TY -的A2 Bisse大肠A2 - Kyrtsonis M.-C。A2 - Arellano-Rodrigo大肠A2 - Hamerschlak n . AU - Kapur Sakshi AU -蜡,迈克尔AU -英里,莱文AU -侯赛因,Adnan PY - 2013 DA - 2013/12/03 TI -永久神经性耳聋病人与慢性粒细胞性白血病继发颅内出血SP - 894141六世AB - 2013 - 52岁男性出现在左耳耳鸣和饱腹感的一天。检查显示白细胞计数 685年 × 10 3 / μ L粒细胞系列的显著增加和骨髓前体细胞在外围涂片。最初的印象是慢性粒细胞性白血病白细胞增多,和患者开始水合作用,羟基脲和别嘌呤醇。耐心容忍骨髓活检但从活组织检查网站继续流血过多。结果证实了费城染色体阳性慢性粒细胞性白血病(慢性阶段)。住院的第三天,病人突然发达口齿不清一起摇晃动作涉及的四肢。磁共振成像显示多个出血在整个大脑。羟基脲是一直持续到保险nilotinib批准。在九天的住院治疗,病人突然发达国神经性耳聋。重复磁共振成像显示多个新的出血在整个大脑。颞骨的计算机断层扫描显示左右乳突细胞炎性变化。 Nilotinib was started on day eleven of hospitalization. Patient’s white blood cell count continued to decrease, but there was no improvement in hearing. Four months later, patient was treated with bilateral transmastoid cochlear implants. This case highlights permanent deafness as a hemorrhagic complication secondary to chronic myelogenous leukemia. SN - 2090-6560 UR - https://doi.org/10.1155/2013/894141 DO - 10.1155/2013/894141 JF - Case Reports in Hematology PB - Hindawi Publishing Corporation KW - ER -