TY - Jour A2 - Torti，Carlo Au - Poudrier，Joisiane Au - Chagnon-Choquet，Josiane Au - Roger，Michel Py - 2012 Da - 2012/02/22 Ti - 树突状细胞对HIV感染期间B细胞反应的影响- 592187 VL - 2012年AB - 树突状细胞（DCS）调节B细胞分化，激活和生存，主要通过生产B淋巴细胞刺激剂（Blys / Baff）。据报道，DC种群受到艾滋病毒感染期间的数量，表型和功能，并且这种改变可能有助于B细胞隔室的失调。在此，我们反映了DC对HIV相关的B细胞疾病发病机制的潜在影响，以及DC状态如何调节粘膜B细胞应答的结果，这对于对疾病的控制至关重要。A concept that could be extrapolated to the overall outcome of HIV disease, whereby control versus progression may reside in the host’s capacity to maintain DC homeostasis at mucosal sites, where DC populations present an inherent capacity of modulating the balance between tolerance and protection, and are amongst the earliest cell types to be exposed to the virus. SN - 2314-8861 UR - https://doi.org/10.1155/2012/592187 DO - 10.1155/2012/592187 JF - Clinical and Developmental Immunology PB - Hindawi Publishing Corporation KW - ER -