TY -的A2 Fujigaki山盟——Nagaharu Keiki盟——杉,Yuka盟,川上Keiki PY - 2021 DA - 2021/05/07 TI -一种罕见的Immunotactoid Glomerulopathy与霍奇金淋巴瘤SP - 5527966六世- 2021 AB - Immunotactoid Glomerulopathy (ITG)的特点是刚果red-negative微管存款,据报道，它是一种罕见的副肿瘤综合征，由血液系统恶性肿瘤、病毒感染或自身免疫性疾病引起。在血液系统恶性肿瘤中，多发性骨髓瘤和其他成熟b细胞恶性肿瘤是最常见的血液系统恶性肿瘤，霍奇金淋巴瘤(HL)是非常罕见的。一位59岁女性因肺部肿块及蛋白尿入院。计算机断层摄影引导下的肺活检证实存在HL期IIA。外周血免疫固定检测免疫球蛋白G (IgG) kappa阳性。肾活检显示系膜增生，内皮下病变有沉积，无浸润。这些沉积物中IgG3、C3和kappa轻链呈阳性，而C1q和lambda轻链呈阴性。电子显微镜显示随机排列的管状结构，直径约为50 nm。我们诊断患者为免疫tactoid肾病和HL。 After systemic chemotherapy, the patient achieved a complete response and loss of proteinuria. On the contrary, her serum monoclonal gammopathy was observed after chemotherapy. The existence of a monoclonal antibody itself might not be a sufficient factor for ITG in some cases, and an additive trigger is necessary for development. SN - 2090-6641 UR - https://doi.org/10.1155/2021/5527966 DO - 10.1155/2021/5527966 JF - Case Reports in Nephrology PB - Hindawi KW - ER -