TY -的A2 -正树,孝盟——周,万盟——你们山东AU - Wang Wei AU - Li Sumei AU -胡,承接PY - 2020 DA - 2020/09/30 TI - COVID-19糖尿病患者的临床特征和次要高血糖SP - 3918723六世- 2020 AB -各种感染的糖尿病患者有更高的风险。因此,这些糖尿病患者可能增加的风险COVID-19,预后较差。到目前为止,对发病机制中的关键作用。本研究旨在调查COVID-19糖尿病患者的临床特点和二级高血糖,以及探索所谓的机制。80年证实COVID-19受试者分为正常组、二次高血糖组和糖尿病组。的严重性COVID-19定义基于诊断和治疗指南SARS-CoV-2出具中国国家健康委员会。根据疾病的严重程度,患者轻度类型和常见的注册为温和的情况下(最小的症状和患者CT阴性结果),而严重的类型和关键类型的病人被登记为严重的病例(阳性患者CT发现和不同程度的临床表现)。糖尿病组的患者比那些正常组,他们中的大多数是男性。糖尿病组,严重病例的比例为57.14%,明显高于其他两组,和32%的COVID-19糖尿病患者诊断为严重的病例。糖尿病组CD4 +细胞计数低于其他两组,而LDH和hs-CRP更高的水平。 Compared with the euglycemia group, the CD3+ cell counts and the CD4+/CD8+ ratio were decreased, whereas the levels of IL-6 were increased in the secondary hyperglycemia group and diabetes group, with the diversities in the diabetes group being especially more significant. The Spearman correlation analysis revealed that the presence of diabetes was positively correlated with age, hs-CRP, LDH, IL-6, CD8+ cells, and severity of COVID-19 and negatively correlated with CD3+ cell counts, CD4+ cell counts, and CD4+/CD8+ ratio. Compared with the other two groups, the diabetes group exhibited more diverse and multifocal features in CT imagings. Diabetes is a risk factor for influence of the progression and prognosis of COVID-19 due to ongoing inflammation and impaired immune response. SN - 2314-6745 UR - https://doi.org/10.1155/2020/3918723 DO - 10.1155/2020/3918723 JF - Journal of Diabetes Research PB - Hindawi KW - ER -