TY - JOUR A2 - Hirayama, Kouichi AU - Kato, Kazuhiko AU - Kawamura, Tetsuya AU - Terashima, Risa AU - Tsuchiya, Yukiko AU - Takahashi, Yasuhito AU - Kasai, Kenji AU - Yokoo，隆PY - 2020 DA - 2020/05/16 TI -例系统性红斑狼疮/ Antineutrophil细胞质Antibody-Associated血管炎重叠综合征的病理和免疫研究SP - 5698708六世- 2020 AB -系统性红斑狼疮/ Antineutrophil细胞质Antibody-Associated血管炎综合症(系统性红斑狼疮/ AAV重叠OS) describes a pathological condition that presents with overlapping features of two diseases. There have been few reports of SLE/AAV OS and none from Japan. We present the case of a 59-year-old woman admitted with chief complaints of fever and decreased renal function. SLE was suspected due to the identification of four items from the diagnostic criteria of the American College of Rheumatology, including positivity for anti-ds-DNA and antinuclear antibodies. However, pathological findings from the kidney biopsy suggested pauci-immune crescentic glomerulonephritis. She was also diagnosed with AAV according to the Chapel Hill Consensus Conference (CHCC) 2012 definitions and the classification algorithm of AAV. SLE/AAV OS was suspected, we started immunosuppressant therapy, and subsequently her renal function improved. In previous reports, initial immunological and pathological findings generally concur. In cases where clinical and pathological features appear to conflict, as in the present case, a treatment strategy decision should be based on pathological and immunological findings to improve the prognosis of OS. SN - 2090-6641 UR - https://doi.org/10.1155/2020/5698708 DO - 10.1155/2020/5698708 JF - Case Reports in Nephrology PB - Hindawi KW - ER -