TY - JOUR A2 - Ricci, Chiara AU - Liu, Jiefeng AU - Gong, Yujing AU - He, Miao AU - Zeng, Xinyu AU - Liu, Yiping PY - 2020 DA - 2020/05/21 TI - Clinical Effect of Preservation or Nonpreservation of Left Colic Artery in Total Mesorectal Excision under Laparoscopy: A Meta-analysis SP - 1958573 VL - 2020 AB - Background and Aims。To investigate the clinical effect of preservation or nonpreservation of the left colic artery (LCA) in total mesorectal excision (TME) under laparoscopy. Methods。的单词,如“直肠癌”、“离开公司lonic artery,” and “laparoscopy,” were used as the retrieval terms, and the keyword retrieval method was adopted. The retrieval period was set as from January 1, 2013, to June 1, 2018. We searched databases including PubMed, Web of Science, and China National Knowledge Infrastructure (CNKI) to collect randomized and controlled trials which compared the effect of preservation or nonpreservation of the LCA in TME under laparoscopy. Two researchers independently carried out literature screening, data extraction, and literature quality evaluation; Review Manager 5.3 was used for the meta-analysis. Results。Seven studies including 1467 cases were identified for the meta-analysis. As showed by the meta-analysis, compared with the LCA nonpreservation group, the LCA preservation group had significantly reduced incidence of anastomotic leakage ( OR = 0.44 , CI = 0.30 , 0.65 , P < 0.0001 ) and postoperative urinary and sexual dysfunction ( OR = 0.26 , CI = 0.09 , 0.78 , P = 0.02 ) and significantly shorter time for intestinal function recovery ( WMD = − 0.26 , CI = − 0.41 , − 0.11 , P = 0.0008 ). There were no significant differences between the two groups in the duration of surgery, blood loss, number of dissected lymph nodes, or postoperative hospital stay. Conclusions。From the results, the LCA preservation group seems to achieve comparable success with acceptable safety outcomes. Therefore, this surgical method can be recommended in the clinical practice. SN - 1687-6121 UR - https://doi.org/10.1155/2020/1958573 DO - 10.1155/2020/1958573 JF - Gastroenterology Research and Practice PB - Hindawi KW - ER -