TY - JUR A2 - Gionchetti，Paolo Au - Chou，Jen-Wei Au - Lai，Hsiang-Chun Au - Chang，Chia-Hsi Au - Cheng，Ken-Sheng Au - Feng，Chun-Lung Au - Chen，Tsung-WeiPY - 2019 DA - 2019/06/13 TI - 流行病学和炎症性肠病的临床结果：台湾中部的医院研究SP - 4175923 VL - 2019 AB - 炎症肠病（IBD）的发病率和患病率低但在台湾增加。我们旨在调查台湾中部IBD的流行病学和临床结果。我们回顾性地分析了2000年1月至2018年9月在我们院内诊断的IBD患者。诊断标准基于内窥镜和病理结果。分析了临床特征，治疗方案和治疗结果。共有190例IBD患者（80例，克罗恩病（CD）和110患者，具有溃疡性结肠炎（UC））。诊断的平均年龄为38.4岁（CD：36岁，UC：40岁）。男性患者占大多数患者（71.1％）。雄性对Cd的血对母比为3：1和2.1：1的UC。 Current and ever smokers accounted for 30.5% of all patients. Only 4.2% of patients had a family history of IBD. Extraintestinal manifestations (EIMs) were reported in 7.9%, and colorectal cancers (CRCs) were reported in 2.1% of all patients. In patients with CD, the ileal type was the most common disease phenotype (57.5%), and the stricturing type was the most common disease behavior (60.0%). In patients with UC, left-sided colitis was the predominant disease extent (42.7%). The seroprevalence of hepatitis B virus (HBV) was 13.3%. The incidence of perinuclear anti-neutrophil cytoplasmic antibody (p-ANCA) in patients with UC was 22%. 5-Aminosalicylic acids were the preferred treatment for UC, whereas corticosteroids, immunomodulators, and biologic agents were preferred for CD. In patients with CD, the bowel resection rate was 38.8%, and the incidence of hip avascular necrosis was 3.8%. In Taiwan, patients with IBD showed a male predominance, lack of familial clustering, a higher prevalence of HBV infection, and a lower prevalence of p-ANCA, EIMs, and CRC. Moreover, a higher incidence of the ileal type with poor outcomes of CD and left-sided predominance in UC were found. SN - 1687-6121 UR - https://doi.org/10.1155/2019/4175923 DO - 10.1155/2019/4175923 JF - Gastroenterology Research and Practice PB - Hindawi KW - ER -