TY - JOUR A2 - Hussain, Showket AU - Alemán-Meza, Lucía AU - Gómez-Macías, Gabriela Sofía AU - Barboza-Quintana, Oralia AU - Garza-Guajardo, Raquel AU - Loya-Solis, Abelardo PY - 2014 DA - 2014/12/22 Ti-骨质巨细胞富含子宫颈的富鳞状细胞癌：案例报告和文献的审查SP -415328 VL -2014 AB-宫颈癌 - 宫颈癌是女性生殖器的最常见的恶性肿瘤全球女性最常见的恶性肿瘤。组织学上85％至90％的宫颈癌是鳞状细胞癌。破骨巨细胞富含鳞状细胞癌是一种异常的组织学变异，其中仅报道了4例。我们介绍了一名49岁妇女，有6个月的阴道出血历史。检查显示子宫颈前唇的2.7 cm多型质量。该患者进行了双侧salpingo-opophorortomy的子宫切除术。从显微镜上看，肿瘤由分化较差的非乳腺素化鳞状细胞癌的浸润巢组成。这些肿瘤细胞之间的散布是许多破骨细胞，具有丰富的嗜酸性细胞质，没有核异型，超染色体或有丝分裂活性。 Immunohistochemistry was performed; CK and P63 were strongly positive in the squamous component and negative in the osteoclastic giant cells, while CD68 and Vimentin were strongly positive in the giant cell population and negative in the squamous component. The patient received chemo- and radiotherapy for recurrent disease identified 3 months later on a follow-up CT scan; 7 months after the surgical procedure the patient is clinically and radiologically disease-free. SN - 2090-6781 UR - https://doi.org/10.1155/2014/415328 DO - 10.1155/2014/415328 JF - Case Reports in Pathology PB - Hindawi Publishing Corporation KW - ER -