TY -的A2 Martuzzi Marco AU - Breugelmans奥斯卡AU -阿梅尔,卡罗琳AU -马拉,貂AU -费舍尔,保罗•AU - van de Kassteele Jan AU - Lijzen Johannes盟——Oosterlee阿里盟——Keuken Rinske AU -维瑟,奥托盟——Houthuijs丹尼AU - van Wiechen,Carla PY - 2013 DA - 2013/11 - 13 TI - Lung Cancer Risk and Past Exposure to Emissions from a Large Steel Plant SP - 684035 VL - 2013 AB -我们研究了一家大型钢铁厂周围癌症发病率的空间分布及其与历史暴露的关系。研究人口接近60万。发病率数据收集于1995-2006年。根据历史排放数据,对大气中多环芳烃(PAH)和金属污染浓度进行了模拟。数据分析采用贝叶斯层次泊松回归模型。在毗邻工业区的两个城市,肺癌的标准化发病率(SIR)比平均水平高出40%。发病率增加的部分原因可能是社会经济地位的差异。在最高暴露类别(约4.5万居民)中,经社会经济地位调整后,相对危险度(RR)增加了1.21(1.01-1.43)。升高的rr在男性和女性中是相似的。 Additional analyses in a subsample of the population with personal smoking data from a recent survey suggested that the observed association between lung cancer and plant emission, after adjustment for SES, could still be caused by residual confounding. Therefore, we cannot indisputably conclude that past emissions from the steel plant have contributed to the increased risk of lung cancer. SN - 1687-9805 UR - https://doi.org/10.1155/2013/684035 DO - 10.1155/2013/684035 JF - Journal of Environmental and Public Health PB - Hindawi Publishing Corporation KW - ER -