TY - JOUR A2 - Kotula的-巴勒马乌戈热塔AU - Akalu，约纳斯AU - 莫拉，梅塞雷特Derbew AU - Dessie，Gashaw AU - Ayelign，Birhanu PY - 2020 DA - 2020年5月25日TI - Ghrelin对身体系统的生理效应SP - 1385138 VL - 2020 AB - 生长素释放肽是已发现施加的生理效应过多相对新颖多方面激素。在这次审查中，我们发现/确认，生长素对所有身体系统的影响。这引起食欲;提倡使用碳水化合物作为同时保留脂肪的燃料源;抑制脂质氧化，促进脂肪生成;刺激胃酸分泌和运动性;改善心脏功能;降低血压;并保护肾脏，心脏和大脑。 Ghrelin is important for learning, memory, cognition, reward, sleep, taste sensation, olfaction, and sniffing. It has sympatholytic, analgesic, antimicrobial, antifibrotic, and osteogenic effects. Moreover, ghrelin makes the skeletal muscle more excitable and stimulates its regeneration following injury; delays puberty; promotes fetal lung development; decreases thyroid hormone and testosterone; stimulates release of growth hormone, prolactin, glucagon, adrenocorticotropic hormone, cortisol, vasopressin, and oxytocin; inhibits insulin release; and promotes wound healing. Ghrelin protects the body by different mechanisms including inhibition of unwanted inflammation and induction of autophagy. Having a clear understanding of the ghrelin effect in each system has therapeutic implications. Future studies are necessary to elucidate the molecular mechanisms of ghrelin actions as well as its application as a GHSR agonist to treat most common diseases in each system without any paradoxical outcomes on the other systems. SN - 1687-8337 UR - https://doi.org/10.1155/2020/1385138 DO - 10.1155/2020/1385138 JF - International Journal of Endocrinology PB - Hindawi KW - ER -