TY - JOUR A2 - Tot, Tibor AU - Hero, Emily AU - Carey, Martyn AU - Hero, Isabelle AU - Shaaban, Abeer M. PY - 2018 DA - 2018/09/06 TI -双侧乳头乳区复合体神经纤维瘤:SP - 6702561 VL - 2018 AB -神经纤维瘤病1型是一种常染色体显性遗传疾病，可表现为皮下组织内的多发性神经纤维瘤。乳腺神经纤维瘤很少见，最常发生在乳头-乳晕复合体。33岁女性，双侧大，肉质，乳头乳晕复合体的皮肤赘生物。她接受了双侧诊断性切除病变和宏观，两个乳头标本显示息肉样病变。组织学检查显示双侧神经纤维瘤，包括皮肤及真皮下增生的淡色梭形细胞，细胞核呈波状。免疫组化证实梭形细胞的增殖是神经源性的;S100和神经丝阳性，细胞角蛋白阴性。这与红润的平滑肌增生有关。这个病例显示了一个罕见的乳头乳晕神经纤维瘤发生在皮肤和乳头实质。 Our report considers the differential diagnoses of spindle cell proliferation within the dermis and subcutis of the breast and also other deeper breast spindle cell lesions that may involve the nipple. It aims to provide an approach to diagnosing these lesions examining the literature surrounding breast neurofibromas. SN - 2090-6781 UR - https://doi.org/10.1155/2018/6702561 DO - 10.1155/2018/6702561 JF - Case Reports in Pathology PB - Hindawi KW - ER -