TY - JOUR A2 - Tabarkiewicz, Jacek AU - Amorim, Kelly N. S. AU - Chagas, Daniele C. G. AU - Sulczewski, Fernando B. AU - Boscardin, Silvia B. PY - 2016 DA - 2016/03/24 TI - Dendritic Cells and Their Multiple Roles during Malaria Infection SP - 2926436 VL - 2016 AB - Dendritic cells (DCs) play a central role in the initiation of adaptive immune responses, efficiently presenting antigens to T cells. This ability relies on the presence of numerous surface and intracellular receptors capable of sensing microbial components as well as inflammation and on a very efficient machinery for antigen presentation. In this way, DCs sense the presence of a myriad of pathogens, including 疟原虫SPP。，疟疾的致病剂。尽管许多努力控制这种感染，但疟疾仍然对发病率和死亡率的高率负责。不同的群体表明DCS在 疟原虫感染，数据表明，表型不同的DCS子集是感染期间免疫调节的关键因素。在本次审查中，我们将讨论DCS对抗免疫力抵御不同阶段的重要性 疟原虫，DCS激活的结果，以及目前已知的内容 疟原虫触发此类激活的组件。SN - 2314-8861 UR - https://doi.org/10.1155/2016/2926436 Do - 10.1155/2016 / 2926436 JF - 免疫学研究杂志 - Hindwi Publishing Corporation KW - ER -