grade of Gleason scale, a decrease in the expression of the study inflammatory parameters was found. The inflammatory process has an impact on PCa. A study on IL-17 may become a starting point for further research on an attempt to use, for example, immunotherapy in PCa. SN - 2314-8861 UR - https://doi.org/10.1155/2020/4910595 DO - 10.1155/2020/4910595 JF - Journal of Immunology Research PB - Hindawi KW - ER -