TY - JOUR A2 - Ahsan, Habibul AU - Luckett, Brian G. AU - Su, L. Joseph AU - Rood, Jennifer C. AU - Fontham, Elizabeth T. H. PY - 2012 DA - 2012/12/24 TI - Cadmium Exposure and Pancreatic Cancer in South Louisiana SP - 180186 VL - 2012 AB - Cadmium has been hypothesized to be a pancreatic carcinogen. We test the hypothesis that cadmium exposure is a risk factor for pancreatic cancer with a population-based case-control study sampled from a population with persistently high rates of pancreatic cancer (south Louisiana). We tested potential dietary and nondietary sources of cadmium for their association with urinary cadmium concentrations which reflect long-term exposure to cadmium due to the accumulation of cadmium in the kidney cortex. Increasing urinary cadmium concentrations were significantly associated with an increasing risk of pancreatic cancer (2nd quartile OR = 3.34, 3rd = 5.58, 4th = 7.70; test for trend P. ≤. 0.0001. ） 。如在科学文献中所记录的那样，镉暴露的潜在来源，发现与胰腺癌的风险增加，包括作为水管工，管道或焊机（或= 5.88）和红肉的高消耗水平（第4四分位数或= 6.18）和谷物（第4四分位数或= 3.38）。目前的吸烟，至少80多年的吸烟，职业接触镉和涂料，在造船厂工作，以及高消耗的谷物，与尿镉浓度增加有统计显着相关。本研究提供了流行病学证据，即镉是潜在的人类胰腺癌。SN - 1687-9805 UR - https://doi.org/10.1155/2012/180186 do - 10.1155 / 2012/180186 jf - 环境与公共卫生杂志 - Hindwi Publishing Corporation Kw - Er -