TY - JOUR A2 - Winder, Steve AU - Bukoreshtliev, Nickolay Vassilev AU - Hodneland, Erlend AU - Eichler, Tilo Wolf AU - Eifart, Patricia AU - Rustom, Amin AU - Gerdes, Hans-Hermann PY - 2012 DA - 2012/06/06 TI - Partitioning and Exocytosis of Secretory Granules during Division of PC12 Cells SP - 805295 VL - 2012 AB - The biogenesis, maturation, and exocytosis of secretory granules in interphase cells have been well documented, whereas the distribution and exocytosis of these hormone-storing organelles during cell division have received little attention.透度分析与延时显微镜结合后显示,在划分PC12细胞时,隐式粒子显性外围定位保留时间相位期间,但在甲状亚相位期间则明显减少,最后只有少数局部化元相位小粒子相位和调频段期间,隐式粒子展示向细胞中间带的显性运动,并显露出轨迹与spindle微图相联细胞间桥基中隐蔽粒子排出中间体并积聚此外,通过测量单粒度分解,我们显示,在细胞分解的各个阶段,密钥粒子都有能力受控分解最后,我们的数据为细胞分块内密片粒子再分配的复杂分子机制提供新线索,这有助于从F-actin富集皮层流出并沿spindle微图流动SN-1687-8876UR-https://doi.org/101155/2012/805295DO-10.1155/2012/805295JF-国际细胞生物杂志PB-Hindawi出版公司KW-ER-