TY -的A2 Konstantopoulos科斯塔斯盟——Raffa加布里埃尔A . AU -伯恩斯,戴安娜m . AU -伯恩斯,John j . PY - 2021 DA - 2021/03/27 TI -涂片诊断:刺激细胞性贫血的案例和评审肝硬化SP - 8883335六世- 2021 AB -贫血在肝硬化的病因是多方面的;少了一个公认的引起溶血性贫血是由于刺激细胞,被称为刺激细胞性贫血。我们报告的情况下57岁的女人和酒精性肝硬化出现症状macrocytic贫血和血红蛋白水平的7.4 g / dL和失代偿性的肝脏疾病的迹象。值得注意的是,她没有明显的出血的迹象。进一步检查符合溶血,外围涂片证明刺激细胞。病人使用类固醇和丙种球蛋白治疗,虽然她最终失效。刺激细胞的形态学特征是由于红细胞膜的脂质成分改变,改变其形状,导致脾封存和销毁。这种疾病的特征是一个增加胆固醇的比例对细胞膜磷脂,以及低水平的载脂蛋白和低高密度脂蛋白。刺激细胞的存在是预后不良的指标和高死亡风险的影响。目前,唯一确定的治疗是肝移植。 There is a paucity of literature on the prevalence of this phenomenon and even less about treatment. This case highlights the importance of recognition of spur cell anemia as a cause of anemia in cirrhosis as well as the importance of the peripheral smear in the diagnostic workup. Early recognition can lead to avoidance of unnecessary procedures. Further research is needed to elucidate the true prevalence of spur cell anemia and examine further treatment options. SN - 2090-6560 UR - https://doi.org/10.1155/2021/8883335 DO - 10.1155/2021/8883335 JF - Case Reports in Hematology PB - Hindawi KW - ER -