TY - JOUR A2 - Poole, Toni L. AU - Sivanmaliappan, Tamil Selvi AU - Sevanan, Murugan PY - 2011 DA - 2011/11/17 TI - Antimicrobial Susceptibility Patterns ofPseudomonas aeruginosafrom Diabetes Patients with Foot Ulcers SP - 605195 VL - 2011 AB - Pseudomonas aeruginosais an invasive organism that frequently causes severe tissue damage in diabetic foot ulcers. A major problem in P. aeruginosainfection may be that this pathogen exhibits a high degree of resistance to a broad spectrum of antibiotics. The study aimed to isolate and determine the antimicrobial susceptibility patterns of the P. aeruginosapopulation from diabetes patients with foot ulcers attending tertiary care hospitals in and around Coimbatore and their antimicrobial susceptibility pattern. The study was carried out at the Department of Microbiology, Dr. N.G.P. Arts and Science College, Coimbatore, for a period of one year (June 2006 to April 2007). The present study comprised 270 pus specimens collected from diabetic patients with foot ulcers. All pus samples were subjected to gram staining; bacterial culture and subsequently the antibiotic sensitivity to 15 different antibiotics for the confirmed P. aeruginosawere performed as per the standard procedures. Eighteen strains (14.28%) of P. aeruginosafrom 270 diabetic foot ulcers were detected. Almost all the strains exhibited a varying degree of resistance to the antibiotics tested. Multidrug resistance for about 8 to 11 antibiotics was observed among the 55.5% of the isolates. Disk diffusion results show 100% resistance to ampicillin, cefoperazone, erythromycin, norfloxacin, and only cefotaxime, ciprofloxacin exhibited greater activity against Pseudomonas aeruginosa. SN - 1687-918X UR - https://doi.org/10.1155/2011/605195 DO - 10.1155/2011/605195 JF - International Journal of Microbiology PB - Hindawi Publishing Corporation KW - ER -