TY - A2的其它约瑟夫盟——Folliero Veronica AU -弗兰,布冯盟——戴尔'Annunziata Federica盟——Giugliano罗莎盟——Foglia Francesco盟——Sperlongano Rossella AU - De菲利皮主持,安娜盟——Finamore莉亚娜盟——Galdiero Massimiliano PY - 2021 DA - 2021/08/14 TI -评价抗生素耐药性的临床应变与医疗设备和生物膜生产中SP - 9033278六世- 2021 AB -微生物生物膜构成严重威胁病人需要医疗设备(MDs)。长时间的植入device-related感染的高风险(DRIs)。DRIs患者经常有负面结果失败后抗生素治疗。耐DRIs主要是由于MDs生物膜的生成受细菌污染。本研究旨在检测生物膜的形成在MD细菌分离和探索他们的抗生素耐药性资料。76 MDs的研究,收集在坎帕尼亚大学医院“Luigi Vanvitelli”2019年10月至2020年9月。隔离和抗生素敏感性试验进行鉴定用基质辅助激光解吸电离时间飞行质谱(MALDI-TOF MS)和凤凰城,正欲。Biofilm-forming能力评估使用细胞培养板(TCP)方法。在94年分离的菌株MDs中,42.7%是革兰氏阳性,40.3%革兰氏阴性,17%念珠菌属的物种。在78个细菌菌株中,43.6%是non-biofilm生产商而56.4%生产的生物膜。 All biofilm producing isolates were sensitive to a limited spectrum of antibiotic classes. All moderate and strong biofilm producers and 81% of weak biofilm producers were Multidrug Resistance (MDR) strains. In contrast, among non-biofilm producers, only 11.8% were classified as MDR strains. Our results highlighted that Sulfamides and Glycopeptides for the major Gram-positive strains and Fluoroquinolones, Carbapenems, and Aminoglycosides for the most represented Gram-negative isolates could be the most suitable therapeutic choice for most biofilm-DRIs. SN - 1687-918X UR - https://doi.org/10.1155/2021/9033278 DO - 10.1155/2021/9033278 JF - International Journal of Microbiology PB - Hindawi KW - ER -