TY - JOUR A2 - 芬克，欧锦棠 - 金，桑勋AU - 金，吉亨AU - KEUM，宝来AU - 全度妍，韩乔AU - 张，硒炫AU - 崔晟吉盟 - 金，升汉AU- 李，宰民AU - 崔赫很快AU - 金，朴恩善AU - Jeen，尹太AU - 李，洪植AU - 春，胡恩洁AU - 金，张鸭子PY - 2020 DA - 2020/03 /03 TI - A Randomized, Endoscopist-Blinded, Prospective Trial to Compare the Efficacy and Patient Tolerability between Bowel Preparation Protocols Using Sodium Picosulfate Magnesium Citrate and Polyethylene-Glycol (1 L and 2 L) for Colonoscopy SP - 9548171 VL - 2020 AB - Patient compliance during bowel preparation is important for successful colonoscopy. Bowel preparation with polyethylene glycol (PEG), the most commonly used solution for cleansing, involves the unpleasant ingestion of a large amount of liquid. Sodium picosulfate magnesium citrate (SP-MC) solution is an alternative option with better palatability than PEG. Therefore, in this study, we compared the efficacy and patient tolerability among the following three bowel preparation protocols: 2 L PEG-ascorbic acid (ASc), 1 L PEG-ASc plus bisacodyl, and SP-MC 340 mL plus bisacodyl. We conducted a randomized prospective endoscopist-blinded study between August 2018 and January 2019. A total of 311 patients were randomly classified into three groups according to the above-described bowel preparation protocols. To evaluate the efficacy of bowel cleansing, we used the Boston Bowel Preparation Scale. The degree of symptoms and the patients’ satisfaction with each bowel preparation method were investigated using a questionnaire completed before sedation for colonoscopy. The baseline characteristics were similar among the three groups. There was no significant difference in the bowel preparation quality among the three groups. However, the incidence of symptoms, such as abdominal fullness and pain, was significantly lower ( P = 0.006 和0.027，分别），而患者的满意率较高显著（ P = 0.012 ）在SP-MC加比沙可啶组比两个PEG基团。在这项研究中，SP-MC的功效加比沙可啶的解决方案是类似于PEG解决方案。然而，患者的耐受性和满意度均在SP-MC加比沙可啶组比其他组好。总之，使用SP-MC加比沙可啶肠道准备解决的可能是提供良好的肠道清洁和提高患者的依从性更好的方法。SN - 1687-6121 UR - https://doi.org/10.1155/2020/9548171 DO - 10.1155 /九百五十四万八千一百七十一分之二千〇二十JF - 消化内科的研究与实践PB - Hindawi出版KW - ER -