TY - JOUR A2 - Sherman, Stuart AU - van der Veek, Patrick P. J. AU - de Vos tot Nederveen Cappel, Wouter H. AU - Langers, Alexandra M. J. AU - van Hoek, Bart PY - 2011 DA - 2011/06/16 TI - Two Patients with Extremely Elevated Tumor Markers: Where Is the Malignancy? SP - 123743 VL - 2011 AB - Serum tumor markers are useful to evaluate a cancer's response to treatment, for early detection of cancer relapse, and, in some cases, to diagnose malignancy. In this paper, we present two patients with significantly elevated serum tumor markers 无恶性疾病的证据。从自身免疫性肝炎的18岁患者的痛苦也显着增加甲胎蛋白（AFP）的水平（2002  μ克/升;normal <10 ug/L). Extensive imaging showed no signs of hepatocellular carcinoma or other cancer, and treatment with Prednisone led to rapid normalization of both liver enzymes and aFP. The second patient, a 60-year-old female with painless jaundice due to biliary stone disease, had very high serum levels of CA19-9 (18,000 kU/L, normal <27 kU/L). Liver biochemistry and serum CA19-9 concentration decreased to almost normal values (45 kU/L) after biliary stenting. These cases demonstrate that serum tumor markers can be elevated in benign disease and are therefore not appropriate to diagnose cancer. SN - 1687-6121 UR - https://doi.org/10.1155/2011/123743 DO - 10.1155/2011/123743 JF - Gastroenterology Research and Practice PB - Hindawi Publishing Corporation KW - ER -