TY -的A2 Litscher格盟——王,已经以非盟- Yu Zhi-Ling AU -潘,思源盟,张易盟——太阳,南盟——朱,培丽盟——贾Zhan-Hong盟——周Shu-Feng AU - Ko, Kam-Ming PY - 2014 DA - 2014/04/30 TI -补充的提取五味子果实果肉,种子,SP - 472638 VL - 2014 AB -五味子(SF)对正常和高胆固醇饮食小鼠脂糖代谢的影响甜(果皮)、酸(果肉)、苦/辣(籽核)和咸(所有部分),可以在体内产生广泛的生物活性。在此,我们研究了丝瓜果肉、种子及其组合(即EtSF-P、EtSF-S或EtSF-P/S)乙醇提取物的影响;研究了正常饮食- (ND-)和高胆固醇饮食- (HCLD-)喂养小鼠的脂质和葡萄糖代谢。在ND和hcld喂养的小鼠中,补充EtSF显著降低了18-47%的肝甘油三酯和胆固醇水平。在hcld喂养的小鼠中,补充EtSF可降低血清甘油三酯水平(约29%),而EtSF-P和EtSF- s /P可提高血清胆固醇水平(分别高达26和44%)。在ND和hcld喂养的小鼠中,EtSF治疗降低了肝糖水平(9-44%)。在hcld喂养的小鼠中,添加EtSF-S或EtSF-S/P(1%和3%)可增加胆道或粪便中TC的含量。然而,在hcld喂养的小鼠中,补充9%的EtSF-S/P可降低胆道TC水平。 EtSF-P or EtSF-S/P supplementation reduced serum alanine aminotransferase activity in HCLD-fed mice. The findings suggested that supplementation with EtSF lowered lipid and glucose accumulation in the liver and increased fecal cholesterol contents in mice. Dietary supplementation with EtSF-P or EtSF-S/P attenuated liver damage in HCLD-fed mice. SN - 1741-427X UR - https://doi.org/10.1155/2014/472638 DO - 10.1155/2014/472638 JF - Evidence-Based Complementary and Alternative Medicine PB - Hindawi Publishing Corporation KW - ER -